Issue 14, 2024

An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

Abstract

Ginger (Zingiber officinale Roscoe) has traditionally been used as a cooking spice and herbal medicine for treating nausea and vomiting. More recently, ginger was found to effectively reduce the risk of diseases such as gastroenteritis, migraine, gonarthritis, etc., due to its various bioactive compounds. 6-Shogaol, the pungent phenolic substance in ginger, is the most pharmacologically active among such compounds. The aim of the present study was to review the pharmacological characteristic of 6-shogaol, including the properties of anti-inflammatory, antioxidant and antitumour, and its corresponding molecular mechanism. With its multiple mechanisms, 6-shogaol is considered a beneficial natural compound, and therefore, this review will shed some light on the therapeutic role of 6-shogaol and provide a theoretical basis for the development and clinical application of 6-shogaol.

Graphical abstract: An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

Article information

Article type
Review Article
Submitted
31 out 2023
Accepted
07 jan 2024
First published
08 jan 2024

Food Funct., 2024,15, 7252-7270

An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

C. Yang, W. Chen, B. Ye and K. Nie, Food Funct., 2024, 15, 7252 DOI: 10.1039/D3FO04753A

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