This review highlights advances in one-pot multicomponent synthesis of naphthyridine derivatives, focusing on efficient, atom-economical methods, diverse scaffolds and mechanistic insights fostering innovation in organic synthesis.
Original fluorescent dyes containing 1,6-naphthyridin-7(6H)-one have been synthesized and their optical properties have been studied.
An exceptional discovery of intermolecular cascade annulation for dihydrobenzo[b][1,8]naphthyridines involving specific aniline fragment transfer between Michael addition and SNAr has been reported.
A versatile cascade annulation protocol to access 1,6-naphthyridine and isochromeno[4,3-c]quinoline derivatives from 2-alkynylcyclopropanes is reported.
Anionic hydroxy N-heterocycles exhibit exceptional CO2 capture through cooperative binding, further stabilized by cation interactions—unveiling a promising route to next-generation adsorbents, as demonstrated by DFT and MESP analyses.