Hydrangenol, an active constituent of Hydrangea serrata (Thunb.) Ser., ameliorates colitis through suppression of macrophage-mediated inflammation in dextran sulfate sodium-treated mice

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Food Funct., 2023, 14, 6957
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Anti-obesity effects of a standardized ethanol extract of Eisenia bicyclis by regulating the AMPK signaling pathway in 3T3-L1 cells and HFD-induced mice

Young-Seo Yoon, Kyung-Sook Chung, Su-Yeon Lee, So-Won Heo, Ye-Rin Kim, Jong Kil Lee, Hyunjae Kim, Soyoon Park, Yu-Kyong Shin and Kyung-Tae Lee

Food Funct., 2024, 15, 6424
DOI: 10.1039/D4FO00759J

Hydrangea serrata extract exerts tumor inhibitory activity against hepatocellular carcinoma HepG2 cells via inducing p27/CDK2-mediated cell cycle arrest and apoptosis

Ye-eun Kim, Jeonghye Hwang and Ki-Young Kim

Asian Pacific Journal of Tropical Biomedicine, 2024, 14, 65
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In vitro and in vivo anti-inflammatory and chondroprotective effects of standardized hot water extract from Hydrangea serrata (Thunb.) Ser. via modulation of NF-κB and MAPK pathways

Huy-Seoung Heo, Min Hyung Cho, Kyung-Sook Chung, Chae-Won Lee, Young-Seo Yoon, Sun-Hee Lee, Hyo-Jin An and Kyung-Tae Lee

Journal of Ethnopharmacology, 2025, 353, 120321
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Protective Effects of a Standardized Water Extract from the Stem of Ipomoea batatas L. Against High-Fat Diet-Induced Obesity

Chae-Won Lee, Ye Seul Yoon, Young-Seo Yoon, Kyung-Sook Chung, Mi-ju Kim, Geonha Park, Minsik Choi, Young-Pyo Jang and Kyung-Tae Lee

Nutrients, 2025, 17, 1643
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In Vitro Evidence for Inhibitory Action of Hydrangea serrata (Thunb.) Ser. Leaf Extract on Urate Crystal-Induced inflammation

Changseon Na, Hyun Jae Kim, Hye Shin Ahn, Yu-Kyong Shin and Sun Hee Lee

Food Suppl Biomater Health, 2021, 1
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Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice

Zhan Zheng, Weilan Gao, Zhenzhou Zhu, Shuyi Li, Xueling Chen, Giancarlo Cravotto, Yong Sui and Lei Zhou

Antioxidants, 2024, 13, 466
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Anti-obesity effect of standardized ethanol extract from the leaves of Adenocaulon himalaicum Edgew. via regulation of adipogenesis and lipid accumulation in 3T3-L1 cells and high-fat diet-induced obese mice

So-Won Heo, Kyung-Sook Chung, Huy-Seoung Heo, Ye-Rin Kim, Chang-Seon Na, Hye-Shin Ahn, Yu-Kyong Shin and Kyung-Tae Lee

Journal of Functional Foods, 2024, 119, 106323
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Lipidomic Assessment of the Inhibitory Effect of Standardized Water Extract of Hydrangea serrata (Thunb.) Ser. Leaves during Adipogenesis

Jae Sik Yu, Hee Ju Kim, Yeo Eun Kim, Hyun Ok Yang, Yu-Kyong Shin, Hyunjae Kim, Soyoon Park and Gakyung Lee

Nutrients, 2024, 16, 1508
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Microbiota-Based Intervention Alleviates High-Fat Diet Consequences Through Host-Microbe Environment Remodeling

Lanlan Yi, Zhipeng Li, Hong Xu, Dejia Shi, Ying Huang, Hongbin Pan, Yanguang Zhao, Hongye Zhao, Minghua Yang, Hongjiang Wei and Sumei Zhao

Nutrients, 2025, 17, 1402
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A Botanical Mixture Consisting of Inula japonica and Potentilla chinensis Relieves Obesity via the AMPK Signaling Pathway in 3T3-L1 Adipocytes and HFD-Fed Obese Mice

Su-Yeon Lee, Kyung-Sook Chung, So-Ri Son, So Young Lee, Dae Sik Jang, Jong-Kil Lee, Hyun-Jae Kim, Chang-Seon Na, Sun-Hee Lee and Kyung-Tae Lee

Nutrients, 2022, 14, 3685
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Phyllodulcin from the hexane fraction of Hydrangea macrophylla inhibits glucose-induced lipid accumulation and reactive oxygen species generation in Caenorhabditis elegans

Myogyeong Cho, Harin Park, Sang Hyun Lee, Myo-Jeong Kim and Miran Jang

Bioscience, Biotechnology, and Biochemistry, 2024, 88, 789
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Yellow leaf green tea modulates the AMPK/ACC/SREBP1c signaling pathway and gut microbiota in high‐fat diet‐induced mice to alleviate obesity

Baoming Tian, Yizhu Pan, Xue Zhou, Yuezhi Jiang, Xiangchun Zhang, Xudong Luo and Kai Yang

J Sci Food Agric, 2024, 104, 5882
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Protective effect of hydrangenol on lipopolysaccharide-induced endotoxemia by suppressing intestinal inflammation

Seo-Yun Jang, Su-Yeon Kim, Hyeon-A Song, Hyeyun Kim, Kyung-Sook Chung, Jong Kil Lee and Kyung-Tae Lee

International Immunopharmacology, 2023, 125, 111083
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Standardized Ethanol Extract of Cassia mimosoides var. nomame Makino Ameliorates Obesity via Regulation of Adipogenesis and Lipogenesis in 3T3-L1 Cells and High-Fat Diet-Induced Obese Mice

So-Won Heo, Kyung-Sook Chung, Young-Seo Yoon, Soo-Yeon Kim, Hye-Shin Ahn, Yu-Kyong Shin, Sun-Hee Lee and Kyung-Tae Lee

Nutrients, 2023, 15, 613
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Etiolated-green tea attenuates colonic barrier dysfunction and inflammation in high-fat diet-induced mice by modulating gut microbiota

Baoming Tian, Yizhu Pan, Xiangchun Zhang, Yuanyuan Wu, Xudong Luo and Kai Yang

Food Research International, 2024, 197, 115192
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Immunomodulatory Effects of a Standardized Botanical Mixture Comprising Angelica gigas Roots and Pueraria lobata Flowers Through the TLR2/6 Pathway in RAW 264.7 Macrophages and Cyclophosphamide-Induced Immunosuppression Mice

Seo-Yun Jang, Hyeon-A Song, Min-Ji Park, Kyung-Sook Chung, Jong Kil Lee, Eun Yeong Jang, Eun Mi Sun, Min Cheol Pyo and Kyung-Tae Lee

Pharmaceuticals, 2025, 18, 336
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Flammulina velutipes mycorrhizae dietary fiber improves lipid metabolism disorders in obese mice through activating AMPK signaling pathway mediated by gut microbiota

Wenliang Wang, Shifa Yang, Shasha Song, Jian Zhang and Fengjuan Jia

Food Bioscience, 2021, 43, 101246
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Effect of Standardized Hydrangea serrata (Thunb.) Ser. Leaves Extract on Body Weight and Body Fat Reduction in Overweight or Obese Humans: A Randomized Double-Blind Placebo-Controlled Study

Hee-Soo Han, Kyung-Sook Chung, Yu-Kyong Shin, Jae-Sik Yu, Seung-Hyun Kang, Sun-Hee Lee and Kyung-Tae Lee

Nutrients, 2022, 14, 208
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Molecular targets of exercise mimetics and their natural activators

Young Jin Jang and Sanguine Byun

BMB Rep, 2021, 54, 581
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Shared signaling pathways and targeted therapy by natural bioactive compounds for obesity and type 2 diabetes

Shuhua Tian, Haizhen Zhao and Haizhao Song

Critical Reviews in Food Science and Nutrition, 2024, 64, 5039
DOI: 10.1080/10408398.2022.2148090

Standardized Hydrangea serrata (Thunb.) Ser. Extract Ameliorates Obesity in db/db Mice

Hee-Soo Han, Kyung-Sook Chung, Yu-Kyoung Shin, Sun Hee Lee and Kyung-Tae Lee

Nutrients, 2021, 13, 3624
DOI: 10.3390/nu13103624