This review summaries the advances in Au-catalyzed asymmetric alkyne transformations over the past two decades. It is organized by the key intermediates and the chirality induction models, offering a toolkit for the implement of asymmetric catalysis.
This review provides an overview of gold-catalyzed reactions for quinoline synthesis which have been described so far.
This review summarizes the latest trends and developments of isoxazole-enabled alkyne amination reactions and their applications in divergent heterocycle synthesis.
This review highlights a curated selection of publications utilizing homogeneous gold-catalyzed cycloaddition and cyclization reactions for the total synthesis of natural products reported from 2016 to mid-2023.
DFT calculations reveal that a non-classical Au⋯H–C hydrogen bond, not ring strain, is the key determinant of chemoselectivity in the gold-catalyzed C–H insertion to form cyclobutanones versus cyclopentanones.