Exploring the latest trends in chemistry, structure, coordination, and diverse applications of 1-acyl-3-substituted thioureas: a comprehensive review

Sayyed Aqib Ullah, Aamer Saeed, Muhammad Azeem, Mian Bilal Haider and Mauricio F. Erben

RSC Adv., 2024, 14, 18011
DOI: 10.1039/D4RA02567A

Investigation of Newly Synthesized Bis-Acyl-Thiourea Derivatives of 4-Nitrobenzene-1,2-Diamine for Their DNA Binding, Urease Inhibition, and Anti-Brain-Tumor Activities

Nasima Arshad, Uzma Parveen, Pervaiz Ali Channar, Aamer Saeed, Waseem Sharaf Saeed, Fouzia Perveen, Aneela Javed, Hammad Ismail, Muhammad Ismail Mir, Atteeque Ahmed, Basit Azad and Ishaq Khan

Molecules, 2023, 28, 2707
DOI: 10.3390/molecules28062707

Investigations of Limeum Indicum Plant for Diabetes Mellitus and Alzheimer's Disease Dual Therapy: Phytochemical, GC‐MS Chemical Profiling, Enzyme Inhibition, Molecular Docking and In‐Vivo Studies

Tahira Shamim, Hafiz Muhammad Asif, Syeda Abida Ejaz, Zahid Hussain, Tanveer A. Wani, Laila Sumreen, Muhammad Abdullah, Zubair Ahmed, Jamshed Iqbal, Song Ja Kim and Muhammad Kamal Shah

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202301858

Green synthesis of nitroaryl thioureas: Towards an improved preparation of guanidinium DNA binders

Marco Minneci, Matas Misevicius and Isabel Rozas

Bioorganic & Medicinal Chemistry Letters, 2023, 90, 129346
DOI: 10.1016/j.bmcl.2023.129346

Exploration of newly synthesized amantadine-thiourea conjugates for their DNA binding, anti-elastase, and anti-glioma potentials

Nasima Arshad, Muhammad Shakeel, Aneela Javed, Fouzia Perveen, Aamer Saeed, Atteeque Ahmed, Hammad Ismail, Pervaiz Ali Channar and Fatima Naseer

International Journal of Biological Macromolecules, 2024, 263, 130231
DOI: 10.1016/j.ijbiomac.2024.130231

Computational and experimental structural analysis of 3-benzoyl-1,1-dimethyl-thiourea and its polymorph

Oluwatoyin Akerele and Andreas Lemmerer

Struct Chem, 2025, 36, 2097
DOI: 10.1007/s11224-025-02489-4

Quantitative N–S chelation speciation and pH-dependent selectivity of Pb(II) and Cu(II) on thiourea-functionalized rice husk cellulose under extreme proton competition (pH 2): An XPS-based analytical study

El-Sh Ibrahim, Nahla A. Taha, Mai Sheta and Mahmoud M. Elewa

Talanta, 2026, 307, 129923
DOI: 10.1016/j.talanta.2026.129923

Acylthiourea ligands in Ru(II)–arene chemistry: Coordination modes, structural insights, solvent and pH effects

Amir Karim, Rahime Eshaghi Malekshah, Najeeb Ullah and Sodio C.N. Hsu

Inorganica Chimica Acta, 2026, 594, 123077
DOI: 10.1016/j.ica.2026.123077

Synthesis, X-Ray crystallography and HF/DFT analysis of N(diethylcarbamothioyl) furan-2-carboxamide, analyzed by experimental and theoretical methods

Aamer Saeed, Saba Ashraf, Ghulam Shabir, Tuncer Hökelek, Ulrich Flörke, Asma Mukhtar and Muhammad Saeed

Journal of Molecular Structure, 2022, 1268, 133721
DOI: 10.1016/j.molstruc.2022.133721

Evaluation of Synthetic Aminoquinoline Derivatives As Urease Inhibitors: In Vitro , In Silico and Kinetic Studies

Faiza Seraj, Khalid Mohammed Khan, Jamshed Iqbal, Aqeel Imran, Zahid Hussain, Uzma Salar, Shehryar Hameed and Muhammad Taha

Future Med. Chem., 2023, 15, 1703
DOI: 10.4155/fmc-2023-0168

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

Nuno Martinho and Natália Aniceto

ChemMedChem, 2026, 21
DOI: 10.1002/cmdc.202500423

An Efficient Synthesis of New N‐Aryl‐N'‐Acyl Thiourea Derivatives and Their Antimicrobial Activity, Cytotoxicity, and In Silico Studies

Nilesh Sakhare, Prasanna Joshi, Manish Bhoye, Kiran Kharad, Pravin Mhaske, Sushma Takate and Sadhana Mhaske

ChemistrySelect, 2026, 11
DOI: 10.1002/slct.202506812

Facile synthesis, crystal structure, biological evaluation, and molecular modeling studies of N-((4-acetyl phenyl) carbamothioyl) pivalamide as the multitarget-directed ligand

Aamer Saeed, Syeda Abida Ejaz, Aqsa Khalid, Pervaiz Ali Channar, Mubashir Aziz, Tanveer A. Wani, Seema Zargar, Sidra Hassan, Hammad Ismail, Dania Khalid, Muhammad Zaffar Hashmi, Tuncer Hökelek and Abdullahi Tunde Aborode

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.992701

Neutral and cationic Ru(II)-p-cymene complexes containing acylthiourea ligands: antibacterial activity and insights into the electronic and structural properties

Marcielli Indiara de Oliveira, Aryane de Azevedo Pinheiro, Vinícius Acir Glitz, Jessica de Bona, Sailer Santos dos Santos, Luis Henrique da Silveira Lacerda, Adailton João Bortoluzzi, Alda Karine Medeiros Holanda, Márcio Peres de Araujo and Juliana Paula da Silva

Journal of Molecular Structure, 2026, 1350, 144019
DOI: 10.1016/j.molstruc.2025.144019

Design, Synthesis, and Bioevaluation of Adamantane‐1‐Carboxamide N‐Acylthioureas for Airway Antiallergic Therapy

Rahime Eshaghi Malekshah, Amir Karim, Chi‐Xin Guo, Yu‐Ting Chu, Feng‐Ming Yang, Sung‐Po Hsu and Sodio C. N. Hsu

ChemBioChem, 2026, 27
DOI: 10.1002/cbic.202500756

Synthesis, X-ray crystal structures, spectroscopic characterization, DFT calculations, and molecular docking study of new N -(4-chlorobutanoyl)- N’ -(2-, 3-, and 4-methoxyphenyl)thiourea derivatives

Hamza M. Abosadiya, El Hassane Anouar and Bohari M. Yamin

Phosphorus, Sulfur, and Silicon and the Related Elements, 2025, 200, 1054
DOI: 10.1080/10426507.2025.2574290

Amino Acid‐Based Cinnamoyl Thiourea Ligands and Their Copper(II) Complexes: Synthesis, in Silico, and Antibacterial Evaluation

Brandon Sanday Mominn and Maya Asyikin Mohamad Arif

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202502754

A new chalcone derivative: Synthesis, crystal structure, Hirshfeld surface, quantum chemical investigations, Druggability and human Cathepsin D inhibitory activity

Ya-an Zhang, Xiaowan Wang, Ya-dian Pan, Xin-Zhu She, Yuan-Yuan Liu and Bai-Wang Sun

Journal of Molecular Structure, 2025, 1324, 140854
DOI: 10.1016/j.molstruc.2024.140854

Phytochemical profiling, antioxidant, and enzyme inhibition studies of Dipterygium glaucum extracts with relevance to diabetes mellitus and Alzheimer’s disease

Tahira Shamim, Syeda Abida Ejaz, Hafiz Muhammad Asif, Tanveer A. Wani, Muhammad Abdullah, Laila Sumreen, Seema Zargar and Song Ja Kim

Proc.Indian Natl. Sci. Acad., 2026
DOI: 10.1007/s43538-025-00657-y