Issue 94, 2023
From the journal:

Chemical Communications

Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy†

Qifei Shen,‡a   Kai Gao,‡b   Zhiqin Zhao,a   Anran Gao,a   Yanzi Xu,a   Heng Wang, ORCID logo c   Lingjie Meng,ad   Mingming Zhang ORCID logo b  and  Dongfeng Dang ORCID logo *a  

* Corresponding authors

a School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi’an Jiaotong University, Xi’an, P. R. China
E-mail: dongfengdang@xjtu.edu.cn

b State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi’an Jiaotong University, Xi’an, P. R. China

c College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China

d Instrumental Analysis Center, Xi’an Jiao Tong University, Xi’an, P. R. China

Abstract

Multifunctional metallacycles with solid-state emission are highly important in cancer therapy. Here, an aggregation-induced emission (AIE)-active metallacycle of DTPABT-MC-R is developed with efficient emission in the NIR region in the solid state (PLQYs = 4.92%). DTPABT-MC-R-based nanoparticles also display excellent photo-stability, and impressive photosensitive characteristics (ROS efficiency = 10.74%), finally leading to applications in cellular imaging and photodynamic therapy (PDT).

Graphical abstract: Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D3CC04166B
Article type
Communication
Submitted
25 ago 2023
Accepted
01 nov 2023
First published
02 nov 2023

Chem. Commun., 2023,59, 14021-14024

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Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

Q. Shen, K. Gao, Z. Zhao, A. Gao, Y. Xu, H. Wang, L. Meng, M. Zhang and D. Dang, Chem. Commun., 2023, 59, 14021 DOI: 10.1039/D3CC04166B

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