Protection-free fabrication of glycopolymer-decorated electrodes for label-free electrochemical detection of pathogenic bacteria

Lucen Li, Qinhan Chen, Aobin Han, Qiaolin Guo, Minghui Wang, Wei Song, Jing Lin and Gefei Li

Analyst, 2026, 151, 116
DOI: 10.1039/D5AN01136A

Thiol-selective native grafting from polymerization for the generation of protein–polymer conjugates

Melina I. Feldhof, Sandro Sperzel, Lorand Bonda, Susanne Boye, Adam B. Braunschweig, Ulla I. M. Gerling-Driessen and Laura Hartmann

Chem. Sci., 2024, 15, 16768
DOI: 10.1039/D4SC04818K

Recent developments in antimicrobial polymers for biofilm inhibition

Gillian A. Kropp, Cassell N. McMillian, Jonathan D. Mase, Sanjana Kandagiri, Elizabeth S. Nowak and Michael D. Schulz

Chem. Commun., 2026, 62, 7645
DOI: 10.1039/D5CC06617D

Hydrophilic and clickable poly(oxa)norbornenes for multivalent lectin binding

Clément Gonnot, Mathieu Scalabrini, Benoit Roubinet, Fabien Boeda, David Deniaud, Ludovic Landemarre, Sébastien G. Gouin, Laurent Fontaine and Véronique Montembault

Polym. Chem., 2025, 16, 3310
DOI: 10.1039/D5PY00342C

Inherent antibacterial properties of mannose-containing polynorbornene glycomaterials

Brady A. Hall, Ophelia J. Wadsworth, Logan M. Breiner, Jacob C. Chappell, Andrew S. Brenner, Jennifer P. McCord, Andrew N. Lowell and Michael D. Schulz

Chem. Commun., 2025, 61, 4539
DOI: 10.1039/D5CC00590F

Multivalent 2D- and 3D-nanogels as carbohydrate-lectin binders

Ann-Cathrin Schmitt, Maximilian Braun, Stefanie Wedepohl, Mathias Dimde, Philip Nickl, Kai Ludwig, Tatyana L. Povolotsky and Rainer Haag

Biomater. Sci., 2025, 13, 4400
DOI: 10.1039/D5BM00286A

Translating magnetic fluid hyperthermia toward lung cancer treatment

Malgorzata Sikorska, Magdalena Bamburowicz-Klimkowska, Monika Ruzycka-Ayoush, Anna M. Nowicka, Agata Kowalczyk, Artur Kasprzak, Grzegorz Domanski, Barbara Wagner, Monika Prochorec-Sobieszek, Marzena Cabaj, Anna Szumera-Cieckiewicz, Maciej Glogowski, Andrzej Cieszanowski and Ireneusz P. Grudzinski

Nanoscale, 2026, 18, 7564
DOI: 10.1039/D5NR05036G

Effect of molar mass of poly(2-oxazoline) based glycopolymers on lectin binding

Caitlin L. A. Nutting, James Lefley, Zivani Varanaraja, Gokhan Yilmaz and C. Remzi Becer

Polym. Chem., 2024, 15, 5023
DOI: 10.1039/D4PY01135J

Glycan-mediated adhesion mechanisms in antibiotic-resistant bacteria

Clara Dessenne, Christophe Mariller, Olivier Vidal, Isabelle Huvent, Yann Guerardel, Elisabeth Elass-Rochard and Yannick Rossez

BBA Advances, 2025, 7, 100156
DOI: 10.1016/j.bbadva.2025.100156

AIE‐Powered Nanosoldiers for Precision Disruption of Biofilm's Extracellular Defense in Infection Treatment

Wei Lu, Zhurun Fang, Xiaolong Zhu, Yan Xu, Ben Zhong Tang, Mingqian Wang, Yuanyuan Li, Yi Zhang and Ming Zhang

Adv Funct Materials, 2026, 36
DOI: 10.1002/adfm.202510949

Design of Glycopolymers for Controlling the Interactions with Lectins

Masanori Nagao, Hikaru Matsumoto and Yoshiko Miura

Chemistry An Asian Journal, 2023, 18
DOI: 10.1002/asia.202300643

Glycan-Presenting Coacervates Derived from Charged Poly(active esters): Preparation, Phase Behavior, and Lectin Capture

Michele Denise Illmann, Lea Schäfl, Felicitas Drees, Laura Hartmann and Stephan Schmidt

Biomacromolecules, 2023, 24, 2532
DOI: 10.1021/acs.biomac.3c00046

Sugars in Antimicrobial Polymers – The Impact of Sugar‐Lectin Binding in Membrane Interaction of Cationic Glycopolymers

Alain M. Bapolisi, Steffen Tank, Anne‐Catherine Lehnen, Antje Stindt, Rujuta Athavale, Jan A. M. Kurki, Sany Chea, Sophia Rosencrantz, Ruben R. Rosencrantz, Katja M. Arndt and Matthias Hartlieb

Adv Materials Inter, 2025, 12
DOI: 10.1002/admi.202500273

Antibacterial MoS2/CaCO3 Nanoplatform for Combined Photothermal, Photodynamic, and Nitric Oxide Therapy

Weihao Jin, Yujia Wu, Wanzhen Li, Jun Wang, Kai Yang, Ping Song, Longbao Zhu, Weiwei Zhang, Lin Gui and Fei Ge

ACS Appl. Nano Mater., 2023, 6, 18880
DOI: 10.1021/acsanm.3c03267

Glycosylated stimuli responsive polyacrylamide microspheres with in-situ formed AgNPs for bacterial capture, detection and killing

Juby K. Ajish, Pramodh N Rao, Sourav Bhakta, Swathi Kota and K.S. Ajish Kumar

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 696, 134305
DOI: 10.1016/j.colsurfa.2024.134305

Two birds with one stone: A multi-functional nanoplatform for sensitive detection and real-time inactivation of pathogenic bacteria with NIR-triggered PTT/PDT

Xianqing Huang, Yana Fu, Yicheng Guo, Yuzheng Cai, Tiange Li, Peijun Zhao, Yan Ma, Lianjun Song and Tianlin Wang

Chemical Engineering Journal, 2024, 481, 148649
DOI: 10.1016/j.cej.2024.148649

Glycoengineered mesenchymal stem cell exosomes with dual-tissue targeting ameliorate glycolipid metabolism in type 2 diabetes mellitus

Yingyue Xiang, Jidong Liu, Xue Liu, Nan Zang, Mengmeng Yang, Liming Wang, Jia Song, Jun Chen, Kewei Wang, Longqing Xia, Xinguo Hou, Li Chen, Qin He and Fuqiang Liu

Chemical Engineering Journal, 2026, 532, 174202
DOI: 10.1016/j.cej.2026.174202

Sulfated Glycosaminoglycans as Inhibitors for Chlamydia Infections: Molecular Weight and Sulfation Dependence

Sebastian Wintgens, Janita Müller, Felicitas Drees, Dominik Spona, Lorand Bonda, Laura Hartmann, Johannes H. Hegemann and Stephan Schmidt

Macromolecular Bioscience, 2025, 25
DOI: 10.1002/mabi.202400443

Recent advances in designing antimicrobial polymers with diverse uptake and killing mechanisms

Zhangyong Si and Mary B. Chan-Park

Progress in Polymer Science, 2026, 174, 102080
DOI: 10.1016/j.progpolymsci.2026.102080

Morphological Transformation and Surface Engineering of Glycovesicles Driven by Bioinspired Hydrogen Bonds of Nucleobases

Caiyun Yang, Yixuan Du, Qiaoran Li, Xinru Gao, Peng Zha, Wanli Zhan, Ketao Liu, Feihu Bi, Zan Hua and Guang Yang

ACS Macro Lett., 2024, 13, 468
DOI: 10.1021/acsmacrolett.4c00037

Coassembled Perylene–Carbohydrate Conjugates Exert Antibiotic‐Free Antibacterial Effects and Enhance the Effects of Photothermal Therapy by Targeting LecA/LecB Lectins

Jian‐Xing Yang, Fangqian Yin, Hai‐Qing Li, Gao‐Juan Lin, Wen‐Juan Yin, Xiao‐Liu Li and Ke‐Rang Wang

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202404859

Synthesis of Dual‐Responsive Amphiphilic Glycomacromolecules: Controlled Release of Glycan Ligands via pH and UV Stimuli

Nicholas Jäck, Arne Hemming and Laura Hartmann

Macromol. Rapid Commun., 2024, 45
DOI: 10.1002/marc.202400439

Fluorescent Polymeric Materials for Bacterial Interaction and Detection

Dilani Chathumalee, Stephen J. Butler and Amanda K. Pearce

Macro Chemistry & Physics, 2026, 227
DOI: 10.1002/macp.202500482

Glyco-nanomaterials as a therapeutic target in drug delivery and biomedicine: A review

Akanksha D. Dessai, Akhil Nair, Nandakumar Selvasudha, Sanjay Garg and Usha Y. Nayak

International Journal of Biological Macromolecules, 2025, 329, 147830
DOI: 10.1016/j.ijbiomac.2025.147830

Facile Preparation of Carbohydrate‐Containing Adjuvants Based on Self‐Assembling Glycopeptide Conjugates

Biao Wang, Sijin Liu, Haoting Li, Weidong Dong, Haiyun Liu, Jun Zhang, Chao Tian and Suwei Dong

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202309140

Controlling the Sulfation Density of Glycosaminoglycan Glycopolymer Mimetics Enables High Antiviral Activity against SARS-CoV-2 and Reduces Anticoagulant Activity

Miriam Hoffmann, Lorand Bonda, Ines Fels, Darisuran Anhlan, Eike Hrincius, Derik Hermsen, Stephan Ludwig, Mario Schelhaas, Nicole L. Snyder and Laura Hartmann

Biomacromolecules, 2025, 26, 5169
DOI: 10.1021/acs.biomac.5c00576

Lectin-mediated adhesion: Testing of tailor-made cellulose derivatives with ConA and live E. coli bacteria

Carina Spormann, Tobias Dorn, Stefan Schwaiger, Sönke Sdunnus, Andreas Koschella, Hanspeter Kählig, Thomas Heinze, Thisbe K. Lindhorst and Tanja M. Wrodnigg

Bioorganic & Medicinal Chemistry, 2025, 127, 118236
DOI: 10.1016/j.bmc.2025.118236

Sialylated porphyrins optimized as anti-infective agents against SARS-CoV-2 variants

Vivian Lioret, Constant Gillot, Marie Hologne, Jenny Ha, Dmytro Strilets, Laurent Lubrano Di Scampamorte, Laurent Gillet, Jonathan Douxfils and Stéphane P. Vincent

Bioorganic Chemistry, 2026, 170, 109519
DOI: 10.1016/j.bioorg.2026.109519

Total Synthesis of Conjugation-Ready Hyperbranched Pentasaccharide of Clavibacter phaseoli VKM Ac-2641T by [Au]/[Ag] Catalysis

Pratim Kumar Das and Srinivas Hotha

Org. Lett., 2024, 26, 6709
DOI: 10.1021/acs.orglett.4c02386

Harnessing aptamers for the biosensing of cell surface glycans – A review

Sirui Liu, Furong Zhao, Ke Xu, Min Cao, Muhammad Sohail, Bingzhi Li and Xing Zhang

Analytica Chimica Acta, 2024, 1288, 342044
DOI: 10.1016/j.aca.2023.342044

Glycopolymer-engineered materials and surfaces: Immobilized strategies and biomedical applications

Gefei Li, Juan Mo, Yi Deng, Wenhuan Zhong, Qinhan Chen and Xin-Shan Ye

Chinese Chemical Letters, 2025, 111969
DOI: 10.1016/j.cclet.2025.111969

Glycomimetic antagonists of BC2L-C lectin: insights from molecular dynamics simulations

Giulia Antonini, Monica Civera, Kanhaya Lal, Sarah Mazzotta, Annabelle Varrot, Anna Bernardi and Laura Belvisi

Front. Mol. Biosci., 2023, 10
DOI: 10.3389/fmolb.2023.1201630

Glycopolymers Prepared by Alternating Ring-Opening Metathesis Polymerization Provide Access to Distinct, Multivalent Structures for the Probing of Biological Activity

Luz C. Mendez, Francis O. Boadi, Mitchell Kennedy, Surita R. Bhatia and Nicole S. Sampson

ACS Bio Med Chem Au, 2024, 4, 214
DOI: 10.1021/acsbiomedchemau.4c00018

Advances in natural biomacromolecule-based Janus materials: preparation, applications and future prospects in food science

Ying Xu, Xuan Tao, Liubin Li, Yao Chen, Rong He, Xingrong Ju and Zhigao Wang

Critical Reviews in Food Science and Nutrition, 2026, 66, 1123
DOI: 10.1080/10408398.2025.2540050

Natural mannose-containing glycans as gut modulators: A mechanistic and translational perspective

Wenqi Shang, Min Wang, Fangfang Tian, Guozheng Wei, Meng Zhou, Bowen Yan, Chenhuan Lai, Caoxing Huang and Qiang Yong

Trends in Food Science & Technology, 2026, 172, 105709
DOI: 10.1016/j.tifs.2026.105709

Analysis of specific recognition of glycopolymers-lectins using fluorescence titration: Determination of binding constants

Wen-Tao Liu, Yong-Li Zheng, Li-Li Zhu, Lan-Xue Zhao, Jian-Rong Xu and Jing Quan

Materials Today Communications, 2025, 43, 111554
DOI: 10.1016/j.mtcomm.2025.111554

Sequence-defined polymers for biomedical applications

Nicholas Jäck, Sören Nagel and Laura Hartmann

Progress in Polymer Science, 2025, 167, 101993
DOI: 10.1016/j.progpolymsci.2025.101993

Pathogen‐binding nanoparticles to inhibit host cell infection by heparan sulfate and sialic acid dependent viruses and protozoan parasites

Adrian Najer

Smart Medicine, 2024, 3
DOI: 10.1002/SMMD.20230046

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

Alisa Kayser, Kai Klein, Daria Babushkina, Anne Sakse, Gisele Mouafo Kenne, Ulla I.M. Gerling‐Driessen, Monir Tabatabai, Matthias Epple and Laura Hartmann

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202500497

A “sweeter” approach to cancer immunotherapy: Glycopolymers as diverse tools for immune modulation

Kenneth Hulugalla, Oluwatosin David Abodunrin, Joshua Anderson, Adam E. Smith and Thomas Werfel

Journal of Controlled Release, 2025, 388, 114372
DOI: 10.1016/j.jconrel.2025.114372

Fe0-MAP Prepared Glycosurfaces for Selective Cell Capture: From Adherent to Suspended Cells

Yu Duan, Xiaoliang Ma, Jiangping Guo, Fangjian Shan, Yuchun Pan, Yuru Chen, Hong Chen and Gaojian Chen

ACS Appl. Mater. Interfaces, 2024
DOI: 10.1021/acsami.4c11627

Molecular Engineering-Driven Self-Assembled Nanotheranostic System for Mannose-Targeted Synergistically Enhanced Photothermal-Photodynamic Precision Therapy in Colorectal Cancer

Yingying Zhong, Yuanyuan Liu and Xin Liu

ACS Appl. Mater. Interfaces, 2025
DOI: 10.1021/acsami.5c23470

Chemical tools to study and modulate glycan-mediated host-bacteria interactions

Divya Bhargava, Aniqa Chowdhury and Danielle H. Dube

Current Opinion in Chemical Biology, 2025, 87, 102603
DOI: 10.1016/j.cbpa.2025.102603

Facile Preparation of Carbohydrate‐Containing Adjuvants Based on Self‐Assembling Glycopeptide Conjugates

Biao Wang, Sijin Liu, Haoting Li, Weidong Dong, Haiyun Liu, Jun Zhang, Chao Tian and Suwei Dong

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202309140

Sweet Janus Particles: Multifunctional Inhibitors of Carbohydrate-Based Bacterial Adhesion

Serap Üclü, Claudia Marschelke, Felictas Drees, Markus Giesler, Dimitri Wilms, Thorben Köhler, Stephan Schmidt, Alla Synytska and Laura Hartmann

Biomacromolecules, 2024, 25, 2399
DOI: 10.1021/acs.biomac.3c01333

Glycopolymeric Micellar Nanoparticles for Platelet-Mediated Tumor-Targeted Delivery of Docetaxel for Cancer Therapy

Yan Zhang, Yi Li, Jieyu Gu, Jun Wu, Yongxin Ma, Guodong Lu, Mihail Barboiu and Jinghua Chen

ACS Appl. Mater. Interfaces, 2024, 16, 44528
DOI: 10.1021/acsami.4c09548

COVID-19 and blood group-related antigens: can natural anti-carbohydrate antibodies provide innate protection from symptomatic SARS-CoV-2 infection?

Tasnuva Ahmed, Adrien Breiman, Marjahan Akhtar, Golap Babu, Nasrin Pervin, Md Golam Firoj, Afroza Akter, Firdausi Qadri, Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Jacques Le Pendu and Nathalie Ruvoën-Clouet

Front. Med., 2025, 12
DOI: 10.3389/fmed.2025.1554785

Structure-Controllable and Mass-Produced Glycopolymersomes as a Template of the Carbohydrate@Ag Nanobiohybrid with Inherent Antibacteria and Biofilm Eradication

Hanchen Wei, Caiyun Yang, Feihu Bi, Bang Li, Rui Xie, Deshui Yu, Shuzhen Fang, Zan Hua, Qingqing Wang and Guang Yang

Biomacromolecules, 2024, 25, 315
DOI: 10.1021/acs.biomac.3c01003

Glycopolymers as a Tool for Specific Surface Modification of Polymeric Biomaterials

Joachim Storsberg, Sophia Rosencrantz and Ruben R. Rosencrantz

Biophysica, 2026, 6, 23
DOI: 10.3390/biophysica6020023

Glycopolymer nanomicelles: pH-responsive drug delivery, endocytosis pathway, autophagy behavior, and the effect of autophagy inhibitors

Zhao Wang, Jingjing Sun, Lin Jia and Ruilong Sheng

J Mater Sci: Mater Med, 2025, 36
DOI: 10.1007/s10856-024-06837-4

Host-pathogen hybrid glycocalyx mimicking lipid nanoparticles induce trained immunity as a promising platform for universal vaccines

Xueying Tang, Yuejia Sun, Jiashuo Zhang, Hongtao Li, Yuanyuan Lu, Lei Yuan, Haopeng Li, Xinrong Liu, Yanzhi Song, Yu Zhang and Yihui Deng

Journal of Controlled Release, 2026, 390, 114489
DOI: 10.1016/j.jconrel.2025.114489

Fucose‐Based Glycopolymeric Nanomicelles for Activated Platelet‐Targeted Photothermal Thrombolysis

Minzhi Song, Wenxi Yang, Lingxin Peng, Changan Ren, Jinghua Chen and Yan Zhang

ChemBioChem, 2025, 26
DOI: 10.1002/cbic.202500253