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Homogenization offers access to quinoxalines in minutes: a solvent-free, catalyst-free protocol with a near-zero E-factor

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RSC Mechanochem., 2025, 2, 72
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A Review on Multipurpose Potential of Bioactive Heterocycle Quinoxaline

Gita Chawla, Ojasvi Gupta and Tathagata Pradhan

ChemistrySelect, 2023, 8
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Fragment-based QSAR study to explore the structural requirements of DPP-4 inhibitors: a stepping stone towards better type 2 diabetes mellitus management

P.K. Dey, R. Dutta, M. Ray, P. Jakkula, S. Banerjee, I.A. Qureshi, S. Gayen and S.A. Amin

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Recent advances and structure-activity relationship studies of DPP-4 inhibitors as anti-diabetic agents

Shipra Singhal, Vaishali Manikrao Patil, Saroj Verma and Neeraj Masand

Bioorganic Chemistry, 2024, 146, 107277
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Synthetic Approaches to Novel DPP-IV Inhibitors—A Literature Review

Valentin Petrov, Teodora Aleksandrova and Aleksandar Pashev

Molecules, 2025, 30, 1043
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Coumarin-Based Sulfonamide Derivatives as Potential DPP-IV Inhibitors: Pre-ADME Analysis, Toxicity Profile, Computational Analysis, and In Vitro Enzyme Assay

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Molecules, 2023, 28, 1004
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Synthesis and Evaluation of Antidiabetic Potential of Gliptin‐based Hybrid Scaffolds

Shaikh Yahya, Vivek Kumar Gour, Jaiprakash Sangshetti, Prathamesh Deshpande, Mohd Shafeeque, Nisha Sharma, Akram Choudhary and M Shahar Yar

Chemistry & Biodiversity, 2025, 22
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An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus

Gita Chawla, Tathagata Pradhan and Ojasvi Gupta

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Bis(benzimidazol‐2‐yl)amine‐Based DPP‐4 Inhibitors Potentially Suitable for Combating Diabetes and Associated Nervous System Alterations

Katarina Tomović Pavlović, Budimir S. Ilić, Luisa Leitzbach, Kameliya K. Anichina, Denitsa Yancheva, Aleksandra Živković, Anelia Ts Mavrova, Holger Stark and Andrija Šmelcerović

Chemistry & Biodiversity, 2024, 21
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Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α‐glucosidase, α‐amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation

Ahmed Ragab, Mohamed A. Salem, Yousry A. Ammar, Wael M. Aboulthana, Mohamed H. Helal and Moustafa S. Abusaif

Drug Development Research, 2024, 85
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New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies

Dina H. Dawood, Manal M. Sayed, Sally T. K. Tohamy and Eman S. Nossier

ACS Omega, 2023, 8, 39250
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Synthesis of S-alkylated oxadiazole bearing imidazo[2,1-b]thiazole derivatives targeting breast cancer: In vitro cytotoxic evaluation and in vivo radioactive tracing studies

Eman R. Mohammed, Manal Abdel Fattah Ezzat, Emad M. Seif, Basma M. Essa, Hatem A. Abdel-Aziz, Tamer M. Sakr and Hany S. Ibrahim

Bioorganic Chemistry, 2024, 153, 107935
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Discovery of novel hybrids of Morpholino-1,3,5-triazine-pyrimidine as an anti-diabetic agent in High-fat, Low-dose Streptozotocin-induced diabetes in Wistar rats: An in-vitro, in-silico and in-vivo study

Akanksha Gupta, Hans Raj Bhat and Udaya Pratap Singh

Journal of Molecular Structure, 2023, 1294, 136478
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Synthesis and characterization of quinoxaline-based rhenium(I) organometallic compounds: Biological and computational applications

Aelvish D. Padariya, Nirbhay K. Savaliya, Milan P. Dhaduk, Ravi A. Dabhi, Bhupesh S. Bhatt, Vaibhav D. Bhatt and Mohan N. Patel

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Design, Synthesis, and in vitro Evaluation of Derivatives of Quinoxaline-2- One as a Myeloperoxidase Modulator Using in silico Methods

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CBC, 2024, 20
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A novel chitosan-Schiff bases bearing a new quinoxaline moiety as an approach for potent antimicrobial agent: Synthesis, characterization and in vitro assessments

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Silybin loaded Ag‐nanoparticles as a drug delivery system for solid tumor theragnosis: Extraction, radioiodination, and biodistribution study

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Design, discovery, molecular docking, dynamics and in-silico ADME-T evaluation of novel hybrids of 1,3,5-triazine-morpholino-thiazine as an anti-diabetic agent in Wistar rats via inhibition of DPP-4

Akanksha Gupta, Ananya Anurag Anand, Sintu Kumar Samanta, Hans Raj Bhat and Udaya Pratap Singh

Journal of Molecular Structure, 2025, 1345, 141707
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Theophylline Hydrogen Sulfate as a Highly Efficient Catalyst for the Synthesis of Quinoxaline Derivatives: Exploring Potential Antidiabetic Agents Through Molecular Docking

Hemant Kumar Rundla, Shivani Soni, Sunita Teli, Anu Manhas, Prakash C. Jha, Shikha Agarwal and Lokesh Kumar Agarwal

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Insight into Structure Activity Relationship of DPP-4 Inhibitors for Development of Antidiabetic Agents

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Molecules, 2023, 28, 5860
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Computational, in vitro and radiation-based in vivo studies on acetamide quinazolinone derivatives as new proposed purine nucleoside phosphorylase inhibitors for breast cancer

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European Journal of Medicinal Chemistry, 2023, 248, 115087
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Exploring binding mechanisms of omicron spike protein with dolutegravir and etravirine by molecular dynamics simulation, principal component analysis, and free binding energy calculations

Samia A. Elseginy

Journal of Biomolecular Structure and Dynamics, 2025, 43, 2059
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An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024)

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Results in Chemistry, 2025, 13, 101989
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Design, synthesis, radiolabeling, and mechanistic insights of hydrazinyl imidazolones as broad spectrum antitumor agents with potential carbonic anhydrase inhibition: In vitro, in vivo, and in silico studies

Ebtehal M. Husseiny, Marwa T. Sarg, Yasmin S. Sheta, Manal M. Sayed and Fatma G. Abdulrahman

European Journal of Medicinal Chemistry, 2025, 118049
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New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies

Rana M. El-Masry, Basma M. Essa, Adli A. Selim, Soad Z. El-Emam, Khaled O. Mohamed, Tamer M. Sakr, Hanan H. Kadry, Azza T. Taher and Sahar M. Abou-Seri

Pharmaceuticals, 2022, 15, 1476
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Dipeptidyl Peptidase 4 Inhibitors in Type 2 Diabetes Mellitus Management: Pharmacophore Virtual Screening, Molecular Docking, Pharmacokinetic Evaluations, and Conceptual DFT Analysis

Daniela Istrate and Luminita Crisan

Processes, 2023, 11, 3100
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