Propionate alleviates ulcerative colitis by modulating the PI3K/AKT signaling pathway and suppressing NLRP3 inflammasome activation

Yao Shi, Danqing Xin, Haojie Zhang, Shuanglian Wang, Maojun Yang and Chuanyong Liu

Food Funct., 2025, 16, 6925
DOI: 10.1039/D5FO00772K

Lactobacillus rhamnosus Probio-M9 alleviates OVA-sensitized food allergy through modulating gut microbiota and its metabolism

Jialu Shi, Pengfei Dong, Cheng Liu, Yan Xu, Mingzhu Zheng, Lei Cheng, Jin Wang and Vijaya Raghavan

Food Funct., 2023, 14, 10784
DOI: 10.1039/D3FO03321J

Lactobacillus plantarum Alters Gut Microbiota and Metabolites Composition to Improve High Starch Metabolism in Megalobrama amblycephala

Linjie Qian, Siyue Lu, Wenqiang Jiang, Qiaoqiao Mu, Yan Lin, Zhengyan Gu, Yeyang Wu, Xianping Ge and Linghong Miao

Animals, 2025, 15, 583
DOI: 10.3390/ani15040583

Evaluating the anti-inflammatory and antioxidant efficacy of complementary and alternative medicines (CAM) used for management of inflammatory bowel disease: a comprehensive review

Sia Shin, Siqi Chen, Kangzhe Xie, Suehad Abou Duhun and Tamara Ortiz-Cerda

Redox Report, 2025, 30
DOI: 10.1080/13510002.2025.2471737

Protective effect of marine animal hydrolysis-peptides on adjuvant-induced arthritis in mice by gut microbiota and short-chain fatty acids

Zhen Zhang, Shasha Tang, Ziyan Wang, Jiaojiao Han, Jun Zhou, Chenyang Lu, Bin Liu, Xiaoling Sun, Rongxian Yu, Rixin Wang and Xiurong Su

Food Science and Human Wellness, 2025, 14, 9250089
DOI: 10.26599/FSHW.2024.9250089

Lactobacillus acidophilus extracellular vesicles-coated UiO-66-NH2@siRNA nanoparticles for ulcerative colitis targeted gene therapy and gut microbiota modulation

Chenyang Cui, Jiaze Tang, Jie Chen, Beining Zhang, Ruonan Li, Qiang Zhang, Chunjing Qiu, Rongchen Chen, Geng Min, Zhaowei Sun and Haibo Weng

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03376-0

Lactiplantibacillus plantarum OLL2712 Induces Autophagy via MYD88 and Strengthens Tight Junction Integrity to Promote the Barrier Function in Intestinal Epithelial Cells

Yumiko Watanabe-Yasuoka, Ayako Gotou, Shigeomi Shimizu and Toshihiro Sashihara

Nutrients, 2023, 15, 2655
DOI: 10.3390/nu15122655

Lactobacillus acidophilus and its metabolite ursodeoxycholic acid ameliorate ulcerative colitis by promoting Treg differentiation and inhibiting M1 macrophage polarization

Song Deng, Chaoying Pei, Kaiwei Cai, Wenyi Huang, Xiaoyi Xiao, Xingyuan Zhang, Rongyao Liang, Yanlong Chen, Zhiyong Xie, Pei Li and Qiongfeng Liao

Front. Microbiol., 2024, 15
DOI: 10.3389/fmicb.2024.1302998

Effects of Lactiplantibacillus plantarum on oxidative stress, mitophagy, and NLRP3 inflammasome activation in broiler breast meat

Junmeng Yuan, Fan Zhao, Yu Liu, Huawei Liu, Kai Zhang, Xinyu Tian, Yuxin Mu, Jinshan Zhao and Yang Wang

Poultry Science, 2023, 102, 103128
DOI: 10.1016/j.psj.2023.103128

Egg white peptides administration in enhancing pathological immune response and regulating intestinal bacteria abundance: A new strategy for relieving young mice colitis

Huifang Ge, Ting Li, Qi Yang, Yuanhu Tang, Jingbo Liu, Yiding Yu and Ting Zhang

Food Frontiers, 2023, 4, 782
DOI: 10.1002/fft2.213

Links between short-chain fatty acids and osteoarthritis from pathology to clinic via gut-joint axis

Juanjuan Han, Xin Meng, Hui Kong, Xinran Li, Peijie Chen and Xin-an Zhang

Stem Cell Res Ther, 2025, 16
DOI: 10.1186/s13287-025-04386-3

Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice

Yongjia Hu, Xueli Jin, Fei Gao, Ting Lin, Hui Zhu, Xiao Hou, Yu Yin, Shidong Kan and Daijie Chen

Front. Microbiol., 2022, 13
DOI: 10.3389/fmicb.2022.955112

Stronger gut microbiome modulatory effects by postbiotics than probiotics in a mouse colitis model

Tao Zhang, Weiqin Zhang, Cuijiao Feng, Lai-Yu Kwok, Qiuwen He and Zhihong Sun

npj Sci Food, 2022, 6
DOI: 10.1038/s41538-022-00169-9

Therapeutic interventions target the NLRP3 inflammasome in ulcerative colitis: Comprehensive study

Fares E.M Ali, Islam M. Ibrahim, Osama M Ghogar, Esraa K. Abd-alhameed, Hanan S. Althagafy and Emad H.M. Hassanein

World J Gastroenterol, 2023, 29, 1026
DOI: 10.3748/wjg.v29.i6.1026

Preparation of pH-enzyme dual-responsive gel microspheres and their treatment of ulcerative colitis

Yingjie Geng, Yuan Li, Haolong Qi, Jianguo Gao, Yanqing Wu and Xiaoqing Cai

International Journal of Biological Macromolecules, 2025, 306, 141567
DOI: 10.1016/j.ijbiomac.2025.141567

Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections

Qian Xie, Qinhui Li, Hong Fang, Rong Zhang, Huan Tang and Lin Chen

Clinic Rev Allerg Immunol, 2024, 66, 316
DOI: 10.1007/s12016-024-08999-z

New perspectives on key bioactive molecules of lactic acid bacteria: integrating targeted screening, key gene exploration and functional evaluation

Shi Hu, Qi Wang, Jinfeng Wu, Hangjia Zhang, Jiaqi Yin, Lina Ding, Ping Li, Hang Xiao, Qing Gu and Jiarun Han

Critical Reviews in Food Science and Nutrition, 2025, 1
DOI: 10.1080/10408398.2025.2542959

Lactiplantibacillus plantarum-Derived Indole-3-lactic Acid Ameliorates Intestinal Barrier Integrity through the AhR/Nrf2/NF-κB Axis

Arong Wang, Cheng Guan, Tieqi Wang, Guangqing Mu and Yanfeng Tuo

J. Agric. Food Chem., 2024
DOI: 10.1021/acs.jafc.4c01622

Mechanism of Action and Beneficial Effects of Probiotics in Amateur and Professional Athletes

Yousef Nami, Anahita Barghi, Mehdi Shahgolzari, Melika Salehian and Babak Haghshenas

Food Science & Nutrition, 2025, 13
DOI: 10.1002/fsn3.4658

Pogostemon cablin (Blanco) Benth granule revealed a positive effect on improving intestinal barrier function and fecal microbiota in mice with irinotecan-induced intestinal mucositis

Pei Li, Xiaoyi Xiao, Jing Gong, Xingyuan Zhang, Kaiwei Cai, Rongyao Liang, Dawei Wang, Yanlong Chen, Hongying Chen, Zhiyong Xie and Qiongfeng Liao

Arch Microbiol, 2023, 205
DOI: 10.1007/s00203-023-03526-8

Gut microbiota: a novel target for exercise-mediated regulation of NLRP3 inflammasome activation

Jun Chen, Shaohui Jia, Xinxuan Xue, Chenggeng Guo and Kunwei Dong

Front. Microbiol., 2025, 15
DOI: 10.3389/fmicb.2024.1476908

Therapeutic potential of alpha-lipoic acid on mitochondrial dynamics, oxidative/nitrosative stress, and histopathological changes in rat ulcerative colitis model

İrem Taner, Nur Banu Bal, Saadet Özen Akarca Dizakar, Veysel Bay and Mürşide Ayşe Demirel

Inflammopharmacol, 2025
DOI: 10.1007/s10787-025-01918-4

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

Maryam Idrees, Muhammad Imran, Naima Atiq, Rabaab Zahra, Rameesha Abid, Mousa Alreshidi, Tim Roberts, Abdelmuhsin Abdelgadir, Muhammad Khalid Tipu, Arshad Farid, Oluwaseyi Abraham Olawale and Shakira Ghazanfar

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.959941

Protective Effect of Egg Yolk Lipids against Dextran Sulfate Sodium‐Induced Colitis: The Key Role of Gut Microbiota and Short‐Chain Fatty Acids

Nanhai Xiao, Wen He, Shuping Chen, Yao Yao, Na Wu, Mingsheng Xu, Huaying Du, Yan Zhao and Yonggang Tu

Molecular Nutrition Food Res, 2024, 68
DOI: 10.1002/mnfr.202400048

Whey protein and probiotic supplementation ameliorates DSS-induced colitis in mice

Amanda Ascanio, Jaqueline Cristina Galiardo, Eliane Vale da Silva, José Antônio Sampaio Zuanon, Luis Carlos Spolidorio, Letícia de Aquino Penteado, Priscila Marques Firmiano Dalle Piagge, José Fernando Rinaldi de Alvarenga, Alexandra Ivo de Medeiros, Daniel Rodrigues Cardoso and Daniela Cardoso Umbelino Cavallini

International Dairy Journal, 2025, 169, 106336
DOI: 10.1016/j.idairyj.2025.106336

Preclinical evidence of probiotics in ulcerative colitis: a systematic review and network meta-analysis

Wenqin Jin, Huangping Ai, Qingqing Huang, Chuncai Li, Xiang He, Zhao Jin and Yuling Zuo

Front. Pharmacol., 2023, 14
DOI: 10.3389/fphar.2023.1187911

The Mystery of Certain Lactobacillus acidophilus Strains in the Treatment of Gastrointestinal Symptoms of COVID-19: A Review

Belén Bertola, Amparo Cotolí-Crespo, Nadia San Onofre and Jose M. Soriano

Microorganisms, 2025, 13, 944
DOI: 10.3390/microorganisms13040944

Vitamin C supplementation mitigates mild cognitive impairment in mice subjected to D-galactose: Insights into intestinal flora and derived SCFAs

Siju Li, Pengyu Yang, Xiaoyin Cai, Menghui He, Ying He and Feng He

European Journal of Pharmacology, 2025, 1001, 177787
DOI: 10.1016/j.ejphar.2025.177787

A postbiotic exopolysaccharide synergizes with Lactobacillus acidophilus to reduce intestinal inflammation in a mouse model of colitis

Chong Ma, Xiaobin Zheng, Qian Zhang, Stephen James Renaud, Hansheng Yu, Yaning Xu, Yuchun Chen, Jing Gong, Yonghua Cai, Yanjun Hong, Hao Li, Qiongfeng Liao, Ying Guo, Liang Kang and Zhiyong Xie

International Journal of Biological Macromolecules, 2025, 291, 138931
DOI: 10.1016/j.ijbiomac.2024.138931

Probiotics for the treatment of ulcerative colitis: a review of experimental research from 2018 to 2022

Cuilan Huang, Wujuan Hao, Xuyang Wang, Renmin Zhou and Qiong Lin

Front. Microbiol., 2023, 14
DOI: 10.3389/fmicb.2023.1211271

From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders

Duo-Lun Gao, Meng-Ran Lin, Nan Ge, Jin-Tao Guo, Fan Yang and Si-Yu Sun

World J Gastroenterol, 2024, 30, 2934
DOI: 10.3748/wjg.v30.i23.2934

Protective effect of 5,4'-dihydroxy-6,8-dimethoxy7-O-rhamnosylflavone from Indigofera aspalathoides Vahl on lipopolysaccharide-induced intestinal injury in mice

Abdullah M. AlZahrani, Peramaiyan Rajendran, Gamal M. Bekhet, Rajkapoor Balasubramanian, Lalitha Keddal Govindaram, Emad A. Ahmed and Hamza Hanieh

Inflammopharmacol, 2024, 32, 3537
DOI: 10.1007/s10787-024-01530-y

Insights into the intestinal toxicity of foodborne mycotoxins through gut microbiota: A comprehensive review

Haonan Ruan, Ying Huang, Binyang Yue, Yuanyuan Zhang, Jianxin Lv, Kun Miao, Dan Zhang, Jiaoyang Luo and Meihua Yang

Comp Rev Food Sci Food Safe, 2023, 22, 4758
DOI: 10.1111/1541-4337.13242

Role of gut microbes in acute lung injury/acute respiratory distress syndrome

Zixuan Ren, Zhihuan Zheng and Xiujing Feng

Gut Microbes, 2024, 16
DOI: 10.1080/19490976.2024.2440125

Microbial transformation: the role of fermentation in advancing nutritional quality and human health

Babar Iqbal, Khulood Fahad Alabbosh, Abdulkareem Raheem, Inam Ullah, Ali Raza Khan and Muhammad Sohail Memon

Arch Microbiol, 2025, 207
DOI: 10.1007/s00203-025-04435-8

The gut-lung axis in severe acute Pancreatitis-associated lung injury: The protection by the gut microbiota through short-chain fatty acids

Zhengjian Wang, Jin Liu, Fan Li, Yalan Luo, Peng Ge, Yibo Zhang, Haiyun Wen, Qi Yang, Shurong Ma and Hailong Chen

Pharmacological Research, 2022, 182, 106321
DOI: 10.1016/j.phrs.2022.106321

Structural elucidation of a capsular polysaccharide from Bacteroides uniformis and its ameliorative impact on DSS-induced colitis in mice

Chong Ma, Shaobao Zhang, Stephen James Renaud, Qian Zhang, Huiyuan Qi, Haiyun Zhou, Yibao Jin, Hansheng Yu, Yaning Xu, Houshuang Huang, Yanjun Hong, Hao Li, Qiongfeng Liao, Feiqing Ding, Meirong Qin, Ping Wang and Zhiyong Xie

International Journal of Biological Macromolecules, 2024, 279, 135119
DOI: 10.1016/j.ijbiomac.2024.135119

Mitochondria of intestinal epithelial cells in depression: Are they at a crossroads of gut-brain communication?

Yi Wang, Han Lai, Tian Zhang, Jing Wu, Huiling Tang, Xuanwei Liang, Dandan Ren, Jinzhu Huang and Weihong Li

Neuroscience & Biobehavioral Reviews, 2023, 153, 105403
DOI: 10.1016/j.neubiorev.2023.105403

Natural products modulate NLRP3 in ulcerative colitis

Jia-Chen Xue, Shuo Yuan, Xiao-Ting Hou, Huan Meng, Bao-Hong Liu, Wen-Wen Cheng, Ming Zhao, Hong-Ben Li, Xue-Fen Guo, Chang Di, Min-Jie Li and Qing-Gao Zhang

Front. Pharmacol., 2023, 14
DOI: 10.3389/fphar.2023.1265825

Improvement of inflammatory bowel disease by lactic acid bacteria-derived metabolites: a review

Weiling Guo, Bingyong Mao, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Hao Zhang, Wei Chen and Shumao Cui

Critical Reviews in Food Science and Nutrition, 2025, 65, 1261
DOI: 10.1080/10408398.2023.2291188

Targeting gut microbiota and metabolism as the major probiotic mechanism - An evidence-based review

Teng Ma, Xin Shen, Xuan Shi, Hafiz Arbab Sakandar, Keyu Quan, Yalin Li, Hao Jin, Lai-Yu Kwok, Heping Zhang and Zhihong Sun

Trends in Food Science & Technology, 2023, 138, 178
DOI: 10.1016/j.tifs.2023.06.013

Mucoadhesive probiotic-based oral microcarriers with prolonged intestinal retention for inflammatory bowel disease therapy

Kairuo Wang, Qian Chen, Li Ding, Yefei Zhu, Xinyue Wang, Mengting Zhou, Meiqi Chang, Manman Pei, Yuanyuan Zhang, Yang Zhang, Yu Chen and Huanlong Qin

Nano Today, 2023, 50, 101876
DOI: 10.1016/j.nantod.2023.101876

Therapeutic effect of total flavonoids of Sargentodoxa cuneata on ulcerative colitis in mice by correcting gut dysbiosis

Feng Xu, Piao Yu, Hongmei Wu, Xiangpei Wang, Mei Liu, Hongyun Liu, Qian Zeng and Dengli Wu

Arabian Journal of Chemistry, 2024, 17, 105566
DOI: 10.1016/j.arabjc.2023.105566

Polysaccharides extracted from larvae of Lucilia sericata ameliorated ulcerative colitis by regulating the intestinal barrier and gut microbiota

Rong Wang, Bowen Yan, Yourui Yin, Xueyuan Wang, Mei Wu, Tiantian Wen, Yin Qian, Yong Wang, Caoxing Huang and Yongqiang Zhu

International Journal of Biological Macromolecules, 2024, 270, 132441
DOI: 10.1016/j.ijbiomac.2024.132441

Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis

Qian Yang, Peng Zhang, Lu Han, Pengshuang Shi, Zhifang Zhao, Dejun Cui and Kunqiao Hong

Aging, 2024, 16, 3803
DOI: 10.18632/aging.205561

Effects of Probiotics on Gut Microbiota: An Overview

Preethi Chandrasekaran, Sabine Weiskirchen and Ralf Weiskirchen

IJMS, 2024, 25, 6022
DOI: 10.3390/ijms25116022

Large-leaf yellow tea protein derived-peptides alleviated dextran sodium sulfate-induced acute colitis and restored intestinal microbiota balance in C57BL/6 J mice

Huifang Ge, Fengxue Qi, Ziyi Shen, Hongyan Wang, Shangliang Zhu, Simeng Zhou, Zhongwen Xie and Daxiang Li

Food Chemistry, 2024, 456, 139936
DOI: 10.1016/j.foodchem.2024.139936

Lactobacillus acidophilus regulates abnormal serotonin availability in experimental ulcerative colitis

Arzu Hizay, Kubra Dag, Nuriye Oz, Emine Mine Comak-Gocer, Ozlem Ozbey-Unlu, Melike Ucak and Nigar Keles-Celik

Anaerobe, 2023, 80, 102710
DOI: 10.1016/j.anaerobe.2023.102710

Rutin Ameliorates Inflammation and Oxidative Stress in Ulcerative Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway

Xiangdong Zhao, Xiaochao Chen and Chaochi Yue

Cell Biochem Biophys, 2024, 82, 3715
DOI: 10.1007/s12013-024-01459-7