Protein–protein interaction networks as a new perspective to evaluate distinct functional roles of voltage-dependent anion channel isoforms

Marianna Caterino, Margherita Ruoppolo, Annalisa Mandola, Michele Costanzo, Stefania Orrù and Esther Imperlini

Mol. BioSyst., 2017, 13, 2466
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Voltage-Dependent Anion Selective Channel Isoforms in Yeast: Expression, Structure, and Functions

Maria Carmela Di Rosa, Francesca Guarino, Stefano Conti Nibali, Andrea Magrì and Vito De Pinto

Front. Physiol., 2021, 12
DOI: 10.3389/fphys.2021.675708

Role of cysteines in mammalian VDAC isoforms' function

Vito De Pinto, Simona Reina, Ankit Gupta, Angela Messina and Radhakrishnan Mahalakshmi

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857, 1219
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A Putative Prohibitin-Calcium Nexus in β-Cell Mitochondria and Diabetes

Gaurav Verma, Aparna Dixit, Craig S. Nunemaker and Michaelangela Barbieri

Journal of Diabetes Research, 2020, 2020, 1
DOI: 10.1155/2020/7814628

VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications

Simona Reina, Vanessa Checchetto, Rosaria Saletti, Ankit Gupta, Deepti Chaturvedi, Carlo Guardiani, Francesca Guarino, Mariano Andrea Scorciapino, Andrea Magrì, Salvatore Foti, Matteo Ceccarelli, Angela Anna Messina, Radhakrishnan Mahalakshmi, Ildiko Szabo and Vito De Pinto

Oncotarget, 2016, 7, 2249
DOI: 10.18632/oncotarget.6850

A computational study of ion current modulation in hVDAC3 induced by disulfide bonds

Carlo Guardiani, Loredana Leggio, Mariano Andrea Scorciapino, Vito de Pinto and Matteo Ceccarelli

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016, 1858, 813
DOI: 10.1016/j.bbamem.2016.01.013

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia

Ting Zhu, Bo Liu, Di Wu, Gang Xu and Yang Fan

Front. Cell Dev. Biol., 2021, 9
DOI: 10.3389/fcell.2021.740884

Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability

Andrea Magrì, Ramona Belfiore, Simona Reina, Marianna Flora Tomasello, Maria Carmela Di Rosa, Francesca Guarino, Loredana Leggio, Vito De Pinto and Angela Messina

Sci Rep, 2016, 6
DOI: 10.1038/srep34802

VDAC in cancer

N.M. Mazure

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2017, 1858, 665
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Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells

Teresa Manzo, Boone M. Prentice, Kristin G. Anderson, Ayush Raman, Aislyn Schalck, Gabriela S. Codreanu, Carina B. Nava Lauson, Silvia Tiberti, Andrea Raimondi, Marissa A. Jones, Michelle Reyzer, Breanna M. Bates, Jeffrey M. Spraggins, Nathan H. Patterson, John A. McLean, Kunal Rai, Carlo Tacchetti, Sara Tucci, Jennifer A. Wargo, Simona Rodighiero, Karen Clise-Dwyer, Stacy D. Sherrod, Michael Kim, Nicholas E. Navin, Richard M. Caprioli, Philip D. Greenberg, Giulio Draetta and Luigi Nezi

Journal of Experimental Medicine, 2020, 217
DOI: 10.1084/jem.20191920

Alpha-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease: The Emerging Role of VDAC

Pierpaolo Risiglione, Federica Zinghirino, Maria Carmela Di Rosa, Andrea Magrì and Angela Messina

Biomolecules, 2021, 11, 718
DOI: 10.3390/biom11050718

Cellular Interactome of Mitochondrial Voltage-Dependent Anion Channels: Oligomerization and Channel (Mis)Regulation

Altmash Khan, Gifty Kuriachan and Radhakrishnan Mahalakshmi

ACS Chem. Neurosci., 2021, 12, 3497
DOI: 10.1021/acschemneuro.1c00429

Voltage Dependent Anion Channel 3 (VDAC3) protects mitochondria from oxidative stress

Simona Reina, Stefano Conti Nibali, Marianna Flora Tomasello, Andrea Magrì, Angela Messina and Vito De Pinto

Redox Biology, 2022, 51, 102264
DOI: 10.1016/j.redox.2022.102264

VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease

Fabrizio Cavallaro, Stefano Conti Nibali, Salvatore Antonio Maria Cubisino, Pietro Caruso, Stefania Zimbone, Iolanda Rita Infantino, Simona Reina, Vito De Pinto, Angela Messina, Maria Laura Giuffrida and Andrea Magrì

Aging Cell, 2025, 24
DOI: 10.1111/acel.70069

Voltage-Dependent Anion Selective Channel 3: Unraveling Structural and Functional Features of the Least Known Porin Isoform

Simona Reina and Vanessa Checchetto

Front. Physiol., 2022, 12
DOI: 10.3389/fphys.2021.784867

VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis

Andrea Magrì, Simona Reina and Vito De Pinto

Front. Chem., 2018, 6
DOI: 10.3389/fchem.2018.00108

Targeting mitochondrial ion channels for cancer therapy

Ildiko Szabo, Mario Zoratti and Lucia Biasutto

Redox Biology, 2021, 42, 101846
DOI: 10.1016/j.redox.2020.101846

Enteroviral 2B Interacts with VDAC3 to Regulate Reactive Oxygen Species Generation That Is Essential to Viral Replication

Mei-Ling Cheng, Chien-Hsiang Wu, Kun-Yi Chien, Chien-Hsueh Lai, Guan-Jie Li, Yuan-Yu Liu, Gigin Lin and Hung-Yao Ho

Viruses, 2022, 14, 1717
DOI: 10.3390/v14081717

Specific Post-Translational Modifications of VDAC3 in ALS-SOD1 Model Cells Identified by High-Resolution Mass Spectrometry

Maria Gaetana Giovanna Pittalà, Simona Reina, Stefano Conti Nibali, Annamaria Cucina, Salvatore Antonio Maria Cubisino, Vincenzo Cunsolo, Giuseppe Federico Amodeo, Salvatore Foti, Vito De Pinto, Rosaria Saletti and Angela Messina

IJMS, 2022, 23, 15853
DOI: 10.3390/ijms232415853

VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology

Simona Reina, Francesca Guarino, Andrea Magrì and Vito De Pinto

Front. Oncol., 2016, 6
DOI: 10.3389/fonc.2016.00264

Structural characterization of intra- and intermolecular disulfide bonds in voltage-dependent anion channel 3 (VDAC3) protein from Rattus norvegicus by high-resolution mass spectrometry

Maria Gaetana Giovanna Pittalà, Annamaria Cucina, Stefano Conti-Nibali, Vincenzo Cunsolo, Antonella Di Francesco, Giuseppe Battiato, Simona Reina, Salvatore Foti, Vito De Pinto and Rosaria Saletti

Anal Bioanal Chem, 2025
DOI: 10.1007/s00216-025-06074-w

LSCC SNP variant regulates SOX2 modulation of VDAC3

Jacqueline Chyr, Dongmin Guo and Xiaobo Zhou

Oncotarget, 2018, 9, 22340
DOI: 10.18632/oncotarget.24918

VDACs Post-Translational Modifications Discovery by Mass Spectrometry: Impact on Their Hub Function

Maria Gaetana Giovanna Pittalà, Stefano Conti Nibali, Simona Reina, Vincenzo Cunsolo, Antonella Di Francesco, Vito De Pinto, Angela Messina, Salvatore Foti and Rosaria Saletti

IJMS, 2021, 22, 12833
DOI: 10.3390/ijms222312833

NRF-1 and HIF-1α contribute to modulation of human VDAC1 gene promoter during starvation and hypoxia in HeLa cells

Francesca Guarino, Federica Zinghirino, Lia Mela, Xena Giada Pappalardo, François Ichas, Vito De Pinto and Angela Messina

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2020, 1861, 148289
DOI: 10.1016/j.bbabio.2020.148289