Enabling tools for continuous-flow biphasic liquid–liquid reaction

Abstract

Flow chemistry has attracted considerable attention as it offers several advantages over conventional batch chemistry. Several multiphase reactions, including liquid–liquid reactions, are more efficient in flow due to intensified mass transfer. This observation has led to many developments of enabling tools in recent years. In this minireview, an up-to-date overview of such tools will be highlighted. In addition, interesting examples of the integrated continuous-flow process with liquid–liquid reactions will also be presented.