Single-atom nanozyme-based catalytic ROS clearance for efficiently alleviating eczema

Zhen Wan, Yadong Zhe, Jiarong Li, Qingshan Liu, Danqi Ding, Shaofang Zhang, Shuangjie Liu, Hao Wang, Jiang Yang, Xin Sun, Huanhuan Qiao and Xiaoyu Mu

J. Mater. Chem. B, 2025, 13, 1969
DOI: 10.1039/D4TB02316A

Design and optimization of a Cu-MOF@graphene oxide nanozyme for point-of-care colorimetric determination of sarcosine and H2O2

Martin N. Saad, Amr M. Mahmoud, Sawsan M. Amer, Ibrahim M. El-Sherbiny and Hoda M. Marzouk

RSC Adv., 2026, 16, 24916
DOI: 10.1039/D6RA01609J

Two-dimensional metal organic frameworks in cancer treatment

Chao Wang and Shan Zhang

Mater. Horiz., 2024, 11, 3482
DOI: 10.1039/D4MH00068D

Design of carbon dots as nanozymes to mediate redox biological processes

Qian He and Liyun Zhang

J. Mater. Chem. B, 2023, 11, 5071
DOI: 10.1039/D2TB02259A

Reduction of intracellular oxidative stress with a copper-incorporated layered double hydroxide

Adél Szerlauth, Tamara Madácsy, Gergely Ferenc Samu, Péter Bíró, Miklós Erdélyi, Gábor Varga, Zhi Ping Xu, József Maléth and István Szilágyi

Chem. Commun., 2024, 60, 1325
DOI: 10.1039/D3CC05762C

Implications of non-native metal substitution in carbonic anhydrase – engineered enzymes and models

Dyuti Bhandary, Sam P. de Visser and Gourab Mukherjee

Chem. Commun., 2025, 61, 612
DOI: 10.1039/D4CC05003G

Recent trends in nanozymes design: from materials and structures to environmental applications

Camilo A. S. Ballesteros, Luiza A. Mercante, Augusto D. Alvarenga, Murilo H. M. Facure, Rodrigo Schneider and Daniel S. Correa

Mater. Chem. Front., 2021, 5, 7419
DOI: 10.1039/D1QM00947H

Manganese-doped iron coordination polymer nanoparticles with enhanced peroxidase-like activity for colorimetric detection of antioxidants

Chenghui Zhang, Xingfeng Zhang, Yu Ye, Pengjuan Ni, Chuanxia Chen, Wendong Liu, Bo Wang, Yuanyuan Jiang and Yizhong Lu

Analyst, 2022, 147, 238
DOI: 10.1039/D1AN01953H

Tuning atomic-scale sites in metal–organic framework-based nanozymes for sensitive biosensing

Yating Wen, Weiqing Xu, Liuyong Hu, Miao Xu, Wenling Gu, Hongcheng Sun and Chengzhou Zhu

Sens. Diagn., 2023, 2, 1376
DOI: 10.1039/D3SD00177F

Dual mimic enzyme properties of Fe nanoparticles embedded in two-dimensional carbon nanosheets for colorimetric detection of biomolecules

Jie Wang, Chenglong Zhao, Feijin Zhou, Hui Lu, Zhenhong Huang, Cheng Yao and Chan Song

Analyst, 2023, 148, 146
DOI: 10.1039/D2AN01704K

Enhancing the peroxidase-like activity of MIL-88B by ligand exchange with polydopamine

Changzhi Hu, Yuhao Xiong, Ling Liang, Weiyuan Zuo, Fanggui Ye and Shulin Zhao

Dalton Trans., 2022, 51, 2262
DOI: 10.1039/D1DT03832J

Unusual oxidase-mimetic catalytic performance surpassing peroxidase in amorphous CoOx: underlying mechanism and toward a novel H2O2-related detection paradigm

Zhijian Bu, Jinjin Liu, Zheng Tang, Hao Liang, Qinqin Bai, Shuangquan Liu and Xiangheng Niu

Chem. Commun., 2025, 61, 7672
DOI: 10.1039/D5CC01429H

A new and highly efficient CuMOF-based nanoenzyme and its application to the aptamer SERS/FL/RRS/Abs quadruple-mode analysis of ultratrace malachite green

Shuxin Chen, Yue Liu, Zhiyu Qin, Guiqing Wen and Zhiliang Jiang

Analyst, 2024, 149, 1179
DOI: 10.1039/D3AN01902K

Tri-responsive multifunctional metal–organic framework (MuF-MOF) nanozyme-based sensors

M. Nejati, M. Kalhori, Z. Zangouei, S. Dastani, K. Dashtian, R. Zare-Dorabei and K. Kerman

J. Mater. Chem. A, 2026, 14, 11145
DOI: 10.1039/D5TA08531D

A petal-shaped MOF assembled with a gold nanocage and urate oxidase used as an artificial enzyme nanohybrid for tandem catalysis and dual-channel biosensing

Zejun Sun, Yujiao Sun, Meng Yang, Hui Jin and Rijun Gui

Nanoscale, 2021, 13, 13014
DOI: 10.1039/D1NR02688G

Advances in oxygenation nanozymes for overcoming diabetic ulcers

Sumi Choi, Minjeong Kim, Minjin Kim and Su-Hwan Kim

Biomater. Sci., 2025, 13, 3498
DOI: 10.1039/D5BM00340G

Metal–organic framework-based nanozymes: types, activity regulation and analytical applications

Mingyue Xie, Shidun Chen, Ke Chen, Qinghuan Gao, Jiake Li, Yiying Hao and Xingyue Lu

Analyst, 2025, 150, 3011
DOI: 10.1039/D5AN00365B

Recent progress in nanozyme-based sensors for ion detection: strategies, trends, and challenges

Xin Li, Jinjin Liu, Jia Chen, Hongdeng Qiu and Xiangheng Niu

Sens. Diagn., 2023, 2, 307
DOI: 10.1039/D2SD00233G

Correlation between cation distribution and catalytic production of free radicals in mixed ferrite nanoparticles

Martín Eduardo Saleta, Teobaldo Enrique Torres, Dina Tobia, Danilo Oliveira de Souza, Giuliana Aquilanti, Elin Lilian Winkler and Enio Lima

J. Mater. Chem. C, 2025, 13, 16120
DOI: 10.1039/D5TC01732G

Emerging 2D MXene-conjugated nanoarchitectures for nanozymes: current advances and future frontiers in biochemical sensing technologies

Ramar Rajamanikandan, Kandasamy Sasikumar and Heongkyu Ju

Environ. Sci.: Nano, 2025, 12, 4796
DOI: 10.1039/D5EN00710K

Diazo-reaction based dual-mode colorimetric-electrochemical sensing of nitrite in pickled food

Yixin Pan, Jing Jiang and Xianwen Kan

Analyst, 2023, 148, 4869
DOI: 10.1039/D3AN01196H

Immobilizing nanozymes on 3D-printed metal substrates for enhanced peroxidase-like activity and trace-level glucose detection

Paramita Koley, Ranjithkumar Jakku, Tayebeh Hosseinnejad, Selvakannan Periasamy and Suresh K. Bhargava

Nanoscale, 2024, 16, 5561
DOI: 10.1039/D3NR05427F

3D-printed hollow microneedle-based electrochemical sensor for wireless glucose monitoring

Chuchu Chen, Yonghao Fu, Yuehe Lin, Yun Liu, Dan Du and Kaiyan Qiu

Analyst, 2026, 151, 1182
DOI: 10.1039/D5AN01058F

Development of a colorimetric sensor based on a peroxidase-like Cu,Fe-TCPP metal–organic framework for detection of fleroxacin

Xin Yao, Xiao Liang, Wenbo Zhao, Jinrong He, Yao Bai and Zitao Zhong

J. Mater. Chem. C, 2025, 13, 17616
DOI: 10.1039/D5TC02076J

Selective and sensitive on-site colorimetric detection of 4,4′-isopropylidenediphenol using non-enzymatic molecularly imprinted graphitic carbon nitride hybrids in milk and water samples

M. Komal, J. Vinoth Kumar, R. Arulmozhi, M. Sherlin Nivetha, S. Pavithra and N. Abirami

New J. Chem., 2023, 47, 9087
DOI: 10.1039/D3NJ01241G

Development of nanozyme based sensors as diagnostic tools in clinic applications: a review

Waris, Abul Hasnat, Shumaila Hasan, Sayfa Bano, Saima Sultana, Alex Omo Ibhadon and Mohammad Zain Khan

J. Mater. Chem. B, 2023, 11, 6762
DOI: 10.1039/D3TB00451A

Keratin-inorganic hybrid nanoflowers decorated with Fe3O4 nanoparticles as enzyme mimics for colorimetric detection of glucose

Peiyu Li, Jing Zheng, Jingli Xu and Min Zhang

Dalton Trans., 2021, 50, 14753
DOI: 10.1039/D1DT02301B

Triggering gold nanoparticles formation on a quartz surface by nanosecond pulsed laser irradiation

P. A. Mercadal, S. D. García Schejtman, F. P. Cometto, A. V. Veglia and E. A. Coronado

RSC Adv., 2021, 11, 22419
DOI: 10.1039/D1RA01991K

Recent advances on nanomaterial-based glutathione sensors

Saman Bagherpour and Lluïsa Pérez-García

J. Mater. Chem. B, 2024, 12, 8285
DOI: 10.1039/D4TB01114G

Construct an “immunogenic cell death” amplifier based on Fe-MOFs by accelerating Fe(iii) reduction strategies for integration of tumor diagnosis, treatment, and prevention

Kexin Luo, Sasha You, Jingyu Chen, Bin Chi, Kai Zhang, Jian Tian, Xiyue Feng, Wang Ye, Yingxi Wang, Ling Li, Xiaolan Yu and Jing Wang

J. Mater. Chem. B, 2025, 13, 7691
DOI: 10.1039/D5TB00686D

Prudently designed Se@fMWCNT as a peroxidase mimicking nanozyme for distinctive electrochemical detection of H2O2 and glutathione

Vadakke Purakkal Sruthi and Sellappan Senthilkumar

J. Mater. Chem. C, 2024, 12, 8924
DOI: 10.1039/D4TC01231C

ROS-scavenging biomaterials for periodontitis

Enni Chen, Tianyou Wang, Yuan Tu, ZhiYuan Sun, Yi Ding, Zhipeng Gu and Shimeng Xiao

J. Mater. Chem. B, 2023, 11, 482
DOI: 10.1039/D2TB02319A

In situ generated Fe3C embedded Fe–N-doped carbon nanozymes with enhanced oxidase mimic activity for total antioxidant capacity assessment

Rui Li, Xiaohong Qiao, Huijun Ma, Hanmei Li, Cong Li and Lihua Jin

J. Mater. Chem. B, 2022, 10, 3311
DOI: 10.1039/D1TB02695J

Boosting the oxidase-mimicking activity of metal–organic framework nanozymes via heteroatom modulation in the organic linkers

Yan Wei, Qiming Yan, Zizhe Yan, Jinle Yang, Liuhan Zhang, Feng Li and Dangqiang Zhu

Chem. Commun., 2026, 62, 8216
DOI: 10.1039/D6CC01013J

A fast phosphate colorimetric sensor based on MoS2/UiO-66 (Fe/Zr) nanocomposites as oxidase-/peroxidase-like nanoenzymes

Baocan Zhu, Fengyang Zhao, Pingping Hao, Hongguan Yu, Renxia Jiang, Qingyun Liu and Zhenxue Liu

New J. Chem., 2021, 45, 19671
DOI: 10.1039/D1NJ03149J

Research progress of metal–organic framework nanozymes in bacterial sensing, detection, and treatment

Yiwei An, Xuankun Fang, Jie Cheng, Shuiyuan Yang, Zuanguang Chen and Yanli Tong

RSC Med. Chem., 2024, 15, 380
DOI: 10.1039/D3MD00581J

The bi-metallic MOF-919 (Fe–Cu) nanozyme capable of bifunctional enzyme-mimicking catalytic activity

Sivasankar Kulandaivel, Chia-Her Lin and Yi-Chun Yeh

Chem. Commun., 2022, 58, 569
DOI: 10.1039/D1CC05908D

Biomimetic CuO/ZTF-8 nanozyme-based neoteric sensor for the selective detection of superoxide anions

Vadakke Purakkal Sruthi, Shafeeq Sarfudeen, Tamas Panda, Kathavarayan Thenmozhi and Sellappan Senthilkumar

J. Mater. Chem. A, 2025, 13, 8343
DOI: 10.1039/D4TA07300B

A label-free electrochemical platform based on a thionine functionalized magnetic Fe–N–C electrocatalyst for the detection of microRNA-21

Xiangyu Ma, Kun Qian, Onome Ejeromedoghene, Martha Kandawa-Schulz, Wei Song and Yihong Wang

Analyst, 2021, 146, 4557
DOI: 10.1039/D1AN00430A

Advances in the application of metal–organic framework nanozymes in colorimetric sensing of heavy metal ions

Li Zhang, Xiaoya Bi, Xiaohong Liu, Yi He, Libo Li and Tianyan You

Nanoscale, 2023, 15, 12853
DOI: 10.1039/D3NR02024J

Nanozymes with versatile redox capabilities inspired in metalloenzymes

Rocío López-Domene, Krishan Kumar, Jose Eduardo Barcelon, Gabriela Guedes, Ana Beloqui and Aitziber L. Cortajarena

Nanoscale, 2023, 15, 16959
DOI: 10.1039/D3NR03443G

Recent advances in nanozymes for organophosphorus pesticide detection in food

Xueer Lin, Yanyan Huang, Jiahui Zou, Guancheng Zhu, Linfeng Pang and Yuqi Chen

Chem. Commun., 2025, 61, 14510
DOI: 10.1039/D5CC03464G

Quasi-Cu-MOFs: highly improved water stability and electrocatalytic activity toward H2O2 reduction among pristine 3D MOFs

Duanping Sun, Linxi Chen, Lizhu Zeng, Xianhua Shi and Jing Lu

J. Mater. Chem. A, 2023, 11, 31
DOI: 10.1039/D2TA05833B

Enzyme-like activity of cobalt-MOF nanosheets for hydrogen peroxide electrochemical sensing

Arismendy Portorreal-Bottier, Silvia Gutiérrez-Tarriño, Juan José Calvente, Rafael Andreu, Emilio Roldán, Pascual Oña-Burgos and José Luis Olloqui-Sariego

Sensors and Actuators B: Chemical, 2022, 368, 132129
DOI: 10.1016/j.snb.2022.132129

Metal–Organic Framework-Enabled Sustainable Agrotechnologies: An Overview of Fundamentals and Agricultural Applications

Zhaowen Cui, Yuechun Li, Olga V. Tsyusko, Jianlong Wang, Jason M. Unrine, Gehong Wei and Chun Chen

J. Agric. Food Chem., 2024
DOI: 10.1021/acs.jafc.4c00764

Luminescent Nanozyme-Based Sensors for Bacteria Detection

D. S. Chumakov, S. S. Evstigneeva and O. I. Guliy

Appl Biochem Microbiol, 2024, 60, 1022
DOI: 10.1134/S0003683824606139

Bimetallic MOFs-derived four-in-one CeCuOx/C nanozyme and its application for colorimetric detection of cysteine based on oxidase mimics

Wen-Xuan Jia, Ming-Ming Tao, Xin-Yu Wang, Yan-Feng Huang and Ying Li

Talanta Open, 2024, 9, 100292
DOI: 10.1016/j.talo.2024.100292

A facile nanozyme-based colorimetric method to realize the quantitative and specific detection of casein phosphopeptides in food samples

Zhiyi Zhang, Xiaoxiao Yu, Xin Peng, Wei Qi and Mengfan Wang

Talanta, 2024, 276, 126212
DOI: 10.1016/j.talanta.2024.126212

Nanozymes: a dual approach to bacterial colorimetric and luminescent detection and to bacterial pathogen killing

Olga I. Guliy, Daniil S. Chumakov, Stella S. Evstigneeva, Qingyun Liu and Elena G. Zavyalova

Biosensors and Bioelectronics, 2025, 288, 117835
DOI: 10.1016/j.bios.2025.117835

Redox interference-free bimodal paraoxon sensing enabled by an aggregation-induced emission nanozyme catalytically hydrolyzing phosphoesters specifically

Hengjia Zhu, Bangxiang Liu, Jianming Pan, Lizhang Xu, Jinjin Liu, Panwang Hu, Dan Du, Yuehe Lin and Xiangheng Niu

Biosensors and Bioelectronics, 2025, 267, 116756
DOI: 10.1016/j.bios.2024.116756

Microenvironment engineering of MOFzymes for biomedical applications

Xiaoping Zhao, Rui Gao, Heng Sun, Peng Chen, Haixue Zheng and Lingjie Meng

Coordination Chemistry Reviews, 2025, 533, 216539
DOI: 10.1016/j.ccr.2025.216539

Porphyrin-Containing Metallacage with Precise Active Sites and Super Long-Term Stability as a Specific Peroxidase Mimic for Versatile Analyte Determination

Chenyu Zhou, Yunting Zeng, Zhimin Song, Quanyi Liu, Yu Zhang, Ming Wang and Yan Du

Anal. Chem., 2022, 94, 13261
DOI: 10.1021/acs.analchem.2c03206

Two Novel Pyrene Tetra-Sulfonate Europium Coordination Polymers: Structure Formation Mechanism Analysis and Sequential Modulation Strategy

Haoran Li, Xiaolian Sun, Jiaju Fu and Wenlei Zhu

Crystals, 2022, 12, 1818
DOI: 10.3390/cryst12121818

Reticular framework materials-enhanced biomimetic cascade catalysis systems for boosting advanced biosensing

Yiyi Zhang, Junyu Pan, Xiru Zhang, Xiaorong Liu, Manyan Qiu, Feng Zhao, Wei Zhang, Xianlong Zhang and Yujun Jiang

Coordination Chemistry Reviews, 2025, 534, 216571
DOI: 10.1016/j.ccr.2025.216571

Ultrasensitive Detection of Bacteria Using a 2D MOF Nanozyme-Amplified Electrochemical Detector

Wen-Chao Hu, Jie Pang, Sudip Biswas, Kang Wang, Chen Wang and Xing-Hua Xia

Anal. Chem., 2021, 93, 8544
DOI: 10.1021/acs.analchem.1c01261

Emulsion-templated construction of enzyme-nanozyme integrated hierarchically porous hydrogels for smartphone-assisted pesticide biosensing

Hengjia Zhu, Peng Liu, Lizhang Xu, Mengzhu Wang, Jianming Pan and Xiangheng Niu

Chemical Engineering Journal, 2022, 433, 133669
DOI: 10.1016/j.cej.2021.133669

Ce/Zr-MOF with Dual Cycle Synergistic Catalysis Pathway Enabling Enhanced Peroxidase-like Performance for Wearable Hydrogel Patch Visualization Sensing Platform

Ying Liu, Xilong Zhou, Weiran Zhu, Chen Chen, Cunhao Fan, Lijun Ding and Kun Wang

Inorg. Chem., 2023, 62, 15022
DOI: 10.1021/acs.inorgchem.3c01874

Broken but not beaten: Unraveling the biotransformation fate of Mn@PCN224 nanozymes and its influence on enzymatic activity and safety at the human placenta in vitro

Nikolaos Tagaras, Haihan Song, Giacomo Reina, Sandro Lehner, Vera M. Kissling, Alexander Gogos, Weijun Tong and Tina Buerki-Thurnherr

Nano Today, 2025, 65, 102857
DOI: 10.1016/j.nantod.2025.102857

Dual-Function Janus Nanozymes for Performance Evaluation and Application in a Surrogate Virus Neutralization Test with Vaccinated Samples

Su-Heon Kwak, Dae Gwin Jeong, Hyun Kyong Shon, Dong-Ho Kim, Tae Geol Lee, Jung-Sub Wi and Hee-Kyung Na

ACS Appl. Mater. Interfaces, 2023, 15, 55975
DOI: 10.1021/acsami.3c12251

Synthesis of cobalt selenide composite material: A novel platform of the electrochemical sensor for sensitive determination of Upadacitinib

Asena Ayse Genc, Wiem Bouali, Nesrin Buğday, Sedat Yaşar and Nevin Erk

Electrochimica Acta, 2024, 487, 144164
DOI: 10.1016/j.electacta.2024.144164

Array of Manganese-Based Bimetallic Metal–Organic-Framework Nanozymes with Enhanced Oxidase-like Catalytic Activity Can Simultaneously Identify and Measure Antioxidants

Oldouz Heidary, Hossein Ashrafi, Morteza Akhond and Bahram Hemmateenejad

Anal. Chem., 2025, 97, 4860
DOI: 10.1021/acs.analchem.4c03942

Biomedical Applications of Functionalized Composites Based on Metal–Organic Frameworks in Bone Diseases

Chenxi Yun, Zhe Yuan, Rim El Haddaoui-Drissi, Ruitong Ni, Yunyun Xiao, Zhenhui Qi, Jie Shang and Xiao Lin

Pharmaceutics, 2025, 17, 757
DOI: 10.3390/pharmaceutics17060757

Porous Oxyhydroxide Derived from Metal–Organic Frameworks as Efficient Triphosphatase-like Nanozyme for Chromium(III) Ion Colorimetric Sensing

Yuhao Xiong, Linjing Su, Fanggui Ye and Shulin Zhao

ACS Appl. Bio Mater., 2021, 4, 6962
DOI: 10.1021/acsabm.1c00628

Enzymes metal-organic frameworks (MOFs) membrane: A review on design and applications

Pravin D. Patil, Anjali A. Halave, Aakanksha M. Ghadashi, Manishkumar S. Tiwari and Shamraja S. Nadar

International Journal of Biological Macromolecules, 2026, 338, 149631
DOI: 10.1016/j.ijbiomac.2025.149631

The Impacts of Ligand Removal and Metal Doping on the Peroxidase-like Activity of Au25(SR)18 Clusters

Zhou Huang, Qisheng Yan and Qing Tang

ACS Appl. Mater. Interfaces, 2025, 17, 42020
DOI: 10.1021/acsami.5c09608

One Probe, Two Readouts: A Fluorescent Nanozyme Facilitates Cascade Catalysis and On-Demand Bimodal Detection of Hepatic ALT and AST

Bo Wang, Linjie Wang, Xinyu Chen, Zheng Tang, Jinjin Liu, Shuangquan Liu, Xi Chen, Hao Liang and Xiangheng Niu

Anal. Chem., 2026, 98, 7832
DOI: 10.1021/acs.analchem.6c00083

Bifunctional oxidase-peroxidase mimicking Fe–Ce MOF on paper-based analytical devices to intensify luminol chemiluminescence: Application for measuring different sugars with a smartphone readout

Javad Hassanzadeh, Haider A.J. Al Lawati and Nafiseh Bagheri

Talanta, 2024, 276, 126219
DOI: 10.1016/j.talanta.2024.126219

Recent Progress and Prospect of Metal–Organic Framework-Based Nanozymes in Biomedical Application

Anupriya Baranwal, Shakil Polash, Vijay Aralappanavar, Bijay Behera, Vipul Bansal and Ravi Shukla

Nanomaterials, 2024, 14, 244
DOI: 10.3390/nano14030244

Metal-organic frameworks-based nanozyme sensor array for the discrimination of biogenic amines and detection of histamine

Jiahui Zou, Guancheng Zhu, Xueer Lin, Lanling Chu, Huimin Zhong, Cong Jiang and Yanyan Huang

Talanta, 2025, 284, 127244
DOI: 10.1016/j.talanta.2024.127244

Visible light-responsive vanadium-based metal–organic framework supported pepsin with high oxidase mimic activity for food spoilage monitoring

Amir Hossein Sharifnezhad, Kheibar Dashtian, Rouholah Zare-Dorabei and Mohammad Mahdavi

Microchim Acta, 2022, 189
DOI: 10.1007/s00604-022-05554-5

Anchoring atomically distributed Mn with N, F Co-doped ultrathin carbon matrixes as multifunctional nanozymes to boost electrochemical sensing performance

Xiaoqing Ma, Huali Zheng, Libin Fang, Hao Zhou, Wenbing Shi and Wenxi Zhao

Sensors and Actuators B: Chemical, 2025, 426, 137075
DOI: 10.1016/j.snb.2024.137075

Construction of electrocatalyst based on in-situ growth silver nanoparticles into hollow porous carbon spheres for hydrogen peroxide detection

Xiaoqing Ma, Kang Lu, Kang-lai Tang and Wenxi Zhao

Microchemical Journal, 2021, 170, 106713
DOI: 10.1016/j.microc.2021.106713

Nanozyme-integrated alcogel colorimetric sensor for rapid and on-site detection of tert-butyl hydroquinone

Shuai Liu, Hao Qu, Yu Mao, Lili Yao, Ling Yan, Baolei Dong and Lei Zheng

Journal of Hazardous Materials, 2024, 469, 133962
DOI: 10.1016/j.jhazmat.2024.133962

Nanozymes expanding the boundaries of biocatalysis

Ruofei Zhang, Xiyun Yan, Lizeng Gao and Kelong Fan

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-62063-8

The Brønsted-Lewis Acid Sites in Metal–Organic Framework Biomimetic Nanozyme for Cooperatively Enhancing the Hydrolysis of Lactose

Chenshu Yi, Keyu Xing, Keyu Xu, Li Yao, Pei Jia, Hao Wu, Li Wen, Yunhui Cheng and Zhou Xu

Catal Lett, 2024, 154, 5124
DOI: 10.1007/s10562-024-04699-7

Metal–Organic Framework‐Based Nanomaterials for Regulation of the Osteogenic Microenvironment

Wenzhuo Zheng, Zihan Meng, Zhou Zhu, Xu Wang, Xiangrui Xu, Yaowen Zhang, Yankun Luo, Yanhua Liu and Xibo Pei

Small, 2024, 20
DOI: 10.1002/smll.202310622

Quaternized chitosan enhances laccase-mimicking catalytic activity and stability of copper-based metal-organic framework for sensitive colorimetric detection of quercetin in food

Jiali Chen, Siyu Wu, Tingyue Yang, Jinlong Wang, Wangni Meng, Yue Tang, Pengcheng Yan and Yuangen Wu

International Journal of Biological Macromolecules, 2026, 369, 152658
DOI: 10.1016/j.ijbiomac.2026.152658

Aptamer functionalized nanomaterials for biomedical applications: Recent advances and new horizons

Mansour Mahmoudpour, Shichao Ding, Zhaoyuan Lyu, Ghasem Ebrahimi, Dan Du, Jafar Ezzati Nazhad Dolatabadi, Mohammadali Torbati and Yuehe Lin

Nano Today, 2021, 39, 101177
DOI: 10.1016/j.nantod.2021.101177

Biocatalytic Metal‐Organic Frameworks: Promising Materials for Biosensing

Wei Huang, Siming Huang, Guosheng Chen and Gangfeng Ouyang

ChemBioChem, 2022, 23
DOI: 10.1002/cbic.202100567

Computational Design and Experimental Validation of Enzyme Mimicking Cu-Based Metal–Organic Frameworks for the Reduction of CO2 into C2 Products: C–C Coupling Promoted by Ligand Modulation and the Optimal Cu–Cu Distance

Xin Mao, Wanbing Gong, Yang Fu, Jiayi Li, Xinyu Wang, Anthony P. O’Mullane, Yujie Xiong and Aijun Du

J. Am. Chem. Soc., 2023, 145, 21442
DOI: 10.1021/jacs.3c07108

CRISPR/Cas12a and Au@UiO-66 nanozyme synergistic dual amplification-based electrochemical biosensor for ultrasensitive ctDNA detection

Mingzhu Yang, Dujuan Li, Ao Wang, Yifan Zhang, Jiale Ouyang, Xinyi Wang, Liang Hong, Dingyi Tong, Minghua Wang, Jianhan Lin, Qiong Luo and Gaofeng Wang

Bioelectrochemistry, 2026, 171, 109300
DOI: 10.1016/j.bioelechem.2026.109300

One-step facile synthesis of polyphenol-assisted gold-platinum core-shell nanozymes for multi-enzyme mimicry in diabetic wound repair

Hafez Jafari, Lizhao Yan, Elham Dehghanpisheh, Pejman Ghaffari-bohlouli, Erika Hendrickx, Louise Conrard, Gian-Marco Rignanese, Lei Nie, Armin Shavandi and Peter Dubruel

Chemical Engineering Journal, 2026, 530, 173306
DOI: 10.1016/j.cej.2026.173306

Integration of multienzyme co-immobilization and biomimetic catalysis in magnetic metal–organic framework nanoflowers for α-amylase detection in fermentation samples

Liangqiang Chen, Mengdi Hao, Wanqiu Huang, Shaoning Yu, Hao Shen, Fan Yang, Li Wang and Huabin Tu

Food Chemistry, 2024, 446, 138773
DOI: 10.1016/j.foodchem.2024.138773

Efficient 2D MOFs nanozyme combining with magnetic SERS substrate for ultrasensitive detection of Hg2+

Runzi Zhang, Jia Yang, Yongguo Cao, Qianyan Zhang, Chenfeng Xie, Wanyi Xiong, Xiaojun Luo and Yi He

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 312, 124062
DOI: 10.1016/j.saa.2024.124062

Thiolated Ligand-Functionalized MoS2 Nanosheets for Peroxidase-like Activities

Sk Rajab Ali and Mrinmoy De

ACS Appl. Nano Mater., 2021, 4, 12682
DOI: 10.1021/acsanm.1c03242

A Cu-based metal-organic framework with two types of connecting nodes as catalyst for oxygen activation

Zhen Wang, Jun-Yu Li, Tao Huang, Huai-Ming Li and Teng Zhang

Chinese Chemical Letters, 2023, 34, 107635
DOI: 10.1016/j.cclet.2022.06.058

Cu-Based Metal–Organic Framework Nanoparticles for Sensing Cr(VI) Ions

Wei Shi, Mengqi He, Weitao Li, Xing Wei, Brian Bui, Mingli Chen and Wei Chen

ACS Appl. Nano Mater., 2021, 4, 802
DOI: 10.1021/acsanm.0c03118

Colorimetric Immunoassays with Boronic Acid-Decorated, Peroxidase-like Metal-Organic Frameworks as the Carriers of Antibodies and Enzymes

Ting Sun, Xinyao Yi, Lin Liu and Feng Zhao

Molecules, 2024, 29, 3000
DOI: 10.3390/molecules29133000

Metal-Organic frameworks for optical sensor arrays

Xin Zhang, Yuanjing Cui and Guodong Qian

Progress in Materials Science, 2025, 154, 101507
DOI: 10.1016/j.pmatsci.2025.101507

Metal–organic framework-engineered enzyme/nanozyme composites: Preparation, functionality, and sensing mechanisms

Yujie Li, Huining Chai, Zhishuang Yuan, Chaonan Huang, Shasha Wang, Yingjie Sun, Xueji Zhang and Guangyao Zhang

Chemical Engineering Journal, 2024, 496, 153884
DOI: 10.1016/j.cej.2024.153884

Catalytic synthesis of vitamin E acetate using metal organic framework material ZIF-8

Mingzhe Li, Yuyang Zhou, Hua Zhou and Dingqiang Lu

Journal of Coordination Chemistry, 2025, 78, 676
DOI: 10.1080/00958972.2025.2458650

Construction of Zn-heptapeptide bionanozymes with intrinsic hydrolase-like activity for degradation of di(2-ethylhexyl) phthalate

Shan Liang, Xiao-Ling Wu, Min-Hua Zong and Wen-Yong Lou

Journal of Colloid and Interface Science, 2022, 622, 860
DOI: 10.1016/j.jcis.2022.04.122

A High Selectively and Sensitively Fluorescent Europium Metal-Organic Framework Sensor for Detecting Nitro Aromatic Compounds in Aqueous Media

Jinsong Hu, Jing Zhang, Wenwen Sheng, Chen Sun, Tianci He, Yulong Zhang and Hong Chen

SSRN Journal, 2021
DOI: 10.2139/ssrn.3985834

Nanozymes with Multiple Activities: Prospects in Analytical Sensing

Xiangheng Niu, Bangxiang Liu, Panwang Hu, Hengjia Zhu and Mengzhu Wang

Biosensors, 2022, 12, 251
DOI: 10.3390/bios12040251

Amorphous iron-catecholates featuring efficient peroxidase-like activity for quick colorimetric detection of tannic acid

Cunhui Wu, Zhiyang Qin, Yixin Liu, Xinguang Qin, Gang Liu, Xinlin Wei and Haizhi Zhang

LWT, 2024, 197, 115896
DOI: 10.1016/j.lwt.2024.115896

Realizing selective detection with nanozymes: Strategies and trends

Xin Li, Hengjia Zhu, Peng Liu, Mengzhu Wang, Jianming Pan, Fengxian Qiu, Liang Ni and Xiangheng Niu

TrAC Trends in Analytical Chemistry, 2021, 143, 116379
DOI: 10.1016/j.trac.2021.116379

Antioxidant Nanozymes: Mechanisms, Activity Manipulation, and Applications

Nguyen Thi My Thao, Hoang Dang Khoa Do, Nguyen Nhat Nam, Nguyen Khoi Song Tran, Thach Thi Dan and Kieu The Loan Trinh

Micromachines, 2023, 14, 1017
DOI: 10.3390/mi14051017

Electrochemical dopamine sensor based on bi-metallic Co/Zn porphyrin metal–organic framework

Junping Ma, Wushuang Bai, Xiaoli Liu and Jianbin Zheng

Microchim Acta, 2022, 189
DOI: 10.1007/s00604-021-05122-3

Nanocatalysis meets microfluidics: A powerful platform for sensitive bioanalysis

Yanfeng Gao, Yanping Wang, Yuzhen Wang, Pascale Magaud, Yuta Liu, Fei Zeng, Jingjing Yang, Lucien Baldas and Yujun Song

TrAC Trends in Analytical Chemistry, 2023, 158, 116887
DOI: 10.1016/j.trac.2022.116887

Bimetallic Metal–Organic Framework Fe/Co-MIL-88(NH2) Exhibiting High Peroxidase-like Activity and Its Application in Detection of Extracellular Vesicles

Qiaoshi Jiang, Yuchen Xiao, Anh N. Hong, Ziting Gao, Yuyang Shen, Qingsong Fan, Pingyun Feng and Wenwan Zhong

ACS Appl. Mater. Interfaces, 2022, 14, 41800
DOI: 10.1021/acsami.2c12115

High-sensitive glucose sensor based on tilted fiber Bragg gratings

Feng Xu, Ruichen Dai, Yutao Guo, Mengying Hu, Xin Wang and Yunhe Zhao

Optics Communications, 2024, 569, 130861
DOI: 10.1016/j.optcom.2024.130861

Biosensors with Metal Ion–Phosphate Chelation Interaction for Molecular Recognition

Xiaohua Ma, Yuanqiang Hao, Xiaoxiao Dong and Ning Xia

Molecules, 2023, 28, 4394
DOI: 10.3390/molecules28114394

Recent advances in MOF-based nanozymes: Synthesis, activities, and bioapplications

Yan Zhang, Chengfeng Zhang, Wanlong Qian, Fang Lei, Zhongping Chen, Xiaomei Wu, Youhui Lin and Faming Wang

Biosensors and Bioelectronics, 2024, 263, 116593
DOI: 10.1016/j.bios.2024.116593

Protein‐Mimicking Nanoparticles in Biosystems

Xiaoyuan Ji, Qian Li, Haiyun Song and Chunhai Fan

Advanced Materials, 2022, 34
DOI: 10.1002/adma.202201562

Recent advances in metal-organic framework-based nanozymes and their enabled optical biosensors for food safety analysis

Huirong Hou, Li Wang, Yibo Gao, Jianfeng Ping and Fengnian Zhao

TrAC Trends in Analytical Chemistry, 2024, 173, 117602
DOI: 10.1016/j.trac.2024.117602

Dual-functionality in one MOF: Tailored AuNC@MOF hybrids with synergistic oxidase-mimetic activity and fluorescence amplification for multi-modal tannic acid sensing

Shun Wang, Beibei Han, Guoming Sun, Mengke Wang and Qing Li

Sensors and Actuators B: Chemical, 2026, 448, 138935
DOI: 10.1016/j.snb.2025.138935

Recent progress in advanced materials for electrochemical determination of phenolic contaminants

Chuantao Gu, Xinze Su, Bing Liu, Chunying Zheng, Shasha Wang, Yong Tian, Jiping Ma and Lingxia Wu

Microchemical Journal, 2023, 195, 109513
DOI: 10.1016/j.microc.2023.109513

The Exploration of Nanozymes for Biosensing of Pathological States Tailored to Clinical Theranostics

Abdul Sayeed Khan, Sudhir Kumar Sahu, Santosh Kumar Dash, Tankadhar Mishra, Amiya Ranjan Padhan, Damodar Padhan, Sribatsa Lanchhana Dash and Manoj Kumar Sarangi

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202401326

Rapid on-site colorimetric detection of arsenic(V) by NH2-MIL-88(Fe) nanozymes-based ultraviolet-visible spectroscopic and smartphone-assisted sensing platforms

Kewei Ren, Yuanfang Li and Qingqing Liu

Analytica Chimica Acta, 2025, 1336, 343523
DOI: 10.1016/j.aca.2024.343523

Excellent Laccase Mimic Activity of Cu-Melamine and Its Applications in the Degradation of Congo Red

Siyuan Chai, Enze Huang, Jiashuai Zeng, Yangyang Shi, Jiashuo Zhang and Xia Zhang

Appl Biochem Biotechnol, 2025, 197, 3332
DOI: 10.1007/s12010-024-05172-2

Oxidase-like Nanozyme Activity of Manganese Metal–Organic Framework Nanosheets for Colorimetric and Fluorescence Sensing of l-Cysteine

Ajit Kumar Singh, Kriti Bijalwan, Neha Kaushal, Anu Kumari, Avishek Saha and Arindam Indra

ACS Appl. Nano Mater., 2023, 6, 8036
DOI: 10.1021/acsanm.3c01404

PTC-NH2@MOFs-AuNCs: A novel bifunctional signal probe for ratiometric electrochemiluminescence/colorimetry dual-mode aptasensing of lead ion

Libo Li, Panao Jiang, Meiyang Zhen, Xiaohong Liu, Lijun Luo, Wenzhen Lv, Lin Luo and Tianyan You

Chemical Engineering Journal, 2024, 499, 156185
DOI: 10.1016/j.cej.2024.156185

Synergistic co-catalytic nanozyme system for highly efficient one-pot colorimetric sensing at neutral pH: Combining molybdenum trioxide and Fe(III)-Modified covalent triazine framework

Jingyan Xu, Hanying Tan, Xionghui Ma, Linjing Su, Zhi Zhang and Yuhao Xiong

Analytical Biochemistry, 2024, 685, 115391
DOI: 10.1016/j.ab.2023.115391

Advancing stroke therapy: the potential of MOF-based nanozymes in biomedical applications

Meirong Chen, Yang Qin, Yongmei Peng, Ruyu Mai, Huanyao Teng, Zhongquan Qi and Jingxin Mo

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1363227

Synthesis of Mn-ZIF-67 for efficient degradation of tetracycline

Wenzhong Zhu, Xueting Zhu, Weijian Shen, Nan An and Lina Wu

J Mater Cycles Waste Manag, 2024, 26, 2910
DOI: 10.1007/s10163-024-02015-4

Nanomaterial-enhanced 3D-printed sensor platform for simultaneous detection of atrazine and acetochlor

Xiaofan Ruan, Yijia Wang, Eunice Y. Kwon, Limin Wang, Nan Cheng, Xiangheng Niu, Shichao Ding, Bernard J. Van Wie, Yuehe Lin and Dan Du

Biosensors and Bioelectronics, 2021, 184, 113238
DOI: 10.1016/j.bios.2021.113238

Oxidase-like nanozymes-driven colorimetric, fluorescence and electrochemiluminescence assays for pesticide residues

Sha Liu, Chao Nie, Fengjiao He, Guojian Wu, Heng Wang, Si Li, Chenxing Du, Zhi Zheng, Jieshun Cheng, Yizhong Shen and Jie Cheng

Trends in Food Science & Technology, 2024, 150, 104597
DOI: 10.1016/j.tifs.2024.104597

Metal-organic framework (MOF)-derived flower-like Ni-MOF@NiV-layered double hydroxides as peroxidase mimetics for colorimetric detection of hydroquinone

Yin He, Min Feng, Xiaodan Zhang and Yuming Huang

Analytica Chimica Acta, 2023, 1283, 341959
DOI: 10.1016/j.aca.2023.341959

Integrating peroxidase-mimicking NH2-MIL-101(Fe) with molecular imprinting for high-performance ratiometric fluorescence sensing of domoic acid

Linjie Wang, Lejuan Wen, Shujun Zheng, Feifei Tao, Jie Chao, Fei Wang and Caolong Li

Sensors and Actuators B: Chemical, 2022, 361, 131688
DOI: 10.1016/j.snb.2022.131688

Ratiometric fluorescence assay for sulfide ions with fluorescent MOF-based nanozyme

Nianlei Zhu, Tinghui Deng, Ya-Nan Zuo, Jing Sun, Huwei Liu, Xian-En Zhao and Shuyun Zhu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 295, 122620
DOI: 10.1016/j.saa.2023.122620

Inorganic Fe-O and Fe-S oxidoreductases: paradigms for prebiotic chemistry and the evolution of enzymatic activity in biology

Xiao-Lan Huang, Jeffrey R. Harmer, Gerhard Schenk and Gordon Southam

Front. Chem., 2024, 12
DOI: 10.3389/fchem.2024.1349020

Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review

Liu Tong, Lina Wu, Enben Su, Yan Li and Ning Gu

Chemosensors, 2023, 11, 233
DOI: 10.3390/chemosensors11040233

MnO2 Decorated Metal‐Organic Framework‐Based Hydrogel Relieving Tumor Hypoxia for Enhanced Photodynamic Therapy

Yifan Li, Jian Wang, Hanrong Li, Miantong Guo, Xiaoyan Sun, Chaoyong Liu and Changyuan Yu

Macromol. Rapid Commun., 2023, 44
DOI: 10.1002/marc.202300268

Engineering metal-organic frameworks-based nanozymes for enhanced biomimetic catalytic sensing

Zhong Wei Jiang, Xue Gong, Yi Wang, Yuan Fang Li and Cheng Zhi Huang

TrAC Trends in Analytical Chemistry, 2024, 178, 117862
DOI: 10.1016/j.trac.2024.117862

Recent advances in biomedical applications of 2D nanomaterials with peroxidase-like properties

Zhaoyuan Lyu, Shichao Ding, Dan Du, Kaiyan Qiu, Jin Liu, Kanako Hayashi, Xiao Zhang and Yuehe Lin

Advanced Drug Delivery Reviews, 2022, 185, 114269
DOI: 10.1016/j.addr.2022.114269

3D-Printed Flexible Microfluidic Health Monitor for In Situ Sweat Analysis and Biomarker Detection

Chuchu Chen, Yonghao Fu, Sonja S. Sparks, Zhaoyuan Lyu, Arijit Pradhan, Shichao Ding, Narasimha Boddeti, Yun Liu, Yuehe Lin, Dan Du and Kaiyan Qiu

ACS Sens., 2024, 9, 3212
DOI: 10.1021/acssensors.4c00528

Two-dimensional hybrid nanozymes for biomedical applications

Yawen Yang, Xingyu Zhou, Dawei Shang, Maben Xu, Liwen Yu, Peiyao Han, Xiaowei Huang, Tao Li and Shaohua Wu

emergent mater., 2026, 9
DOI: 10.1007/s42247-026-01319-5

Weak Coordination Bond of Chloromethane: A Unique Way to Activate Metal Node Within an Unstable Metal–Organic Framework DUT‐34

Jinhee Bae, Chang Yeon Lee and Nak Cheon Jeong

Bulletin Korean Chem Soc, 2021, 42, 658
DOI: 10.1002/bkcs.12268

Multivalent Ce-MOFs as biomimetic laccase nanozyme for environmental remediation

Shan Liang, Xiao-Ling Wu, Jun Xiong, Xin Yuan, Shu-Li Liu, Min-Hua Zong and Wen-Yong Lou

Chemical Engineering Journal, 2022, 450, 138220
DOI: 10.1016/j.cej.2022.138220

Engineering bimetallic nanozyme structures for enhanced catalytic activity and multifunctional applications

Zhuo Wen, Yilin Zhao, Heyuan Zhao, Yilang Chen, Gang Xiao and Haijia Su

Discov Catal, 2026, 3
DOI: 10.1007/s44344-025-00030-7

Aptamer modified CeCo MOF hybrid catalysts with multiple enzymatic activities for enhanced catalytic therapy of infected wounds

Yingxin Zhou, Wanqing Zou, Yulu Zhang, Haolan Fang, Fayin Mo, Duanping Sun, Xuanxuan Zhang and Tianhui You

International Journal of Biological Macromolecules, 2025, 285, 138215
DOI: 10.1016/j.ijbiomac.2024.138215

Metal-organic framework as a mimetic enzyme with excellent adaptability for sensitive chemiluminescence detection of glutathione in cell lysate

Hongjing Yang, Jiao Liu, Lina Wang, Lifeng Ma, Fei Nie and Guoping Yang

Talanta, 2022, 238, 123041
DOI: 10.1016/j.talanta.2021.123041

Engineering Colloidal Nanozymes for Cancer Diagnosis and Therapy: From Surface Chemistry to Catalytic Mechanisms and Precision Medicine

Mohammed Ali Dheyab, Azlan Abdul Aziz, Wesam Abdullah, Saleh T. Alanezi, Wasan Hussein Kasasbeh, Firas Fohely, Pegah Moradi Khaniabadi, Mahmood S. Jameel, Nazila Oladzadabbasabadi and Mehran Ghasemlou

ACS Appl. Bio Mater., 2025, 8, 4514
DOI: 10.1021/acsabm.5c00495

Electrochemical Sensor for Detection of Hydrogen Peroxide Based on Cu-doped ZIF-8 material modified with Chitosan and Cytochrome C

Hui Yao, Wan-ting Zhang, Ting-yu Yan, Xiao-qin Li and Xiao-feng Wang

International Journal of Electrochemical Science, 2022, 17, 220654
DOI: 10.20964/2022.06.68

Explaining chemical clues of metal organic framework-nanozyme nano-/micro-motors in targeted treatment of cancers: benchmarks and challenges

Mojtaba Falahati, Majid Sharifi and Timo L. M. Ten Hagen

J Nanobiotechnol, 2022, 20
DOI: 10.1186/s12951-022-01375-z

When nanozymes meet deoxyribonucleic acid: Understanding their interactions and biomedical diagnosis applications

Hao Liang, Xinyu Chen, Zhijian Bu, Qinqin Bai, Jinjin Liu, Qingzhen Tian, Zheng Tang, Shu Li, Qiaoqiao Diao and Xiangheng Niu

Interdisciplinary Medicine, 2024, 2
DOI: 10.1002/INMD.20230057

Efficient Biocatalytic System for Biosensing by Combining Metal–Organic Framework (MOF)-Based Nanozymes and G-Quadruplex (G4)-DNAzymes

Xuanxiang Mao, Fangni He, Dehui Qiu, Shijiong Wei, Rengan Luo, Yun Chen, Xiaobo Zhang, Jianping Lei, David Monchaud, Jean-Louis Mergny, Huangxian Ju and Jun Zhou

Anal. Chem., 2022, 94, 7295
DOI: 10.1021/acs.analchem.2c00600

A novel laccase-like Cu-MOF for colorimetric differentiation and detection of phenolic compounds

Ziyi Gao, Jianping Guan, Meng Wang, Shenghong Liu, Kecen Chen, Qi Liu and Xiaoqing Chen

Talanta, 2024, 272, 125840
DOI: 10.1016/j.talanta.2024.125840

Metal–organic frameworks as highly effective platforms for enzyme immobilization–current developments and future perspectives

Justyna Rogacka and Karolina Labus

Braz. J. Chem. Eng., 2024, 42, 1273
DOI: 10.1007/s43153-024-00513-4

Fabrication of novel copper MOF nanoparticles for nanozymatic detection of mercury ions

Kirandeep, Jaspreet Kaur, Indu Sharma, Ennio Zangrando, Kaushik Pal, Surinder Kumar Mehta and Ramesh Kataria

Journal of Materials Research and Technology, 2023, 22, 278
DOI: 10.1016/j.jmrt.2022.10.167

Cascade electrochemiluminescence-based integrated graphitic carbon nitride-encapsulated metal-organic framework nanozyme for prostate-specific antigen biosensing

Seyyed Mehdi Khoshfetrat, Pegah Hashemi, Abbas Afkhami, Ali Hajian and Hasan Bagheri

Sensors and Actuators B: Chemical, 2021, 348, 130658
DOI: 10.1016/j.snb.2021.130658

Fusing bacteriophage specificity with MOF nanozyme catalysis to construct an AI-enhanced platform for simultaneous pathogen detection and eradication

Zixin Ming, Menghan Zhou, Xi Liu, Peng Guan, Sam R. Nugen, Harish Menghwar, Chenxi Huang and Xiaohong Wang

Chemical Engineering Journal, 2025, 525, 170578
DOI: 10.1016/j.cej.2025.170578

Recent Advances in Metal–Organic Framework-Based Nanozymes for Intelligent Microbial Biosensing: A Comprehensive Review of Biomedical and Environmental Applications

Alemayehu Kidanemariam and Sungbo Cho

Biosensors, 2025, 15, 437
DOI: 10.3390/bios15070437

Emerging Nanomaterials as Versatile Nanozymes: A New Dimension in Biomedical Research

Evin Jacob, Denno Mathew, Libina Benny and Anitha Varghese

Top Curr Chem (Z), 2024, 382
DOI: 10.1007/s41061-024-00473-w

A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme

Ying Sun, Tianran Lin, Cuihong Zeng, Gaoyan Jiang, Xuanhan Zhang, Fanggui Ye and Shulin Zhao

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-04808-y

Biomimetic electrochemical sensors: New horizons and challenges in biosensing applications

Pedro V.V. Romanholo, Claudia A. Razzino, Paulo A. Raymundo-Pereira, Thiago M. Prado, Sergio A.S. Machado and Livia F. Sgobbi

Biosensors and Bioelectronics, 2021, 185, 113242
DOI: 10.1016/j.bios.2021.113242

Biocompatible Cerium Carbonate-Based Nanozymes for Oxidase Activity, Sensing, Computed Tomography Contrast, and Delivery of Small Molecules

Suresh Thangudu, Chun Jiat Lee and Chia-Hao Su

ACS Appl. Nano Mater., 2023, 6, 12922
DOI: 10.1021/acsanm.3c01652

Smartphone-assisted colorimetric detection of glutathione in food and pharmaceutical samples using MIL-88A(Fe)

Nilmani Kumar, Harpreet Singh, Akash Deep, Madhu Khatri and Neha Bhardwaj

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 326, 125297
DOI: 10.1016/j.saa.2024.125297

Unveiling the role of inorganic nanoparticles in Earth’s biochemical evolution through electron transfer dynamics

Xiao-Lan Huang

iScience, 2024, 27, 109555
DOI: 10.1016/j.isci.2024.109555

Biomimetic mineralization materials for heterogeneous chemo-enzymatic cascade catalytic systems: Theaters and players

Mengyu Li, Fenfen You, Keke Zhang, Jingliang Xu, Wei Zhuang, Jun Ge and Zhenfu Wang

Chemical Engineering Journal, 2025, 509, 161282
DOI: 10.1016/j.cej.2025.161282

Host–Guest Interactions Induced Enhancement in Oxidase-Like Activity of a Benzothiadiazole Dye Inside an Aqueous Pd8L4 Barrel

Debsena Chakraborty, Navjot Kaur, Jagabandhu Sahoo, Neal Hickey, Mrinmoy De and Partha Sarathi Mukherjee

J. Am. Chem. Soc., 2024, 146, 24901
DOI: 10.1021/jacs.4c05899

Surfactant-based metal-organic frameworks (MOFs) in the preparation of an active biocatalysis

Elif Ozyilmaz, Mustafa Baris Kocer, Ozge Caglar, Ayse Yildirim and Mustafa Yilmaz

Journal of Biotechnology, 2023, 371-372, 10
DOI: 10.1016/j.jbiotec.2023.06.003

Carbon Quantum Dots-Based Nanozyme from Coffee Induces Cancer Cell Ferroptosis to Activate Antitumor Immunity

Lu Yao, Mei-Mei Zhao, Qian-Wei Luo, Yi-Chi Zhang, Ting-Ting Liu, Zhuo Yang, Min Liao, Pengfei Tu and Ke-Wu Zeng

ACS Nano, 2022, 16, 9228
DOI: 10.1021/acsnano.2c01619

When nanozymes meet enzyme: Unlocking the dual-activity potential of integrated biocomposites

Pravin D. Patil, Aparna Karvekar, Sakshi Salokhe, Manishkumar S. Tiwari and Shamraja S. Nadar

International Journal of Biological Macromolecules, 2024, 271, 132357
DOI: 10.1016/j.ijbiomac.2024.132357

The Dual-Faceted Role of Metal-Based Nanomaterials in Hepatic Fibrosis Therapy

Yinqing Mao, Yankai Gong and Xue Bai

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S574077

Nanozymes on paper: Transforming microfluidic devices for portable biosensing

Junjie Zhao, Ergui Luo, Wenjuan Wang, Zhi Du and Di Huang

Talanta, 2026, 305, 129646
DOI: 10.1016/j.talanta.2026.129646

Recent Advances in Metal–Organic Framework-Based Nanozymes for Enhanced Biosensing Applications

Jianping Wang, Xiaoying Zhou, Zhonghao Dai, Lu Xu, Siyu Nie, Dongjie Yang, Yi Yang, Liyuan Wang, Jiayun Yao and Zihong Ye

Biosensors, 2026, 16, 197
DOI: 10.3390/bios16040197

The expanding horizon of aptamer-modified metal-organic framework for the biosensing of chronic kidney disease biomarkers

Monika Chhillar, Poornima Bhatt, Deepak Kukkar and Ki-Hyun Kim

Microchemical Journal, 2026, 225, 118121
DOI: 10.1016/j.microc.2026.118121

Multifunctional light-controllable nanozyme enabled bimodal fluorometric/colorimetric sensing of mercury ions at ambient pH

Panwang Hu, Yuhan Tang, Hengjia Zhu, Changkun Xia, Jinjin Liu, Bangxiang Liu and Xiangheng Niu

Biosensors and Bioelectronics, 2023, 238, 115602
DOI: 10.1016/j.bios.2023.115602

Research on the application of metal-organic framework (MOF)-based nanozymes in colorimetric and electrochemical detection of biomolecules

Xingxing Li, Li Fu, Fei Chen, Yanfei Lv, Shichao Zhao and Hassan Karimi-Maleh

Inorganic Chemistry Communications, 2025, 179, 114752
DOI: 10.1016/j.inoche.2025.114752

Ratiometric electrochemical immunoassay based on 2D Co/Fe MOF decorated with toluidine blue and Fc-labeled Schiff base for accurate assay of alpha-fetoprotein in clinical serum

He-Nan Sun, Miao Wang, Hong-Sheng Tan, Hui-Ping Liu, Mingjun Liu and Shan-Shan Li

Talanta, 2024, 273, 125876
DOI: 10.1016/j.talanta.2024.125876

Two dimensional iron metal-organic framework nanosheet with peroxidase-mimicking activity for colorimetric detection of hypoxanthine related to shrimp freshness

Hongyuan Wu, Zhuolan Xu, Danni Xiong, Xinguang Qin, Gang Liu and Haizhi Zhang

Talanta, 2023, 265, 124833
DOI: 10.1016/j.talanta.2023.124833

MoO3/MIL-125-NH2 with boosted peroxidase-like activity for electrochemical staphylococcus aureus sensing via specific recognition of bacteriophages

Yajun Gao, Suhui Xu, Ge Guo, Yajie Li, Wenyuan Zhou, Huaxiang Li and Zhenquan Yang

Biosensors and Bioelectronics, 2024, 252, 116134
DOI: 10.1016/j.bios.2024.116134

Magnetic nanocomposites as multifunctional carriers for enzymes immobilization: a review

Li Zaixing, Li Chao, Zhang Qinqin, Hong Chen, Zhang Wenjing, Xu Bingbing, Qin Xue, Li Guixia and Ning Zhifang

Chem. Pap., 2024, 78, 1353
DOI: 10.1007/s11696-023-03173-9

Multiple Enzyme-Mimicking CuMOF-Driven Self-Cascading Antioxidant Reaction for Synergistic Electrochemiluminescence Modulation in Ultrasensitive Biosensing

Huifang Zhang, Yuhang Zhang, Xuan Hu, Xiang Xu, Yanmin Yang, Xiaoming Ma, Yuexiang Li and Zhenyu Lin

Anal. Chem., 2024, 96, 16072
DOI: 10.1021/acs.analchem.4c03933

Quercetin-loaded zeolitic imidazolate framework-8 nanoparticles through borneol-embedded hyaluronic acid hydrogel for ischemic stroke treatment

Yawen Yu, Yuxuan Zou, Mingyan Yang, Dalei Li, Jiali Zhao, Yaping He, Xinxin Bai, Yami Wu, Fei Yao and Huaying Fan

International Journal of Biological Macromolecules, 2026, 340, 149821
DOI: 10.1016/j.ijbiomac.2025.149821

Design of MOF-based nanobiocatalyst with super-catalytic properties with iron mineralization approach

Elif Ozyilmaz, M. Sami Biltekin, Ozge Caglar and Mustafa Yilmaz

Materials Letters, 2021, 305, 130768
DOI: 10.1016/j.matlet.2021.130768

Bioinspired Popcorn‐Like Nitrogen‐Doped Nickel Sulphide as Superoxide Dismutase Mimicking Nanozyme Toward Selective Electrochemical Detection of Superoxide Anions

Vadakke Purakkal Sruthi and Sellappan Senthilkumar

Small, 2026, 22
DOI: 10.1002/smll.202513409

Single‐Atomic Site Catalyst with Heme Enzymes‐Like Active Sites for Electrochemical Sensing of Hydrogen Peroxide

Shichao Ding, Zhaoyuan Lyu, Lingzhe Fang, Tao Li, Wenlei Zhu, Suiqiong Li, Xin Li, Jin‐Cheng Li, Dan Du and Yuehe Lin

Small, 2021, 17
DOI: 10.1002/smll.202100664

Ni-MOF embedded with carbon nanomaterials/polypyrrole/riboflavin oxidase biomimetic recognition for direct and ultrasensitive electrochemical detection of prostate cancer biomarker

Ponnusamy Arul, Chinnathambi Nandhini, Sheng-Tung Huang, Chi-Hsien Huang and N.S.K. Gowthaman

Sensors and Actuators B: Chemical, 2025, 444, 138410
DOI: 10.1016/j.snb.2025.138410

Versatile POMOF-based materials: Synthesis, mechanism, topology and catalytic applications

Zhengxiang Sun, Rui Wang and Ivan V. Kozhevnikov

Coordination Chemistry Reviews, 2025, 524, 216304
DOI: 10.1016/j.ccr.2024.216304

Multifunctional metal-organic framework based nanozymes: From synthesis to fluorescent and colorimetric dual mode sensing in food safety

Bakhtawar Shafique, Zuyao Fu, Hao Wang, Jing Xie and Zhaoyang Ding

Food Control, 2025, 178, 111497
DOI: 10.1016/j.foodcont.2025.111497

MOFs and CRISPR: A powerful duo for biosensing nucleic acid and proteins

Snehlata Kujur, Sneha Kumari Binha and Dinesh Prasad

Microchemical Journal, 2025, 219, 116143
DOI: 10.1016/j.microc.2025.116143

Metal-organic frameworks for therapeutic gas delivery

Yingzhu Zhou, Tao Yang, Kang Liang and Rona Chandrawati

Advanced Drug Delivery Reviews, 2021, 171, 199
DOI: 10.1016/j.addr.2021.02.005

Bimetallic and multimetallic nanoparticles as nanozymes

Mariusz Pietrzak and Polina Ivanova

Sensors and Actuators B: Chemical, 2021, 336, 129736
DOI: 10.1016/j.snb.2021.129736

Selective Hydrolysis of Heterooligosaccharides by Poly(acrylate) Gel Catalysts

Susanne Striegler

ACS Catal., 2024, 14, 16723
DOI: 10.1021/acscatal.4c04697

A novel copper-based metal-organic framework as a peroxidase-mimicking enzyme and its glucose chemiluminescence sensing application

Hongjing Yang, Jiao Liu, Xuan Feng, Fei Nie and Guoping Yang

Anal Bioanal Chem, 2021, 413, 4407
DOI: 10.1007/s00216-021-03394-5

A Comprehensive Review of Multifunctional Nanozymes for Degradation and Detection of Organophosphorus Pesticides in the Environment

Jijia Liang, Zhongtian Dong, Ning Xu, Tao Chen, Jie Liang, Mingzhu Xia and Fenghe Wang

Toxics, 2024, 12, 926
DOI: 10.3390/toxics12120926

Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

Lu Yang, Shuming Dong, Shili Gai, Dan Yang, He Ding, Lili Feng, Guixin Yang, Ziaur Rehman and Piaoping Yang

Nano-Micro Lett., 2024, 16
DOI: 10.1007/s40820-023-01224-0

Pt Nanoparticles Anchored on NH2-MIL-101 with Efficient Peroxidase-Like Activity for Colorimetric Detection of Dopamine

Jing Li, Keying Xu, Yang Chen, Jie Zhao, Peiyao Du, Libing Zhang, Zhen Zhang and Xiaoquan Lu

Chemosensors, 2021, 9, 140
DOI: 10.3390/chemosensors9060140

Prospects of Exploring the Metal–Organic Framework for Combating Antimicrobial Resistance

Shakil Ahmed Polash, Tushar Khare, Vinay Kumar and Ravi Shukla

ACS Appl. Bio Mater., 2021, 4, 8060
DOI: 10.1021/acsabm.1c00832

Advances in applications of nanoenzymes in antibiotic detection

Xingchen Qiu, Cunxia Fan, Rui Bai, Ziyao Tang, Yu Gu and Changming Li

Chin. Sci. Bull., 2024, 69, 553
DOI: 10.1360/TB-2023-0605

Dual-Mode Lateral Flow Immunoassay Based on “Pompon Mum”-Like Fe3O4@MoS2@Pt Nanotags for Sensitive Detection of Viral Pathogens

Meimei Xu, Shuai Zhao, Chenglong Lin, Yanyan Li, Weida Zhang, Yusi Peng, Rui Xiao, Zhengren Huang and Yong Yang

ACS Appl. Mater. Interfaces, 2024, 16, 11172
DOI: 10.1021/acsami.3c15851

Engineering Two-Dimensional-Copper Phenolic Nanosheet from CuO Nanosphere for Enhanced Peroxidase Activity in Smartphone-Based Thiophanate-Methyl Detection via Analyte-Inhibition Mechanism

Arunjegan Amalraj, Ravikumar Ayyanu, Emmanuel Chigozie Aham, Dali Wei, Govindaraj Tamil Selvan, Zhen Zhang and Hongjun Zhao

Langmuir, 2025, 41, 6959
DOI: 10.1021/acs.langmuir.4c05271

A mitochondria-targeted nanomedicine for myocardial ischemia/reperfusion injury with synergistic antioxidant and anti-inflammatory properties

Congcong Li, Zhengfeng Zhang, Chao Luo, Wanqi Lan, Chen Liu, Wu Liu, Haiyan Xiang, Juesheng Yang, Yanhua Tang and Xiaolei Wang

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03810-3

Nanozyme based on bimetallic metal–organic frameworks and their applications: A review

Kawan F. Kayani

Microchemical Journal, 2025, 208, 112363
DOI: 10.1016/j.microc.2024.112363

High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in Colorimetric–SERS Dual-Mode Detection

Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang and Shijia Wu

Anal. Chem., 2025, 97, 19829
DOI: 10.1021/acs.analchem.5c03609

Single-Atomic Site Catalyst Enhanced Lateral Flow Immunoassay for Point-of-Care Detection of Herbicide

Zhaoyuan Lyu, Shichao Ding, Peter Tieu, Lingzhe Fang, Xin Li, Tao Li, Xiaoqing Pan, Mark H. Engelhard, Xiaofan Ruan, Dan Du, Suiqiong Li and Yuehe Lin

Research, 2022, 2022
DOI: 10.34133/2022/9823290

Atomically Fe‐anchored MOF‐on‐MOF nanozyme with differential signal amplification for ultrasensitive cathodic electrochemiluminescence immunoassay

Chuanping Li, Tianxiang Hang and Yongdong Jin

Exploration, 2023, 3
DOI: 10.1002/EXP.20220151

The color code: MOFs unlocking new horizons in chemical sensing

Paulina Miklaszewska and Ewa Wagner-Wysiecka

Applied Materials Today, 2025, 47, 102966
DOI: 10.1016/j.apmt.2025.102966

Nanozyme‐Enabled Biomedical Diagnosis: Advances, Trends, and Challenges

Qingzhen Tian, Shu Li, Zheng Tang, Ziyu Zhang, Dan Du, Xiao Zhang, Xiangheng Niu and Yuehe Lin

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202401630

Recent development of nanozymes for dual and multi-mode biosensing applications in food safety and environmental monitoring: A review

Sofiene Mansouri and Ahmed AlOmari

Journal of Environmental Chemical Engineering, 2025, 13, 116832
DOI: 10.1016/j.jece.2025.116832

Understanding the potential-induced activation of a cobalt MOF electrocatalyst for the oxygen evolution reaction

Silvia Gutiérrez-Tarriño, Arismendy Portorreal-Bottier, Susana Trasobares, Juan José Calvente, Jose J. Calvino, José Luis Olloqui-Sariego and Pascual Oña-Burgos

Applied Surface Science, 2023, 623, 157001
DOI: 10.1016/j.apsusc.2023.157001

Cluster Nuclearity Determines Substrate Adsorption/Desorption Dynamics and Peptidase Activity of UiO-66 Nanozymes

Siene Swinnen, Bettina Baumgartner, Bartosz Trzaskowski, Angelo Mullaliu, Bert M. Weckhuysen, Francisco de Azambuja and Tatjana N. Parac-Vogt

Chem. Mater., 2025, 37, 2772
DOI: 10.1021/acs.chemmater.4c03365

Amorphous copper(II)-cyanoimidazole frameworks as peroxidase mimics for hydrogen sulfide assay

Zijun Ding, Xiaoying Gao, Yanmei Yang, Hua Wei, Shenghong Yang and Jian Liu

Journal of Colloid and Interface Science, 2023, 652, 1889
DOI: 10.1016/j.jcis.2023.09.014

Fluorescent/colorimetric probe for the detection of Cr(Ⅵ) based on MIL-101(Fe)–NH2 with peroxidase-like activity

Shengyuan Zhang, Haiyan Li, Dezhi Yang and Yaling Yang

Talanta, 2024, 280, 126785
DOI: 10.1016/j.talanta.2024.126785

Advances in Nanozymes as a Paradigm for Viral Diagnostics and Therapy

Garima Sharma, Srijan Chatterjee, Chiranjib Chakraborty and Jin-Chul Kim

Pharmacological Reviews, 2023, 75, 739
DOI: 10.1124/pharmrev.122.000719

Facile molecular imprinting on magnetic nanozyme surface for highly selective colorimetric detection of tetracycline

Bangxiang Liu, Hengjia Zhu, Rulin Feng, Mengzhu Wang, Panwang Hu, Jianming Pan and Xiangheng Niu

Sensors and Actuators B: Chemical, 2022, 370, 132451
DOI: 10.1016/j.snb.2022.132451

Chemiluminescence “Add-and-Measure” Sensing Paper Based on the Prussian Blue/Metal–Organic Framework MIL-101 Nanozyme for Rapid Hydrogen Peroxide Detection

Héctor Martínez-Pérez-Cejuela, Maria Maddalena Calabretta and Elisa Michelini

Anal. Chem., 2024, 96, 16561
DOI: 10.1021/acs.analchem.4c02340

Multifunctional nanozymatic biosensors: Awareness, regulation and pathogenic bacteria detection

Yiyao Zhang, Fang Mi, Yajun Zhao, Pengfei Geng, Shan Zhang, Han Song, Guotong Chen, Bo Yan and Ming Guan

Talanta, 2025, 292, 127957
DOI: 10.1016/j.talanta.2025.127957

Highly Efficient Sensing of Hydrogen Peroxide Based on Atomically Dispersed Iron- and Nitrogen-Doped Carbon

Jingchao Chen, Jie Yang, Ruimin Ding, Shanshan Liu, Lifang Chen, Wenwen Shi and Xi Yin

J. Electrochem. Soc., 2023, 170, 027503
DOI: 10.1149/1945-7111/acb850

Engineered Prussian Blue‐Curcumin Nanozyme with RONS Scavenging Properties for Augmented Reversible Treatment of Cardiac Hypertrophy

Anlin Luo, Jing Tan, Haisong Wang, Manman Yang, Shuojing Wang, Chengzeng Wang, Yachao Wang and Lin Liu

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202404201

Constructing bifunctional metal–organic framework based nanozymes with fluorescence and oxidase activity for the dual-channel detection of butyrylcholinesterase

Nan Wang, Jiyao Shi, Yuzhu Liu, Wenying sun and Xingguang Su

Analytica Chimica Acta, 2022, 1205, 339717
DOI: 10.1016/j.aca.2022.339717

Engineered bimetallic nanozyme-aptamer sensor for synergistic magnetic enrichment and colorimetric detection of exosomes

Yating Song, Xiaodong Lu, Peifang Chen, Gengli Huang, Yu Li, Zhouping Wang and Junsong Yang

Chemical Engineering Journal, 2025, 523, 168763
DOI: 10.1016/j.cej.2025.168763

Metal–Organic Frameworks (MOF)‐Based Nanozymes: Types, Engineering, and Recent Advances in Biosensing

Khatun A. Jannath and Md Mobarok Karim

Chemistry A European J, 2026
DOI: 10.1002/chem.71075

A cobalt-coordination polymer as a highly selective and sensitive luminescent sensor for detecting 2,4,6-trinitrophenol

Cuiping Wang, Wenwen Sheng, Chen Sun, Jie Lei and Jinsong Hu

Molecular Crystals and Liquid Crystals, 2024, 768, 117
DOI: 10.1080/15421406.2023.2262857

INVESTIGATION OF PEROXIDASE-MIMICKING PROPERTIES OF FeNiCo METAL-ORGANIC FRAMEWORK DECORATED MWCNT COMPOSITE NANOMATERIAL

Yudum Tepeli Büyüksünetçi

Mugla Journal of Science and Technology, 2025, 11, 1
DOI: 10.22531/muglajsci.1687954

Nanozyme engineering in structurally explicit framework: Design mechanisms and biosensing applications

Yanbin Xu, Anlian Huang, Wei Yi, Guosheng Chen, Siming Huang and Gangfeng Ouyang

Coordination Chemistry Reviews, 2024, 500, 215517
DOI: 10.1016/j.ccr.2023.215517

Metal–Organic Framework-Derived Nanozyme with Enhanced Laccase-like Activity for Capturing and Detection of Lead Ions

Shu Huang, Yihuan Gao, Yani Liu, Yupeng Guo, Jing Liu, Jianru Tang and Meiling Liu

ACS Appl. Nano Mater., 2025, 8, 24548
DOI: 10.1021/acsanm.5c04895

Newly Constructed NiCo2O4 Derived from ZIF-67 with Dual Mimic Enzyme Properties for Colorimetric Detection of Biomolecules and Metal Ions

Shi-Wen Lv, Ning Zhao, Jing-Min Liu, Fei-Er Yang, Chun-Yang Li and Shuo Wang

ACS Appl. Mater. Interfaces, 2021, 13, 25044
DOI: 10.1021/acsami.1c06705

Synthesis of Two-Dimensional (Cu–S)n Metal–Organic Framework Nanosheets Applied as Peroxidase Mimics for Detection of Glutathione

Yuan-Hsiang Yu, Xiao-Yuan Lin, Kun-Ling Teng, Wei-Fan Lai, Chia-Chi Hu, Chia-Hsuan Tsai, Ching-Ping Liu, Hui-Ling Lee, Cing-Huei Su, Yen-Hsiang Liu, Kuang-Lieh Lu and Su-Ying Chien

Inorg. Chem., 2023, 62, 17126
DOI: 10.1021/acs.inorgchem.3c02023

DNA flexible chain modified MOFs as a versatile platform for chemoenzymatic cascade reactions in glucose catalysis

Yuan Rao, Wei Zhuang, Jinle Liu, Ting Tang, Zhi Wang and Hanjie Ying

Enzyme and Microbial Technology, 2024, 173, 110352
DOI: 10.1016/j.enzmictec.2023.110352

Applications of Antimicrobial Photodynamic Therapy against Bacterial Biofilms

Sandile Phinda Songca and Yaw Adjei

IJMS, 2022, 23, 3209
DOI: 10.3390/ijms23063209

Organic Framework-Based Nanozymes: Design, Property, and Application

Feng Wang, Beidian Li, Mingtong Wang, Shuhao Huo, Bin Zou, Anzhou Ma, Guoqiang Zhuang and Ling Xu

Catalysts, 2026, 16, 223
DOI: 10.3390/catal16030223

Nanomaterials relieving hypoxia for enhanced tumor therapy

Lin Hao, Li Wang, Yichuan Ma, Massimo Bottini, Luwei Li, Hong-Bo Cheng, Shutao Gao, Xing-jie Liang and Jinchao Zhang

Coordination Chemistry Reviews, 2024, 499, 215482
DOI: 10.1016/j.ccr.2023.215482

Nanozyme-Driven Signal Amplification in Cancer Biosensing: Innovations Toward Precision and Point-of-Care Oncology

Victor Akpe and Ian E. Cock

Micromachines, 2026, 17, 541
DOI: 10.3390/mi17050541

Metal-organic frameworks for electrochemical glucose sensors: progress and challenges

Liyuan Wang, Shwu-Jen Chang, Ching-Jung Chen and Jen-Tsai Liu

Coordination Chemistry Reviews, 2025, 543, 216907
DOI: 10.1016/j.ccr.2025.216907

A dual-mode composite nanozyme-based cascade colorimetric-fluorescence aptasensor for Salmonella Typhimurium detection

Lijun Wang, Yi Li, Xin Yang, Hong Zhou, Xiao Yang and Xianggui Chen

Analytica Chimica Acta, 2024, 1324, 343116
DOI: 10.1016/j.aca.2024.343116

Substrate Specificity of Adenine‐Cu‐PO4 Nanozyme: Ascorbic Acid Oxidation and Selective Cytotoxicity

Mincong Yu, Yuanbo Gao, Yichen Liu, Zhuo Wang, Yang Zhang, Yunchao Li, Louzhen Fan and Xiaohong Li

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202403568

Synthesis and Characterization of Rubisco–Magnesium Complexes for Potential Gas Adsorption Applications

Gia Huy Pham, Elizabeth Willenborg, Emily Weber, Brandon Robinson and Cerasela Zoica Dinu

ACS Omega, 2026, 11, 4062
DOI: 10.1021/acsomega.5c08077

Peroxidase Mimic Sulfur‐Rich CuO‐Carbon Nitride Core‐Shell Nanorods for the Colorimetric Detection of Aminophenol Isomers

Muralikrishna Sreeramareddygari, Chatuporn Phanthong, Manjunath Krishnappa, Mithran Somasundrum and Werasak Surareungchai

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202300073

Bifunctional MOFs Nanozyme with Peroxidase Activity and Stimulus-responsive Fluorescent for Determination of Glyphosate

Yu-Meng Guo, Zi-Chong Chen, Kai-Xiang Zhang, Liu-Lu Liu, Chan Huang and Qing Li

J Fluoresc, 2024, 35, 6969
DOI: 10.1007/s10895-024-04057-1

Advances in Metal–Organic Framework-Based Nanozymes for Biosensing and Point-of-Care Testing Applications

Qingjie Fu, Shuo Tian, Shun Wang, Guoming Sun, Mengke Wang and Kelong Fan

ACS Appl. Nano Mater., 2025, 8, 17339
DOI: 10.1021/acsanm.5c02319

The Application of Metal–Organic Frameworks in Water Treatment and Their Large-Scale Preparation: A Review

Yuhang Xie, Teng Zhang, Bo Wang and Wenju Wang

Materials, 2024, 17, 1972
DOI: 10.3390/ma17091972

Revolutionizing nanozyme technology with metal-organic frameworks: Classification, catalytic mechanisms, regulation and applications in biotechnology

Yiran Wang, Yaqiong Yang, Jiachen Liu, Xiangyu Zi, Huayue Zhu, Xiaolong Sun, Yingjie Miao and Yongqian Fu

Chemical Engineering Journal, 2024, 500, 156850
DOI: 10.1016/j.cej.2024.156850

Flow-homogeneous electrochemical sensing system based on 2D metal-organic framework nanozyme for successive microRNA assay

Zhen Wang, Yucui Zhang, Xiuzhong Wang and Lei Han

Biosensors and Bioelectronics, 2022, 206, 114120
DOI: 10.1016/j.bios.2022.114120

From Nanozymes to Multi‐Purpose Nanomaterials: The Potential of Metal–Organic Frameworks for Proteomics Applications

Siene Swinnen, Francisco de Azambuja and Tatjana N. Parac‐Vogt

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202401547

A smartphone-integrated colorimetric quantitative analysis platform based on oxidase-like Ce(IV)-ATP-Tris CPNs/CNF test strip for detection of inorganic arsenic in rice

Linjie Wang, Juanli Yang, Yue Yan, Yuan-Song Zhang and Xuechao Xu

Analytica Chimica Acta, 2022, 1227, 340308
DOI: 10.1016/j.aca.2022.340308

An ultrasensitive electrochemical immunosensor for carcinoembryonic antigen detection based on two-dimensional PtPd/Cu-TCPP(Fe) nanocomposites

Jie Liu, Zixuan Zhang, Ying Li, Jie Dong and Chaorui Li

Anal Bioanal Chem, 2023, 415, 447
DOI: 10.1007/s00216-022-04425-5

Machine-Learning-Assisted Nanozyme-Based Sensor Arrays: Construction, Empowerment, and Applications

Jinjin Liu, Xinyu Chen, Qiaoqiao Diao, Zheng Tang and Xiangheng Niu

Biosensors, 2025, 15, 344
DOI: 10.3390/bios15060344

Introducing molecular imprinting onto nanozymes: toward selective catalytic analysis

Zhijian Bu, Lian Huang, Shu Li, Qingzhen Tian, Zheng Tang, Qiaoqiao Diao, Xinyu Chen, Jinjin Liu and Xiangheng Niu

Anal Bioanal Chem, 2024, 416, 5859
DOI: 10.1007/s00216-024-05183-2

Peroxidase-Like Activity of Silver Nanoparticles Loaded Filter Paper and its Potential Application for Sensing

Melisew Tadele Alula and Kuda Feke

J Clust Sci, 2023, 34, 613
DOI: 10.1007/s10876-021-02202-5

Highly Conjugated Nanozyme with Non Coordination Saturation for Cascaded Enhanced POD Reaction Driving Antibacterial Therapy

Mutian Yang, Youxing Liu, Ludan Zhang, Yuping Qian, Ningyu Li, Guanmeng Zhang, Yuxiang Hu, Xin Li, Yanjun Ge, Yang Peng, Jinna Ren, Yong Jiang, Shaojun Guo and Yuguang Wang

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202404894

Uniform stain pattern of robust MOF-mediated probe for flexible paper-based colorimetric sensing toward environmental pesticide exposure

Xinai Zhang, Zhuanlong Wang, Xiaowei Huang, Qilin Huang, Yunbo Wen, Bin Li, Melvin Holmes, Jiyong Shi and Xiaobo Zou

Chemical Engineering Journal, 2023, 451, 138928
DOI: 10.1016/j.cej.2022.138928

Spectrophotometric analysis of H 2 O 2 using Fe-based metal organic framework structures as peroxidase mimicking nanozymes: a comparative study

Vasfiye Hazal Özyurt and Ülkü Anik

Spectroscopy Letters, 2026, 1
DOI: 10.1080/00387010.2026.2655985

Tuning Oxygen Occupancy within Metal-Oxo Clusters for Enhancing Catalytic Activity of Zr-MOFs

Charlotte Simms, Angelo Mullaliu, Euan T. Sarson, Albert Solé-Daura, Jordi Puiggalí-Jou, Jorge J. Carbó, Giuliana Aquilanti and Tatjana N. Parac-Vogt

ACS Catal., 2025, 15, 14279
DOI: 10.1021/acscatal.5c03570

Gold Nanozymes: Smart Hybrids with Outstanding Applications

Sandra Jimenez-Falcao, Jose M. Méndez-Arriaga, Victoria García-Almodóvar, Antonio A. García-Valdivia and Santiago Gómez-Ruiz

Catalysts, 2022, 13, 13
DOI: 10.3390/catal13010013

In situ controllable growth of Ag particles on paper for smartphone optical sensing of Hg2+ based on nanozyme activity stimulation

Panwang Hu, Changkun Xia, Bangxiang Liu, Rulin Feng, Mengzhu Wang, Hengjia Zhu and Xiangheng Niu

Talanta, 2023, 253, 124055
DOI: 10.1016/j.talanta.2022.124055

Nanozyme-enabled microfluidic biosensors: A promising tool for on-site food safety analysis

Xiru Zhang, Danqing Zhu, Xinyan Yang, Chaoxin Man, Yujun Jiang, Qianyu Zhao and Xianlong Zhang

Trends in Food Science & Technology, 2024, 148, 104486
DOI: 10.1016/j.tifs.2024.104486

An Enzyme‐Encapsulated MOF@MOF Nanocomposite for Detecting H2O2 Derived From Superoxide Anion Released by Mitochondria of HeLa Cells

Jiaqi Niu, Xiaoxin Jin, Xingqi Wang, Zhenhua Ren, Bingjie Li, Xiaoqiang Liu and Danny K.Y. Wong

Small Methods, 2025, 9
DOI: 10.1002/smtd.202401070

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

Wen Liu, Ying Li, Yuanchao Wang and Yakai Feng

Small, 2024, 20
DOI: 10.1002/smll.202310249

UV-induced, nonenzymatic, H₂O₂-free colorimetric detection of Dopamine using MXene-based quasi-quantum dots

Rajapriya Govindaraju and Jongsung Kim

FlatChem, 2025, 54, 100966
DOI: 10.1016/j.flatc.2025.100966

Superoxide Dismutase‐like Activity of Zeolitic Imidazolate Framework Nanoparticles Comprising Biomimetic Imidazolato‐bridged CuZn Units

Hiroki Nakahara, Akiko Nomura, Shun Tokuda, Mami Okamura, Kiyoshi Fujisawa, Takanori Koitaya, Yasuhiro Yoshida, Shuhei Furukawa and Yutaka Hitomi

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202300881

Bioinspired synergy strategy based on the integration of nanozyme into a molecularly imprinted polymer for improved enzyme catalytic mimicry and selective biosensing

Abdelhafid Karrat and Aziz Amine

Biosensors and Bioelectronics, 2024, 266, 116723
DOI: 10.1016/j.bios.2024.116723

Recent Development of Bio-inspired Porous Materials for Catalytic Applications

Yongquan Tang, Ganggang Qi, Sai Wang, Xiangju Meng and Feng-Shou Xiao

Chem. Res. Chin. Univ., 2023, 39, 13
DOI: 10.1007/s40242-022-2164-0

Ratiometric Colorimetric Detection of Nitrite Realized by Stringing Nanozyme Catalysis and Diazotization Together

Mengzhu Wang, Peng Liu, Hengjia Zhu, Bangxiang Liu and Xiangheng Niu

Biosensors, 2021, 11, 280
DOI: 10.3390/bios11080280

Metal-organic framework-based advanced therapeutic tools for antimicrobial applications

Zhao Chen, Fei Xing, Peiyun Yu, Yuxi Zhou, Rong Luo, Ming Liu and Ulrike Ritz

Acta Biomaterialia, 2024, 175, 27
DOI: 10.1016/j.actbio.2023.12.023

Self-Assembled Pd12 Coordination Cage as Photoregulated Oxidase-Like Nanozyme

Soumalya Bhattacharyya, Sk Rajab Ali, Mangili Venkateswarulu, Prodip Howlader, Ennio Zangrando, Mrinmoy De and Partha Sarathi Mukherjee

J. Am. Chem. Soc., 2020, 142, 18981
DOI: 10.1021/jacs.0c09567

Facile Synthesis of Enzyme-Mimicking Cobalt-Polyphenol Coordination Network for Oxidation of Phenolic Pollutants

Tarun Kumar Sahu, Ankit Gupta, Vidhi Agarwal and Tridib K. Sarma

ACS Appl. Eng. Mater., 2023, 1, 3194
DOI: 10.1021/acsaenm.3c00487

Hydrolytic nanozymes: Preparation, properties, and applications

Tianyou Chen, Yizhuo Lu, Xiaorong Xiong, Meishuang Qiu, Yan Peng and Zushun Xu

Advances in Colloid and Interface Science, 2024, 323, 103072
DOI: 10.1016/j.cis.2023.103072

Recent advances of nanozyme-enhanced lateral flow assay sensing in clinic diagnosis

Haoxuan Xiong, Peipei Hu, Meimei Zhang, Yanping Li and Zhenqiang Ning

Microchemical Journal, 2024, 206, 111602
DOI: 10.1016/j.microc.2024.111602

Peroxide-Free Hexavalent Chromium Detection via Surface Electron Transfer in a Redox-Active Bismuth Metal–Organic Framework Nanozyme

Sivasankar Kulandaivel, Yi-Ning Wang, Dinesh Kumar Dhanthala Chittibabu, Yung-Kang Lu, Hsin-Tsung Chen and Yi-Chun Yeh

ACS Appl. Nano Mater., 2025, 8, 13060
DOI: 10.1021/acsanm.5c02135

Colorimetric detection of cancer biomarker by using porous Mn–N–C single-atom nanozyme with peroxidase-like activity

Hojeong Shin, Jiwon Woo, Seongin Hong, Soeun Yoo, Hyeonwoo Cho, Byung Hee Hong, Yun Jeong Hwang and Dal-Hee Min

Talanta, 2025, 292, 127946
DOI: 10.1016/j.talanta.2025.127946

A novel copper-carboxyphosphinate with biomimetic peroxidase and antibacterial activities

Yuxin Jiang, Ze-Yu Wang, Li-Na Wu, Jian-Bo Liu, Yongmei Zhao and Zhao-Xi Wang

Polyhedron, 2025, 282, 117781
DOI: 10.1016/j.poly.2025.117781

Multimetallic nanoparticles decorated metal-organic framework for boosting peroxidase-like catalytic activity and its application in point-of-care testing

Pian Wu, Fangjie Gong, Xiangling Feng, Yong Xia, Lehuan Xia, Tianhan Kai and Ping Ding

J Nanobiotechnol, 2023, 21
DOI: 10.1186/s12951-023-01946-8

Recent Development of Copper‐Based Nanozymes for Biomedical Applications

Xin Yu, Yawen Wang, Jian Zhang, Jing Liu, Aizhu Wang and Longhua Ding

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202302023

Tailoring metal-organic frameworks-based nanozymes for bacterial theranostics

Arbab Ali, Muhammad Ovais, Huige Zhou, Yukui Rui and Chunying Chen

Biomaterials, 2021, 275, 120951
DOI: 10.1016/j.biomaterials.2021.120951

Bimetallic Metal–Organic Frameworks: Enhanced Peroxidase-like Activities for the Self-Activated Cascade Reaction

Xiaoping Zhao, Ning Zhang, Tingting Yang, Daomeng Liu, Xunan Jing, Daquan Wang, Zhiwei Yang, Yunchuan Xie and Lingjie Meng

ACS Appl. Mater. Interfaces, 2021, 13, 36106
DOI: 10.1021/acsami.1c05615

Analyte-triggered citrate-stabilized Au nanoparticle aggregation with accelerated peroxidase-mimicking activity for catalysis-based colorimetric sensing of arsenite

Qiangsheng Xue, Xiangheng Niu, Peng Liu, Mengzhu Wang, Yinxian Peng, Hongbing Peng and Xin Li

Sensors and Actuators B: Chemical, 2021, 334, 129650
DOI: 10.1016/j.snb.2021.129650

Analyte-triggered oxidase-mimetic activity loss of Ag3PO4/UiO-66 enables colorimetric detection of malathion completely free from bioenzymes

Peng Liu, Xin Li, Xuechao Xu, Xiangheng Niu, Mengzhu Wang, Hengjia Zhu and Jianming Pan

Sensors and Actuators B: Chemical, 2021, 338, 129866
DOI: 10.1016/j.snb.2021.129866

Cu-based materials: Design strategies (hollow, core-shell, and LDH), sensing performance optimization, and applications in small molecule detection

Wenbin Cao, Tong Guo, Jialiang Wang, Guangyu Xu, Jizhou Jiang and Dong Liu

Coordination Chemistry Reviews, 2023, 497, 215450
DOI: 10.1016/j.ccr.2023.215450

A high selectively and sensitively fluorescent uranium metal-organic framework for sensing nitro aromatic compounds in aqueous media

Sixin Yang, Jinsong Hu, Jing Zhang, Tianci He, Longyu Zhang and Hong Chen

Inorganica Chimica Acta, 2022, 536, 120914
DOI: 10.1016/j.ica.2022.120914

Construction of the fluorescence sensing platform with a bifunctional Cu@MOF nanozyme for determination of alkaline phosphatase and its inhibitor

Yuhan Chen, Nan Wang, Yuntai Lv, Chenyu Zhou, Qing Liang and Xingguang Su

Talanta, 2024, 278, 126564
DOI: 10.1016/j.talanta.2024.126564

Multifunctional nanozymes for disease diagnosis and therapy

Qingzhi Han, Di Huang, Sijie Li, Bing Xia and Xiaoyu Wang

Biomedical Journal, 2024, 47, 100699
DOI: 10.1016/j.bj.2024.100699

Dual-functional trimetallic nanozyme with computation-aided interpretation for synergistic degradation and detection of tetracycline antibiotics

Xingyue Liu, Yuanqiu Lai, Yue Gao, Weijian Cheng, Jiahao Xu, Jia-Wei Shen, Jingbin Zeng and Wei Duan

Journal of Hazardous Materials, 2025, 499, 140264
DOI: 10.1016/j.jhazmat.2025.140264

Biocompatible Folic-Acid-Strengthened Ag–Ir Quantum Dot Nanozyme for Cell and Plant Root Imaging of Cysteine/Stress and Multichannel Monitoring of Hg2+ and Dopamine

Zhengquan Yan, Yulian Tang, Zhaoran Zhang, Jing Feng, Junkai Hao, Shuo Sun, Meng Li, Yuguang Song, Wei Dong and Lei Hu

Anal. Chem., 2024, 96, 4299
DOI: 10.1021/acs.analchem.4c00081

Polyphenolic antioxidant analysis using metal organic Frameworks: Theoretical foundations and practical applications

Alaa Bedair, Mahmoud Hamed, Sameera Sh. Mohammed Ameen, Khalid M. Omer and Fotouh R. Mansour

Microchemical Journal, 2024, 205, 111183
DOI: 10.1016/j.microc.2024.111183

Metal-organic frameworks and their composites for the adsorption and sensing of phosphate

Elmehdi Moumen, Loubna Bazzi and Samir El Hankari

Coordination Chemistry Reviews, 2022, 455, 214376
DOI: 10.1016/j.ccr.2021.214376

Current advances in metal–organic frameworks for cancer nanodynamic therapies

Zhu Liu, Ziwei Yan, Yifan Di, Shuqian Yang, Yingyi Ning, Yuling Mao, Yikun Gao, Qinfu Zhao and Siling Wang

Coordination Chemistry Reviews, 2023, 497, 215434
DOI: 10.1016/j.ccr.2023.215434

MOF-On-MOF Dual Enzyme-Mimic Nanozyme with Enhanced Cascade Catalysis for Colorimetric/Chemiluminescent Dual-Mode Aptasensing

Huining Chai, Kun Yu, Yiming Zhao, Ziyan Zhang, Shasha Wang, Chaonan Huang, Xueji Zhang and Guangyao Zhang

Anal. Chem., 2023, 95, 10785
DOI: 10.1021/acs.analchem.3c01905

Metal–organic frameworks (MOFs) based chemosensors/biosensors for analysis of food contaminants

Zhihong Zhang, Yafei Lou, Chuanpan Guo, Qiaojuan Jia, Yingpan Song, Jia-Yue Tian, Shuai Zhang, Minghua Wang, Linghao He and Miao Du

Trends in Food Science & Technology, 2021, 118, 569
DOI: 10.1016/j.tifs.2021.10.024

Two Birds, One Stone: Smart MOF Nanozymes for Dual Catalysis and Theranostics

Mohammed Ali Dheyab, Wesam Abdullah, Azlan Abdul Aziz, Nik Noor Ashikin Nik Ab Razak, Nursakinah Suardi, Saleh T. Alanezi, Mahmood S. Jameel, Farhank Saber Braim, Firas Fohely, Pegah Moradi Khaniabadi, Nazila Oladzadabbasabadi and Mehran Ghasemlou

Small, 2025, 21
DOI: 10.1002/smll.202509992

A fluorescent nanozyme ZIF-8@CuNCs with hydrolase-like activity for the dual-mode sensing of fenitrothion

Jiatong Li, Jie Li, Jiakang Hu, Yongxin Li and Hui Huang

Sensors and Actuators B: Chemical, 2025, 442, 138163
DOI: 10.1016/j.snb.2025.138163

Recent progress in the construction and applications of metal-organic frameworks and covalent-organic frameworks-based nanozymes

Limin Zheng, Fangqi Wang, Chenrui Jiang, Sijing Ye, Jinzhe Tong, Pierre Dramou and Hua He

Coordination Chemistry Reviews, 2022, 471, 214760
DOI: 10.1016/j.ccr.2022.214760

AgAu-modified quasi-MIL-53 hybrid nanozymes with triple enzyme-like activities for boosting biocatalytic disinfection

Sheng Zhong, Fayin Mo, Linxi Chen, Weiwei Qin, Luyong Zhang, Jing Lu and Duanping Sun

Journal of Colloid and Interface Science, 2024, 661, 520
DOI: 10.1016/j.jcis.2024.01.190

Nanosensor based approaches for quantitative detection of heparin

Aakanksha Pathak, Nishchay Verma, Shweta Tripathi, Amit Mishra and Krishna Mohan Poluri

Talanta, 2024, 273, 125873
DOI: 10.1016/j.talanta.2024.125873

Rapid mechanochemical production of biocomposites by encapsulating enzymes to zinc based-two metal organic frameworks (ZIF-8 and Zn-MOF-74) for enantioselective hydrolysis reaction of racemic Naproxen methyl ester

Elif Ozyilmaz and Ozge Caglar

Process Biochemistry, 2023, 134, 276
DOI: 10.1016/j.procbio.2023.10.002

Molecular Network-Bearing Fe–N–C Single-Atom Nanozymes for Monitoring Intracellular Glutathione Fluctuations

Chunqi Cai, Wen Chen, Chengyang Zhu, Pengcheng Huang, Fang-Ying Wu, Ke-Yu Deng and Junjie Mao

ACS Appl. Nano Mater., 2024, 7, 9507
DOI: 10.1021/acsanm.4c00987

Catalysis in Chemical Modification of Proteins

Seiya Ishizawa, Koki Fujimura, Kounosuke Oisaki, Shinichi Sato and Jun Ohata

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202402125

Functional catalytic nanoparticles (nanozymes) for sensing

Yu Ouyang, Michael P. O'Hagan and Itamar Willner

Biosensors and Bioelectronics, 2022, 218, 114768
DOI: 10.1016/j.bios.2022.114768

Nanozyme biosensors: Catalytic mechanism, activity regulation, signal amplification and application in food analysis

Xiaonan Ma, Ganchao Sun, Aoxue Leng, Xiaobo Wei, Junnan Xu, Wei Ding, Huiyan Liu and Haitian Fang

Talanta, 2026, 296, 128398
DOI: 10.1016/j.talanta.2025.128398

Recent Advances in Phosphatase-Mimetic Nanozymes for Analytical Sensing

Yuxuan Long, Yuxuan Yao, Ruihan Zou, Qingzhen Tian, Jinjin Liu, Dan Du, Xiangheng Niu and Yuehe Lin

ECS Sens. Plus, 2026, 5, 020601
DOI: 10.1149/2754-2726/ae5bc8

Recent advances in single-atom nanozymes for colorimetric biosensing

Zhaoyuan Lyu, Jiachi Zhou, Shichao Ding, Dan Du, Joseph Wang, Yun Liu and Yuehe Lin

TrAC Trends in Analytical Chemistry, 2023, 168, 117280
DOI: 10.1016/j.trac.2023.117280

Metalloporphyrin and gold nanoparticles modified hollow zeolite imidazole Framework-8 with excellent peroxidase like activity for quick colorimetric determination of choline in infant formula milk powder

Haizhi Zhang, Hongyuan Wu, Xinguang Qin, Ying Shen, Xinlin Wei and Gang Liu

Food Chemistry, 2022, 384, 132552
DOI: 10.1016/j.foodchem.2022.132552

Construction of a bioinspired Fe3O4/N-HCS nanozyme for highly sensitive detection of GSH

Yanning Zheng, Dapeng Xu, Lixia Sun, Junrong Ji, Jianhua Sun, Zhangfa Tong, Lingyi Qin, Youquan Zhang, Jiangxue Luo and Dankui Liao

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 648, 129046
DOI: 10.1016/j.colsurfa.2022.129046

Photocatalytic CO2‐to‐Syngas Evolution with Molecular Catalyst Metal‐Organic Framework Nanozymes

Philip M. Stanley, Alice Y. Su, Vanessa Ramm, Pascal Fink, Ceren Kimna, Oliver Lieleg, Martin Elsner, Johannes A. Lercher, Bernhard Rieger, Julien Warnan and Roland A. Fischer

Advanced Materials, 2023, 35
DOI: 10.1002/adma.202207380

Preparation and applications of metal-organic framework derived porous carbons as novel adsorbents in sample preparation

Huixiao Duo, Xiaofeng Lu, Shuai Wang, Xiaojing Liang and Yong Guo

TrAC Trends in Analytical Chemistry, 2020, 133, 116093
DOI: 10.1016/j.trac.2020.116093

A nanozyme-based enzyme-linked immunosorbent assay method for the detection of MRGPRX2 in human peripheral blood serum

Nannan Ren, Ping Wang, Chao Wang, Liyun Kong and Jiangang Long

Microchemical Journal, 2026, 220, 116696
DOI: 10.1016/j.microc.2025.116696

Recent progress in MOFs-based nanozymes for biosensing

Imamdin Chandio, Yongjian Ai, Lei Wu and Qionglin Liang

Nano Res., 2024, 17, 39
DOI: 10.1007/s12274-023-5770-3

Enzyme Mimics for Engineered Biomimetic Cascade Nanoreactors: Mechanism, Applications, and Prospects

Xianlong Zhang, Guoliang Li, Guang Chen, Di Wu, Yongning Wu and Tony D. James

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202106139

Cu-PyC MOF with oxidoreductase-like catalytic activity boosting colorimetric detection of Cr(VI) on paper

Sivasankar Kulandaivel, Wen-Chi Lo, Chia-Her Lin and Yi-Chun Yeh

Analytica Chimica Acta, 2022, 1227, 340335
DOI: 10.1016/j.aca.2022.340335

Recent Advances in Metal–Organic Framework Nanozyme (MOFzyme)-Based Biosensors for Detecting Food Contaminants

Shipeng Gao, Qing Sun, Jaroslav Katona, Di Zhang, Yang Zhang and Xiaobo Zou

J. Agric. Food Chem., 2025, 73, 23045
DOI: 10.1021/acs.jafc.5c06078

A comprehensive review of nanozyme construction strategies and their applications in environmental analysis

Samar H. Elagamy, Reem H. Obaydo, Abdulsalam Ashkar and Hayam M. Lotfy

Sensors and Actuators Reports, 2025, 10, 100394
DOI: 10.1016/j.snr.2025.100394

Research Progress on the Application of Nanozymes in Biosensors

Qijia Jiang, Jiaqi Xiao, Keying Ling, Hongying Zhu, Guizhang Wang, Yu Li, Penghao Yu, Zixuan Wang, Bohao Li and Shuang Zou

srb, 2026, 2, 37
DOI: 10.71052/srb2024/YHOA1437

Incorporation of Fluorescent Carbon Quantum Dots into Metal–Organic Frameworks with Peroxidase-Mimicking Activity for High-Performance Ratiometric Fluorescent Biosensing

Qiuyu Ye, Tao Dai, Jin Shen, Qin Xu, Xiaoya Hu and Yun Shu

J. Anal. Test., 2023, 7, 16
DOI: 10.1007/s41664-022-00246-8

Catalytic imaging-guided cancer therapy using non-coordinated and coordinated nanozymes

Mojtaba Falahati, Majid Sharifi, Yasaman Vahdani, Setareh Haghighat, Timo L.M. ten Hagen and Yu Cai

Coordination Chemistry Reviews, 2024, 507, 215755
DOI: 10.1016/j.ccr.2024.215755

Silver-Based Bimetallic Metal-Organic Frameworks Nanomaterials for Rapid and Collaborative Sterilization

Li Xi, Mengyuan Xu, Jiehan Chen, Huiying Zheng and Tian Liu

SSRN Journal, 2022
DOI: 10.2139/ssrn.4010424

A Sensitive and Selective Colorimetric Method Based on the Acetylcholinesterase-like Activity of Zeolitic Imidazolate Framework-8 and Its Applications

Guo-Ying Chen, Zheng-Ming Qian, Shi-Jun Yin, Xi Zhou and Feng-Qing Yang

Molecules, 2022, 27, 7491
DOI: 10.3390/molecules27217491

Nanozymes-Mediated Lateral Flow Assays for the Detection of Pathogenic Microorganisms and Toxins: A Review from Synthesis to Application

Sofiene Mansouri

Critical Reviews in Analytical Chemistry, 2025, 1
DOI: 10.1080/10408347.2025.2491683