This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
The transition metal catalyzed cycloaddition reaction is one of the most powerful tools for the construction of carbon- and heterocycles. DFT studies are performed to investigate the mechanism of the Ni-catalyzed intramolecular [4 + 2] cycloaddition.
A highly enantioselective palladium-catalyzed hydrosilylation reaction of prochiral 1,1-disubstituted cyclopropenes to access a wide variety of silylcyclopropanes bearing a quaternary carbon-stereocenter with good diastereo- and enantioselectivities.
γ-Lactam is obtained from cyclobutanones using oxime reagents in the presence of a catalytic amount of Brønsted acid under mild conditions via transoximation and the Beckmann rearrangement mechanism.
This review summaries the advances in Au-catalyzed asymmetric alkyne transformations over the past two decades. It is organized by the key intermediates and the chirality induction models, offering a toolkit for the implement of asymmetric catalysis.