Themed collection Microfluidic Systems for Addressing Energy Challenges


Mine-on-a-chip: megascale opportunities for microfluidics in critical materials and minerals recovery
The rising demand for mineral resources essential to the functionality of low-carbon energy technologies—critical minerals—and the security of their supply cause one of the most pressing bottlenecks in the journey toward energy sustainability.
Lab Chip, 2025,25, 4461-4472
https://doi.org/10.1039/D5LC00387C

Interfacial electro-hydrodynamics inspired micro/nano-fluidic energy conversion: from mechanism to applications
This review summarizes recent advances in interfacial electro-hydrodynamic micro/nano-fluidic energy harvesting strategies from water, and highlights their promising applications in power sources and self-powered devices.
Lab Chip, 2025,25, 4161-4220
https://doi.org/10.1039/D5LC00321K

Microfluidics for geosciences: metrological developments and future challenges
This review addresses the main metrological developments over the past decade for microfluidics applied to geosciences.
Lab Chip, 2025,25, 4273-4289
https://doi.org/10.1039/D5LC00108K
Advancing sustainable energy solutions with microfluidic porous media
Multiphase reactive flow in sustainable energy solutions (CCS, UHS, NWGD), coupling the multiphase flow, reactive transport, and microbial activities. The internal schematic diagram is the subsurface storage of CO2, H2, and nuclear waste.
Lab Chip, 2025,25, 3374-3410
https://doi.org/10.1039/D5LC00206K

A review of microfluidic approaches for carbon capture and storage research
This review highlights microfluidics as a disruptive platform for advancing carbon capture and storage, enabling rapid testing, enhanced mass transfer, and precise flow control while offering insight into mechanisms, tools, and design strategies.
Lab Chip, 2025, Advance Article
https://doi.org/10.1039/D5LC00208G

Calcite-functionalized microfluidic chip for pore scale investigation of biogeochemical interactions in porous media
This study introduces a method for in situ, site-selective calcite growth, enhancing micromodels for studying microbial-fluid–rock interactions.
Lab Chip, 2025,25, 2320-2324
https://doi.org/10.1039/D5LC00105F
A hybrid flowing water-based energy generator inspired by a rotatable waterwheel
A hybrid rotatable flowing water-based energy generator fully utilizes the spatial decoupling of the gravitational force of flowing water in two orthogonal directions and renders efficient water energy harvesting across a wide range of flow rates.
Lab Chip, 2025, Advance Article
https://doi.org/10.1039/D5LC00476D
Integrated physics-based modeling and microfluidics for quantifying multiphase carbonate dissolution in rocks
Novel framework integrates rock-embedded microfluidics, ML-enabled image analysis and physics modeling. New conceptual model to quantify gas shielding effects on rock dissolution reactions and calculation of reaction rates from time-resolved images.
Lab Chip, 2025, Advance Article
https://doi.org/10.1039/D5LC00557D
Microchannel-confined droplet-based electricity generator for biomechanical energy conversion and sensing
A flexible microchannel-confined droplet-based electricity generator (MC-DEG) is proposed, enabling biomechanical energy conversion and physiological signal monitoring.
Lab Chip, 2025, Advance Article
https://doi.org/10.1039/D5LC00662G
Pore-scale mechanisms of salt precipitation in heterogeneous media under geological carbon storage conditions
Overview of pore-scale investigation of salt precipitation: (a) the microfluidic device showing details, (b) magnified heterogeneous regions with more permeable region in the middle, (c) precipitated salts in dark grey with brine and CO2 labeled.
Lab Chip, 2025, Advance Article
https://doi.org/10.1039/D5LC00696A

Mechanistic understanding of carbon mineralization in fracture systems using microfluidics
High-pressure microfluidics reveal how fracture flow dynamics control dissolution–precipitation pathways, providing insights into optimizing permanent geologic carbon storage in mafic and ultramafic rock systems.
Lab Chip, 2025,25, 4024-4037
https://doi.org/10.1039/D5LC00178A
Impact of multiphasic pore-scale interactions on gas hydrate formation and dissociation characteristics and kinetics: a microfluidic study
Microfluidic observation with methylene blue enhanced gas–water–hydrate phase distinction, revealing five hydrate morphologies shaped by multiphase interactions and showing that gas contact significantly accelerates hydrate dissociation.
Lab Chip, 2025,25, 3741-3765
https://doi.org/10.1039/D5LC00093A

Rock-on-a-chip: a novel method for designing representative microfluidic platforms based on real rock structures and pore network modelling
We developed a workflow to create quasi-2D microfluidic chips that replicate rock pore structures from 3D CT data. This method preserves pore morphology and size distributions, enhancing microfluidic studies for carbon utilization and storage.
Lab Chip, 2025,25, 3109-3122
https://doi.org/10.1039/D5LC00119F

Rapid screening of CO2 capture fluids
High-throughput evaluation of CO2 capture fluids accelerates the development of next-gen carbon capture technologies.
Lab Chip, 2025,25, 2918-2925
https://doi.org/10.1039/D4LC00772G

CO2 hydrate nucleation study: novel high-pressure microfluidic devices
Schematics and optical view of the droplet trap chip.
Lab Chip, 2025,25, 2903-2917
https://doi.org/10.1039/D4LC01102C
Ignition of non-equilibrium methane dielectric barrier discharges in a multiphase plasma–liquid microfluidic device
Combined analysis of optical emission spectroscopy and infrared thermography revealing how liquid properties affect plasma ignition in a dielectric barrier discharge microfluidic system where methane-containing gas interacts with organic liquids.
Lab Chip, 2025,25, 2182-2192
https://doi.org/10.1039/D5LC00090D
Visualization investigation of fluid transport in multiscale porous media for CO2-EOR based on microfluidic technology
Visualizing CO2-EOR dynamics: Left—schematic of CO2 injection in reservoir pores. Right—in situ observations of oil displacement in microfluidic chips. Cross-scale effects boost miscible recovery to 100% but worsen channeling in immiscible floods.
Lab Chip, 2025,25, 1981-1992
https://doi.org/10.1039/D5LC00019J
Luffa cylindrica-inspired powerless micropump: long-term, high-flow operation and energy-generation application
A biomimetic micropump inspired by Luffa cylindrica enhances passive fluid transport by integrating a hierarchical porous aerogel and flow resistors, enabling controlled and sustained operation for microfluidics and energy generation applications.
Lab Chip, 2025,25, 1968-1980
https://doi.org/10.1039/D5LC00068H
About this collection
Achieving a sustainable future is one of the greatest challenges facing our society today which requires to be imperatively addressed. To ensure this for current and future generations, with minimal or zero net carbon emissions in matching a higher-than-ever energy demand, we must undertake a comprehensive overhaul of our energy systems.
Lab-on-a-chip systems hold opportunities in addressing this challenge through their potential to provide deep and unique understanding of the essential physical and geochemical mechanisms underlying innovative technologies that are crucial for this societal transition. Additionally, they can facilitate the development of relevant and necessary new processes and materials.
In this Thematic Collection led by Thought Leader Tony Kovscek, we aim to showcase cutting-edge advancements in micro/nanofluidics and lab-on-a-chip devices that can address critical energy challenges, paving the way for a sustainable future.
Topics of particular interest include, but are not limited to, innovations that emphasise the role of microfluidic/nanofluidic/miniaturised systems and their applications in:
• hydrogen/energy storage
• geothermal energy extraction
• bioenergy
• energy generation/conversion
• engineered nanoporous materials
• carbon sequestration
• critical material/mineral recovery
• water filtration and remediation