Issue 4, 2018

Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

Abstract

The selective manipulation and incubation of individual picoliter drops in high-throughput droplet based microfluidic devices still remains challenging. We used a surface acoustic wave (SAW) to induce a bubble in a 3D designed multi-trap polydimethylsiloxane (PDMS) device to manipulate multiple droplets and demonstrate the selection, incubation and on-demand release of aqueous droplets from a continuous oil flow. By controlling the position of the acoustic actuation, individual droplets are addressed and selectively released from a droplet stream of 460 drops per s. A complete trapping and releasing cycle can be as short as 70 ms and has no upper limit for incubation time. We characterize the fluidic function of the hybrid device in terms of electric power, pulse duration and acoustic path.

Graphical abstract: Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

Article information

Article type
Paper
Submitted
01 jul 2017
Accepted
16 nov 2017
First published
17 nov 2017
This article is Open Access
Creative Commons BY-NC license

Analyst, 2018,143, 843-849

Fast selective trapping and release of picoliter droplets in a 3D microfluidic PDMS multi-trap system with bubbles

R. W. Rambach, P. Biswas, A. Yadav, P. Garstecki and T. Franke, Analyst, 2018, 143, 843 DOI: 10.1039/C7AN01100H

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