UHT treatment and storage of liquid infant formula affects protein digestion and release of bioactive peptides

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Food Funct., 2022, 13, 344
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Modification of protein structures by altering the whey protein profile and heat treatment affectsin vitrostatic digestion of model infant milk formulas

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Food Funct., 2020, 11, 6933
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Conformational changes of infant formula proteins: effect of whey protein composition and processing step

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International Dairy Journal, 2025, 169, 106312
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Milk Processing Affects Structure, Bioavailability and Immunogenicity of β-lactoglobulin

Kerensa Broersen

Foods, 2020, 9, 874
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Gastric clot formation and digestion of milk proteins in static in vitro infant gastric digestion models representing different ages

Julie Miltenburg, Shanna Bastiaan-Net, Tamara Hoppenbrouwers, Harry Wichers and Kasper Hettinga

Food Chemistry, 2024, 432, 137209
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Baijiu vinasse as a new source of bioactive peptides with antioxidant and anti-inflammatory activity

Lin Peng, Xiaoyong Kong, Zongmin Wang, Aisikaer Ai-lati, Zhongwei Ji and Jian Mao

Food Chemistry, 2021, 339, 128159
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The effect of heat treatment on the lactosylation of milk proteins

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Journal of Dairy Science, 2023, 106, 8321
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Effect of Processing of Whey Protein Ingredient on Maillard Reactions and Protein Structural Changes in Powdered Infant Formula

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J. Agric. Food Chem., 2022, 70, 319
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Effect of glycation degree on the structure and digestion properties of ovalbumin: A study of amino acids and peptides release after in vitro gastrointestinal simulated digestion

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Food Chemistry, 2022, 373, 131331
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Effect of pH and protein composition on proteolysis of goat milk proteins by pepsin and pancreatin

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Alternatives to Cow’s Milk-Based Infant Formulas in the Prevention and Management of Cow’s Milk Allergy

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Foods, 2022, 11, 926
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Cocoa melanoidins reduce the formation of dietary advanced glycation end-products in dairy mimicking system

Hao Zhang, Antonio Dario Troise, Hui Zhang and Vincenzo Fogliano

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In vitro 1H MT and CEST MRI mapping of gastro-intestinal milk protein breakdown

Morwarid Mayar, Paul Smeets, John van Duynhoven and Camilla Terenzi

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α-Lactalbumin: Functional properties and potential health benefits

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Food Bioscience, 2024, 60, 104371
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Propionate Production by Infant Fecal Microbiota Is Inversely Correlated with the Protein Glycation Level of Supplemented Infant Formula Ex Vivo

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The effect of lactose and its isomerization product lactulose on functional and structural properties of glycated casein

Yiru Kong, Qi Dong, Ziyin Yu, Haixia Yan, Ling Liu and Yixiao Shen

Food Research International, 2023, 168, 112683
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Advances, challenges and future directions in the development of in vitro gastrointestinal models used in assessing infant formulas

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Enhanced Uptake of Processed Bovine β‐Lactoglobulin by Antigen Presenting Cells: Identification of Receptors and Implications for Allergenicity

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Comparison of protein digestibility of human milk and infant formula using the INFOGEST method under infant digestion conditions

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Effects of dry heating on the cleavage of casein and whey protein into peptides under simulated infant digestion

Qing Ren, Xuchuan Ma, Sjef Boeren, Paula Keijzer, Harry J. Wichers and Kasper A. Hettinga

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Human milk vs. cow-milk based infant formula proteins: structure, digestion and physiological impacts

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Effect of brewer's spent grain melanoidins on Maillard reaction products during storage of whey protein model systems

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Processing of Dairy Products Can Affect the Digestible Indispensable Amino Acid Score (DIAAS): An In Vivo Study in Bama Minipigs

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Comparison of glycation and glycosylation level between bovine milk-based and goat milk-based infant formula through label-free proteomics techniques

Hongyang Han, Jingjing Pei, Jianhui Feng, Huifang Yao, Binsong Han, Yanmei Hou, Kui Xie, Jinjing Zhong, Lina Zhang, Kasper Hettinga and Peng Zhou

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Comparative Study on Hydrolysis, Physicochemical and Antioxidant Properties in Simulated Digestion System between Cooked Pork and Fish Meat

Yuhan Chen, Hanzhi Jing, Shanbai Xiong, Anne Manyande and Hongying Du

Foods, 2023, 12, 1757
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Gestational Diabetes Mellitus-Induced Changes in Proteomes and Glycated/Glycosylated Proteomes of Human Colostrum

Lina Zhang, Jinyue Zhang, Binsong Han, Chen Chen, Jun Liu, Zhaona Sun, Min Liu and Peng Zhou

J. Agric. Food Chem., 2021, 69, 10749
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Protein glycation compromises the bioavailability of milk protein-derived lysine in vivo in healthy adult males: a double-blind, randomized cross-over trial

Glenn AA van Lieshout, Jorn Trommelen, Jean Nyakayiru, Janneau van Kranenburg, Joan M Senden, Annemie P Gijsen, Lex B Verdijk, Wilbert F Pellikaan, Marjolijn CE Bragt and Luc JC van Loon

The American Journal of Clinical Nutrition, 2025, 121, 804
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Protein Quality in Perspective: A Review of Protein Quality Metrics and Their Applications

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Nutrients, 2022, 14, 947
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Ileal Digestibility of Nitrogen and Amino Acids in Human Milk and an Infant Formula as Determined in Neonatal Minipiglets

Elise Charton, Gwénaële Henry, Armelle Cahu, Yann Le Gouar, Patrice Dahirel, Paul J. Moughan, Carlos A. Montoya, Amandine Bellanger, Didier Dupont, Isabelle Le Huërou-Luron and Amélie Deglaire

The Journal of Nutrition, 2023, 153, 1063
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Standardized methods for testing the quality attributes of plant‐based foods: Milk and cream alternatives

Lutz Grossmann, Amanda J. Kinchla, Alissa Nolden and David Julian McClements

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Functional Characterization of Glycated Peptide Aggregates in Whey Protein Hydrolysates

C. J. Slingerland, M. Laats, H. F. J. Savelkoul, R. J. J. van Neerven and M. Teodorowicz

Food Science & Nutrition, 2025, 13
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Analysis of the Endogenous Peptidomes of Different Infant Formula Types and Human Milk

Michele Wölk, Corinna Gebauer, Ralf Hoffmann and Sanja Milkovska-Stamenova

Foods, 2021, 10, 2579
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Peptide Release after Simulated Infant In Vitro Digestion of Dry Heated Cow’s Milk Protein and Transport of Potentially Immunoreactive Peptides across the Caco-2 Cell Monolayer

Hannah E. Zenker, Harry J. Wichers, Monic M. M. Tomassen, Sjef Boeren, Nicolette W. De Jong and Kasper A. Hettinga

Nutrients, 2020, 12, 2483
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A cross-sectional study on stool- and gastrointestinal-related outcomes of Mexican infants consuming different formulae

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BMC Pediatr, 2023, 23
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Quantification of bovine α-lactalbumin in infant milk formula using LC-MS

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International Dairy Journal, 2021, 113, 104899
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Comprehensive identification and comparative analysis of protein-unbound Amadori products in powdered infant formulas: Integrating untargeted and targeted metabolomics with LC-Q-Orbitrap-MS/MS

Ying Dong, Heng Wang, Guodong Li, Chuyang Wang, Liqiao Han, Zemin Wan, Jun Yan, Qiaoxuan Zhang, Min Zhan, Peifeng Ke, Haibiao Lin, Xinzhong Wu, Xianzhang Huang and Pengwei Zhang

LWT, 2024, 213, 117022
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Glycation of goat milk with different casein-to-whey protein ratios and its effects on simulated infant digestion

Qing Ren, Paula Keijzer, Harry J. Wichers and Kasper A. Hettinga

Food Chemistry, 2024, 450, 139346
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Milk protein coagulation under gastric conditions: A review

Thom Huppertz and Loo Wee Chia

International Dairy Journal, 2021, 113, 104882
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A comprehensive review on infant formula: nutritional and functional constituents, recent trends in processing and its impact on infants’ gut microbiota

Shiva Bakshi, Vinod Kumar Paswan, Satya Prakash Yadav, Basant Kumar Bhinchhar, Sheela Kharkwal, Hency Rose, Prajasattak Kanetkar, Vishal Kumar, Zakarya Ali Saleh Al-Zamani and Durga Shankar Bunkar

Front. Nutr., 2023, 10
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Cooking affects pork proteins in vitro rate of digestion due to different structural and chemical modifications

Bhaskar Mitra, Lars Kristensen, Rene Lametsch and Jorge Ruiz-Carrascal

Meat Science, 2022, 192, 108924
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The Effect of Heat Treatment on the Digestion and Absorption Properties of Protein in Sea Cucumber Body Wall

Min Zhang, Yuxin Liu, Mengling Jin, Deyang Li, Ziye Wang, Pengfei Jiang and Dayong Zhou

Foods, 2023, 12, 2896
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Dairy Foods: A Matrix for Human Health and Precision Nutrition—Effect of processing infant milk formula on protein digestion and gut barrier health (in vitro and preclinical)

Cathal A. Dold, Aylin W. Sahin and Linda Giblin

Journal of Dairy Science, 2025, 108, 3088
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Ovalbumin and its Maillard reaction products ameliorate dextran sulfate sodium-induced colitis by mitigating the imbalance of gut microbiota and metabolites

Qi Yang, Ting Li, Siwen Lyu, Huifang Ge, Meng Yang, Xuanting Liu, Jingbo Liu, Yiding Yu and Ting Zhang

International Journal of Biological Macromolecules, 2022, 222, 715
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Effect of Malondialdehyde on the Digestibility of Beef Myofibrillar Protein: Potential Mechanisms from Structure to Modification Site

Yantao Yin, Lei Zhou, Jiaming Cai, Fan Feng, Lujuan Xing and Wangang Zhang

Foods, 2022, 11, 2176
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The effect of low vs. high temperature dry heating on solubility and digestibility of cow's milk protein

Hannah E. Zenker, Jana Raupbach, Sjef Boeren, Harry J. Wichers and Kasper A. Hettinga

Food Hydrocolloids, 2020, 109, 106098
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Impacts of heat-induced changes on milk protein digestibility: A review

Siqi Li, Aiqian Ye and Harjinder Singh

International Dairy Journal, 2021, 123, 105160
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Calcium bioaccessibility increased during gastrointestinal digestion of α-lactalbumin and β-lactoglobulin

Jing Wang, Kataneh Aalaei, Leif H. Skibsted and Lilia M. Ahrné

Food Research International, 2023, 164, 112415
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Understanding protein digestion in infants and the elderly: Current in vitro digestion models

Seonmin Lee, Kyung Jo, Hyun Gyung Jeong, Yun-Sang Choi, Hae In Yong and Samooel Jung

Critical Reviews in Food Science and Nutrition, 2023, 63, 975
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Milk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial

Glenn AA van Lieshout, Jorn Trommelen, Floris K Hendriks, Jean Nyakayiru, Janneau van Kranenburg, Joan M Senden, Joy PB Goessens, Lex B Verdijk, Marjolijn CE Bragt and Luc JC van Loon

The Journal of Nutrition, 2025, 155, 2215
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Protein Digestibility and Anti-inflammatory Activity of Processed Whey Protein Ingredients for Infant Formula

Yuhui Ye, Yajing Fang, Kasper Engholm-Keller, Mie Rostved Bechshøft, Dereck E.W. Chatterton, Per T. Sangild, Duc Ninh Nguyen, Stine B. Bering and Marianne N. Lund

J. Agric. Food Chem., 2025, 73, 5465
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Detection of intact bovine milk proteins after simulated gastrointestinal infant digestion using UHPLC − HRMS

Sabrina Gensberger-Reigl and Hannah E. Zenker

Food Chemistry, 2025, 465, 142034
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