Issue 10, 2021

Emerging point-of-care technologies for anemia detection

Abstract

Anemia, characterized by low blood hemoglobin level, affects about 25% of the world's population with the heaviest burden borne by women and children. Anemia leads to impaired cognitive development in children, as well as high morbidity and early mortality among sufferers. Anemia can be caused by nutritional deficiencies, oncologic treatments and diseases, and infections such as malaria, as well as inherited hemoglobin or red cell disorders. Effective treatments are available for anemia upon early detection and the treatment method is highly dependent on the cause of anemia. There is a need for point-of-care (POC) screening, early diagnosis, and monitoring of anemia, which is currently not widely accessible due to technical challenges and cost, especially in low- and middle-income countries where anemia is most prevalent. This review first introduces the evolution of anemia detection methods followed by their implementation in current commercially available POC anemia diagnostic devices. Then, emerging POC anemia detection technologies leveraging new methods are reviewed. Finally, we highlight the future trends of integrating anemia detection with the diagnosis of relevant underlying disorders to accurately identify specific root causes and to facilitate personalized treatment and care.

Graphical abstract: Emerging point-of-care technologies for anemia detection

Article information

Article type
Critical Review
Submitted
07 dez 2020
Accepted
13 mar 2021
First published
31 mar 2021

Lab Chip, 2021,21, 1843-1865

Emerging point-of-care technologies for anemia detection

R. An, Y. Huang, Y. Man, R. W. Valentine, E. Kucukal, U. Goreke, Z. Sekyonda, C. Piccone, A. Owusu-Ansah, S. Ahuja, J. A. Little and U. A. Gurkan, Lab Chip, 2021, 21, 1843 DOI: 10.1039/D0LC01235A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements