Issue 20, 2016

A triblock terpolymer vs. blends of diblock copolymers for nanocapsules addressed by three independent stimuli

Abstract

Stimuli-responsive micro- to nano-scale containers have gained increasing attention due to their unique potential to selectively release payloads under specific environmental conditions. We report here novel triple stimuli-responsive nanocapsules that selectively respond to changes in temperature, pH value, and redox potential. The nanocapsules were prepared from either a triple responsive triblock terpolymer or a blend of responsive diblock copolymers, both synthesized by sequential anionic polymerization. We then compared the release performance of nanocapsules under oxidative conditions and changes of temperature or pH value. Our results reveal the close correlation between the release properties of stimuli-responsive nanocontainers and the microstructure of the polymer shell. In fact, the microphase separation between the responsive diblock copolymers across the shell significantly hinders the triggered release of the payload from the nanocapsules. These results demonstrate that the fine morphology of triblock terpolymers can be exploited to achieve the triggered release of payloads from polymer nanocontainers upon application of three different external triggers.

Graphical abstract: A triblock terpolymer vs. blends of diblock copolymers for nanocapsules addressed by three independent stimuli

Supplementary files

Article information

Article type
Paper
Submitted
24 fev 2016
Accepted
14 abr 2016
First published
14 abr 2016
This article is Open Access
Creative Commons BY license

Polym. Chem., 2016,7, 3434-3443

A triblock terpolymer vs. blends of diblock copolymers for nanocapsules addressed by three independent stimuli

S. Behzadi, M. Gallei, J. Elbert, M. Appold, G. Glasser, K. Landfester and D. Crespy, Polym. Chem., 2016, 7, 3434 DOI: 10.1039/C6PY00344C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements