Deploying nucleic acids-loaded plant-derived exosomes as green nano gadget in cancer gene therapy

Marola Paula Fawzy, Hatem A. F. M. Hassan, Muhammad Umair Amin, Eduard Preis, Udo Bakowsky and Sherif Ashraf Fahmy

Mater. Adv., 2025, 6, 1230
DOI: 10.1039/D4MA01189A

Antibody-functionalized lipid nanocarriers for RNA-based cancer gene therapy: advances and challenges in targeted delivery

Nadine Wafik Nabih, Hatem A. F. M. Hassan, Eduard Preis, Jens Schaefer, Asaad Babker, Anass M. Abbas, Muhammad Umair Amin, Udo Bakowsky and Sherif Ashraf Fahmy

Nanoscale Adv., 2025, 7, 5905
DOI: 10.1039/D5NA00323G

Unveiling the role of RAI14 in cancer: Biological significance and translational perspectives

Zhi-Xiong Chong

Seminars in Oncology, 2025, 52, 152412
DOI: 10.1016/j.seminoncol.2025.152412

Emerging role of transfer RNA-derived small RNAs (tsRNAs) in hepatocellular carcinoma

Abdelhamid M. Abdelhamid, Tasneem Abaza, Waleed T. Kotb, Adham H. Mohamed, Mohamed Z. Gad, Ayman M. Metwally, Cédric Coulouarn and Rana A. Youness

Expert Review of Molecular Diagnostics, 2025, 25, 939
DOI: 10.1080/14737159.2025.2600544

Harnessing miRNA dynamics in HIV-1-infected macrophages: Unveiling new targeted therapeutics using systems biology

R. Harshithkumar, Mollina Kaul, Madhuri Chandane-Tak, Nikhat J. Siddiqi, Abdul Malik, Abdul Arif Khan and Anupam Mukherjee

Comput Struct Biotechnol J, 2025, 27, 1754
DOI: 10.1016/j.csbj.2025.04.040

Nanotherapeutics to Overcome Chemotherapy Resistance in Ovarian Cancer

Shaheen Mahira, Priyadarshini Sathe, Siddharth Krishnan, Rahaman Shaik and Vivek Pamula

Pharm Res, 2026
DOI: 10.1007/s11095-026-04020-8

Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects

Feng Xu, Ke Wang, Kaizhong Lu, Tianlun Hou, Yuan Chen, Xian Wang and Hongchuan Jin

Advanced Science, 2026
DOI: 10.1002/advs.75837

Preparation and Characterization of Tiamulin-Loaded Niosomes for Oral Bioavailability Enhancement in Mycoplasma-Infected Broilers

Shimaa G. Abonashey, Amr Gamal Fouad, Hatem A. F. M. Hassan, Ahmed H. El-Banna, Mostafa A. Shalaby, Elham Mobarez, Sherif Ashraf Fahmy and Hossny A. El-Banna

Micro, 2024, 4, 734
DOI: 10.3390/micro4040045

Harnessing the power of ternary nanocomposites in comprehensive cancer management

Anam Nizam, Nawal Shireen, Mohd. Rahil Hasan, Jagriti Narang, Furqan Choudhary, Amber Rizwan, Ubaid Mushtaq Naikoo, Usaid Ahmad, Atul Kumar and Humaira Farooqi

Discov. Sens., 2025, 1
DOI: 10.1007/s44397-025-00025-x

Navigating the tumor landscape: VEGF, MicroRNAs, and the future of cancer treatment

K.P. Ameya, P.P. Ashikha Shirin Usman and Durairaj Sekar

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2025, 1868, 195091
DOI: 10.1016/j.bbagrm.2025.195091

Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition

Jedidja Puttemans, Yasmine Brammerloo, Karim Blibek, Jeremy Blavier, Thandokuhle Ntombela, Inge Van Molle, Julie Joseph, Julien Olivet, Deeya Saha, Manon Degey, Malik Hamaidia, Pooja Jain, Piel Geraldine, Pascale Zimmermann, Dae‐Kyum Kim, Dominique Baiwir, Makon‐Sébastien Njock, Franck Dequiedt, Kourosh Salehi‐Ashtiani, Steven Ballet, Alexander N. Volkov, Jean‐Claude Twizere and Sibusiso B. Maseko

J of Extracellular Vesicle, 2025, 14
DOI: 10.1002/jev2.70137

miR-146a-5p suppresses migration and downregulates vimentin and MMP-9 expression in gastric cancer cells

Amir Baghbanzadeh, Shima Rahmani, Sahand Eslami, Mahya Ahmadpour Youshanlui, Nadia Shafiee, Atefe Shafiee, Amirreza Khalaji and Behzad Baradaran

Discov Onc, 2025, 16
DOI: 10.1007/s12672-025-02929-x

Galectins: a promising arsenal of novel immunotherapeutic weapons in oncology tunned by an array of non-coding RNAs

Alyaa Dawoud, Tasneem Abaza, Yomna Youssef, Dana Ahmed Seada, Adham H. Mohamed, Mai F. Ragab, Jana Mohamed Fahmy, Hana El Hassan El Masry, Mary George Sabry, Marola Paula Fawzy, Kerolos Ashraf Daniel, Mona Rady, Nabila Hamdi and Rana A. Youness

Critical Reviews in Biochemistry and Molecular Biology, 2025, 60, 256
DOI: 10.1080/10409238.2025.2567334

Emerging nanoimmunotherapeutic strategies for breast cancer

Gauri Panzade, Atharva Anand Mahajan, Siva Parsad Panda, Ujjayita Chowdhury, Rohit Krishnan Iyer, Subhrojyoti Ghosh, Madhurima Koley, Akanksha Bhattacharya, Avishek Chatterjee, Anuvab Dey, Chandrika Sarkar, Ankita Chowdhury, Bhaskarjyaa Chatterjee, Souvadra Das, Shrimanti Das, Souhardya Bandyopadhyay, Ramya Lakshmi Rajendran, Prakash Gangadaran, Byeong-Cheol Ahn and Saurabh Kumar Jha

Discov Onc, 2026, 17
DOI: 10.1007/s12672-026-04894-5

Modulating PhpC bioavailability and cellular activity in lung cancer cells via gold nanoparticle functionalization

Daniela Alexandre, Alexandra R. Fernandes, Robert H.E. Hudson, David Monchaud, Pedro V. Baptista and Carla Cruz

Journal of Drug Delivery Science and Technology, 2026, 122, 108457
DOI: 10.1016/j.jddst.2026.108457

Emerging strategies to overcome chemotherapy resistance in breast cancer

Heidi A. Abouzeid, Xuemei Liu and Ahmed Abuelhana

Discov Med, 2025, 2
DOI: 10.1007/s44337-025-00470-y

MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells

Rowan Abdelbary, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby and Ahmed Ihab Abdelaziz

Front. Oncol., 2025, 14
DOI: 10.3389/fonc.2024.1523068

Non-coding RNAs in gene therapy: mechanisms, delivery strategies, and clinical translation

Ali Abuhaliema, Lobna Gharaibeh, Eman Jaradat, Mohaned Hammad and Walhan Alshaer

PHAR, 2026, 73, 1
DOI: 10.3897/pharmacia.73.e173259

Advancing cancer therapeutics: MicroRNA delivery via nano-niosomes

Avneet Kaur, Sunaina Bhuker, Adesh k. Saini and Reena V. Saini

Journal of Drug Delivery Science and Technology, 2026, 120, 108198
DOI: 10.1016/j.jddst.2026.108198

Advances in nucleic acid delivery using nanocarriers for gene therapy in cancer: A narrative review

Mohsen Davari, Navvabeh Salarizadeh, Kiavash Hushmandi, Hadi Esmaeili Gouvarchin ghaleh, Ahmad Asoodeh and Vahid Nazarpour

Critical Reviews in Oncology/Hematology, 2026, 223, 105367
DOI: 10.1016/j.critrevonc.2026.105367

MicroRNAs Modulating Cancer Immunotherapy Mechanisms and Therapeutic Synergies

Naorem Loya Mangang, Samantha K. Gargasz, Sai Ghanesh Murugan, Munish Kumar, Girish C. Shukla and Sivakumar Vijayaraghavalu

Cancers, 2025, 17, 3978
DOI: 10.3390/cancers17243978

Molecular insight into the therapeutic potential of miR-34a in retinoblastoma

Pouya Goleij, Mohammad Amin Khazeei Tabari, Aryan Rezaee, Pantea Majma Sanaye, Ali Kheirandish, Khalaf F. Alsharif, Maria Daglia, Danaé S. Larsen, Haroon Khan and Mohadeseh Poudineh

Naunyn-Schmiedeberg's Arch Pharmacol, 2025, 398, 16913
DOI: 10.1007/s00210-025-04463-7

Current advances in the therapeutic potential of scutellarin: Novel applications, mechanisms, and future challenges

Great Iruoghene Edo, Alice Njolke Mafe, Patrick Othuke Akpoghelie, Tubi Abiola O․, Ebuka Chukwuma Umelo, Emad Yousif, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Rapheal Ajiri Opiti, Chioma Judith Madueke, Arthur Efeoghene Athan Essaghah, Huzaifa Umar and Ahmed A. Alamiery

Phytomedicine Plus, 2025, 5, 100754
DOI: 10.1016/j.phyplu.2025.100754