This review article demonstrates recent advanced cascade annulation strategies for preparing highly functionalized carbazoles and their related polyaromatic heterocyclic compounds enabled by Lewis acid catalysts.
The carbazole ring construction has been achieved via annulation, C–H activation, carboamination, hydroarylation and cycloaddition reactions. The synthesized scaffolds exhibit various biological activities and participate in drug development.
This review summarizes recent developments in the field of oxidative preparation of bromoarenes and bromoheteroarenes covering from 2012 to 2022.
A gold(I)-catalyzed protecting-group-free benzannulation approach to functionalized NH-carbazoles was accomplished via the hydroarylation of alkynes with 2-alkenylindoles.
Controlled regioselective mono- and di-arylation of carbazoles using dual palladium–photoredox catalysis.