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New insights into mammalian signaling pathways using microfluidic pulsatile inputs and mathematical modeling
M. Sumit, S. Takayama and J. J. Linderman
Integr. Biol., 2017, 9, 6
DOI: 10.1039/C6IB00178E

Kinetic analysis of sequential metabolism of triazolam and its extrapolation to humans using an entero-hepatic two-organ microphysiological system
Hiroshi Arakawa, Shinji Sugiura, Takumi Kawanishi, Kazumi Shin, Hiroko Toyoda, Taku Satoh, Yasuyuki Sakai, Toshiyuki Kanamori and Yukio Kato
Lab Chip, 2020, 20, 537
DOI: 10.1039/C9LC00884E

In vitro functional models for human liver diseases and drug screening: beyond animal testing
Alessia Paradiso, Marina Volpi, Chiara Rinoldi, Nehar Celikkin, Nicola Contessi Negrini, Muge Bilgen, Giorgio Dallera, Filippo Pierini, Marco Costantini, Wojciech Święszkowski and Silvia Farè
Biomater. Sci., 2023, 11, 2988
DOI: 10.1039/D1BM01872H

A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control
J. R. Coppeta, M. J. Mescher, B. C. Isenberg, A. J. Spencer, E. S. Kim, A. R. Lever, T. J. Mulhern, R. Prantil-Baun, J. C. Comolli and J. T. Borenstein
Lab Chip, 2017, 17, 134
DOI: 10.1039/C6LC01236A

Multi-layered, membrane-integrated microfluidics based on replica molding of a thiol–ene epoxy thermoset for organ-on-a-chip applications
Drago Sticker, Mario Rothbauer, Sarah Lechner, Marie-Therese Hehenberger and Peter Ertl
Lab Chip, 2015, 15, 4542
DOI: 10.1039/C5LC01028D

3D-templated, fully automated microfluidic input/output multiplexer for endocrine tissue culture and secretion sampling
Xiangpeng Li, Jessica C. Brooks, Juan Hu, Katarena I. Ford and Christopher J. Easley
Lab Chip, 2017, 17, 341
DOI: 10.1039/C6LC01201A

A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node
Sophie R. Cook, Alexander G. Ball, Anwaruddin Mohammad and Rebecca R. Pompano
Lab Chip, 2025, 25, 155
DOI: 10.1039/D4LC00489B

Research highlights
Šeila Selimović, Mehmet R. Dokmeci and Ali Khademhosseini
Lab Chip, 2014, 14, 264
DOI: 10.1039/C3LC90126B

Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling
Hasan Erbil Abaci and Michael L. Shuler
Integr. Biol., 2015, 7, 383
DOI: 10.1039/C4IB00292J

Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution
Juan Hu, Xiangpeng Li, Robert L. Judd and Christopher J. Easley
Lab Chip, 2020, 20, 1503
DOI: 10.1039/D0LC00103A

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Ilka Maschmeyer, Alexandra K. Lorenz, Katharina Schimek, Tobias Hasenberg, Anja P. Ramme, Juliane Hübner, Marcus Lindner, Christopher Drewell, Sophie Bauer, Alexander Thomas, Naomia Sisoli Sambo, Frank Sonntag, Roland Lauster and Uwe Marx
Lab Chip, 2015, 15, 2688
DOI: 10.1039/C5LC00392J

Fattening chips: hypertrophy, feeding, and fasting of human white adipocytesin vitro
Benjamin D. Pope, Curtis R. Warren, Madeleine O. Dahl, Christina V. Pizza, Douglas E. Henze, Nina R. Sinatra, Grant M. Gonzalez, Huibin Chang, Qihan Liu, Aaron L. Glieberman, John P. Ferrier, Chad A. Cowan and Kevin Kit Parker
Lab Chip, 2020, 20, 4152
DOI: 10.1039/D0LC00508H

A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform
T. Satoh, S. Sugiura, K. Shin, R. Onuki-Nagasaki, S. Ishida, K. Kikuchi, M. Kakiki and T. Kanamori
Lab Chip, 2018, 18, 115
DOI: 10.1039/C7LC00952F

A similarity scaling approach for organ-on-chip devices
James J. Feng and Sarah Hedtrich
Lab Chip, 2022, 22, 3663
DOI: 10.1039/D2LC00641C

Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS)
Christian Maass, Cynthia L. Stokes, Linda G. Griffith and Murat Cirit
Integr. Biol., 2017, 9, 290
DOI: 10.1039/C6IB00243A

Engineering cell heterogeneity into organs-on-a-chip
David R. Mertz, Tasdiq Ahmed and Shuichi Takayama
Lab Chip, 2018, 18, 2378
DOI: 10.1039/C8LC00413G

Approaching the in vitro clinical trial: engineering organs on chips
A. K. Capulli, K. Tian, N. Mehandru, A. Bukhta, S. F. Choudhury, M. Suchyta and K. K. Parker
Lab Chip, 2014, 14, 3181
DOI: 10.1039/C4LC00276H

Organ-on-a-chip devices advance to market
Boyang Zhang and Milica Radisic
Lab Chip, 2017, 17, 2395
DOI: 10.1039/C6LC01554A

A 96-well microplate bioreactor platform supporting individual dual perfusion and high-throughput assessment of simple or biofabricated 3D tissue models
J. Parrish, K. S. Lim, K. Baer, G. J. Hooper and T. B. F. Woodfield
Lab Chip, 2018, 18, 2757
DOI: 10.1039/C8LC00485D

A microfluidic device for evaluating the dynamics of the metabolism-dependent antioxidant activity of nutrients
Jungwoo Lee, Jong-ryul Choi, Sang Keun Ha, Inwook Choi, Seung Hwan Lee, Donghyun Kim, Nakwon Choi and Jong Hwan Sung
Lab Chip, 2014, 14, 2948
DOI: 10.1039/C4LC00332B

Physiome‐on‐a‐Chip: The Challenge of “Scaling” in Design, Operation, and Translation of Microphysiological Systems
CL Stokes, M Cirit and DA Lauffenburger
CPT Pharmacom & Syst Pharma, 2015, 4, 559
DOI: 10.1002/psp4.12042

Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics
Tanvi Shroff, Kehinde Aina, Christian Maass, Madalena Cipriano, Joeri Lambrecht, Frank Tacke, Alexander Mosig and Peter Loskill
Open Biol., 2022, 12
DOI: 10.1098/rsob.210333

Organs-on-a-chip: a new tool for drug discovery
Alessandro Polini, Ljupcho Prodanov, Nupura S Bhise, Vijayan Manoharan, Mehmet R Dokmeci and Ali Khademhosseini
Expert Opinion on Drug Discovery, 2014, 9, 335
DOI: 10.1517/17460441.2014.886562

Towards an Insulin Resistant Adipose Model on a Chip
Nida Tanataweethum, Franklin Zhong, Allyson Trang, Chaeeun Lee, Ronald N. Cohen and Abhinav Bhushan
Cel. Mol. Bioeng., 2021, 14, 89
DOI: 10.1007/s12195-020-00636-x

Microtechnology-Based Multi-Organ Models
Seung Lee and Jong Sung
Bioengineering, 2017, 4, 46
DOI: 10.3390/bioengineering4020046

Stem-cell based organ-on-a-chip models for diabetes research
Julia Rogal, Aline Zbinden, Katja Schenke-Layland and Peter Loskill
Advanced Drug Delivery Reviews, 2019, 140, 101
DOI: 10.1016/j.addr.2018.10.010

Allometric Scaling of physiologically-relevant organoids
Chiara Magliaro, Andrea Rinaldo and Arti Ahluwalia
Sci Rep, 2019, 9
DOI: 10.1038/s41598-019-48347-2

Eligibility of patients with renal impairment for Phase I trials: Time for a rethink?
Laeeq Malik, Alex Mejia and Steven Weitman
European Journal of Cancer, 2014, 50, 2893
DOI: 10.1016/j.ejca.2014.09.001

Tissue-in-a-Tube: three-dimensional in vitro tissue constructs with integrated multimodal environmental stimulation
A. Shahin-Shamsabadi and P.R. Selvaganapathy
Materials Today Bio, 2020, 7, 100070
DOI: 10.1016/j.mtbio.2020.100070

Organ-on-a-chip and the kidney
Sejoong Kim and Shuichi Takayama
Kidney Research and Clinical Practice, 2015, 34, 165
DOI: 10.1016/j.krcp.2015.08.001

Joint-on-chip platforms: entering a new era of in vitro models for arthritis
Carlo Alberto Paggi, Liliana Moreira Teixeira, Séverine Le Gac and Marcel Karperien
Nat Rev Rheumatol, 2022, 18, 217
DOI: 10.1038/s41584-021-00736-6

Application of chemical reaction engineering principles to “body‐on‐a‐chip” systems
Jong Hwan Sung, Ying I. Wang, Jung Hun Kim, Jong Min Lee and Michael L. Shuler
AIChE Journal, 2018, 64, 4351
DOI: 10.1002/aic.16448

Perspective: The promise of multi-cellular engineered living systems
Roger D. Kamm, Rashid Bashir, Natasha Arora, Roy D. Dar, Martha U. Gillette, Linda G. Griffith, Melissa L. Kemp, Kathy Kinlaw, Michael Levin, Adam C. Martin, Todd C. McDevitt, Robert M. Nerem, Mark J. Powers, Taher A. Saif, James Sharpe, Shuichi Takayama, Shoji Takeuchi, Ron Weiss, Kaiming Ye, Hannah G. Yevick and Muhammad H. Zaman
APL Bioengineering, 2018, 2
DOI: 10.1063/1.5038337

Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids
Camille Cassel de Camps, Saba Aslani, Nicholas Stylianesis, Harris Nami, Nguyen-Vi Mohamed, Thomas M. Durcan and Christopher Moraes
ACS Appl. Bio Mater., 2022, 5, 214
DOI: 10.1021/acsabm.1c01047

Circadian hormone control in a human-on-a-chip:In vitrobiology’s ignored component?
Kevin J. Cyr, Omero M. Avaldi and John P. Wikswo
Exp Biol Med (Maywood), 2017, 242, 1714
DOI: 10.1177/1535370217732766

Microtechnology‐based organ systems and whole‐body models for drug screening
Seung Hwan Lee, Sang Keun Ha, Inwook Choi, Nakwon Choi, Tai Hyun Park and Jong Hwan Sung
Biotechnology Journal, 2016, 11, 746
DOI: 10.1002/biot.201500551

Biomimetic microsystems for cardiovascular studies
Shelby C. Inbody, Bridgett E. Sinquefield, Joshua P. Lewis and Renita E. Horton
American Journal of Physiology-Cell Physiology, 2021, 320, C850
DOI: 10.1152/ajpcell.00026.2020

Scaling of joint mass and metabolism fluctuations in in silico cell-laden spheroids
Ermes Botte, Francesco Biagini, Chiara Magliaro, Andrea Rinaldo, Amos Maritan and Arti Ahluwalia
Proc. Natl. Acad. Sci. U.S.A., 2021, 118
DOI: 10.1073/pnas.2025211118

Microfluidic Gut-liver chip for reproducing the first pass metabolism
Aerim Choe, Sang Keun Ha, Inwook Choi, Nakwon Choi and Jong Hwan Sung
Biomed Microdevices, 2017, 19
DOI: 10.1007/s10544-016-0143-2

Fat-On-A-Chip Models for Research and Discovery in Obesity and Its Metabolic Comorbidities
Michelle McCarthy, Theodore Brown, Andrea Alarcon, Christopher Williams, Xiying Wu, Rosalyn D. Abbott, Jeffrey Gimble and Trivia Frazier
Tissue Engineering Part B: Reviews, 2020, 26, 586
DOI: 10.1089/ten.teb.2019.0261

Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure
Jong Hwan Sung, Balaji Srinivasan, Mandy Brigitte Esch, William T McLamb, Catia Bernabini, Michael L Shuler and James J Hickman
Exp Biol Med (Maywood), 2014, 239, 1225
DOI: 10.1177/1535370214529397

Recent Advances in Body-on-a-Chip Systems
Jong Hwan Sung, Ying I. Wang, Narasimhan Narasimhan Sriram, Max Jackson, Christopher Long, James J. Hickman and Michael L. Shuler
Anal. Chem., 2019, 91, 330
DOI: 10.1021/acs.analchem.8b05293

Integrating Organs-on-Chips: Multiplexing, Scaling, Vascularization, and Innervation
DoYeun Park, Jaeseo Lee, Justin J. Chung, Youngmee Jung and Soo Hyun Kim
Trends in Biotechnology, 2020, 38, 99
DOI: 10.1016/j.tibtech.2019.06.006

Microfluidic Organ‐on‐a‐Chip Technology for Advancement of Drug Development and Toxicology
Jeremy D. Caplin, Norma G. Granados, Myra R. James, Reza Montazami and Nastaran Hashemi
Adv Healthcare Materials, 2015, 4, 1426
DOI: 10.1002/adhm.201500040

Next generation human skin constructs as advanced tools for drug development
HE Abaci, Zongyou Guo, Yanne Doucet, Joanna Jacków and Angela Christiano
Exp Biol Med (Maywood), 2017, 242, 1657
DOI: 10.1177/1535370217712690

New Frontiers for Biofabrication and Bioreactor Design in Microphysiological System Development
Jonathon Parrish, Khoon Lim, Boyang Zhang, Milica Radisic and Tim B.F. Woodfield
Trends in Biotechnology, 2019, 37, 1327
DOI: 10.1016/j.tibtech.2019.04.009

Multiorgan-on-a-Chip: A Systemic Approach To Model and Decipher Inter-Organ Communication
Nathalie Picollet-D’hahan, Agnieszka Zuchowska, Iris Lemeunier and Séverine Le Gac
Trends in Biotechnology, 2021, 39, 788
DOI: 10.1016/j.tibtech.2020.11.014

Mammalian Cell-Growth Monitoring Based on an Impedimetric Sensor and Image Processing within a Microfluidic Platform
Ivana Podunavac, Teodora Knežić, Mila Djisalov, Nejra Omerovic, Marko Radovic, Ljiljana Janjušević, Dimitrije Stefanovic, Marko Panic, Ivana Gadjanski and Vasa Radonic
Sensors, 2023, 23, 3748
DOI: 10.3390/s23073748

Strategies for using mathematical modeling approaches to design and interpret multi-organ microphysiological systems (MPS)
Jong Hwan Sung, Ying Wang and Michael L. Shuler
APL Bioengineering, 2019, 3
DOI: 10.1063/1.5097675

Engineered In Vitro Disease Models
Kambez H. Benam, Stephanie Dauth, Bryan Hassell, Anna Herland, Abhishek Jain, Kyung-Jin Jang, Katia Karalis, Hyun Jung Kim, Luke MacQueen, Roza Mahmoodian, Samira Musah, Yu-suke Torisawa, Andries D. van der Meer, Remi Villenave, Moran Yadid, Kevin K. Parker and Donald E. Ingber
Annu. Rev. Pathol. Mech. Dis., 2015, 10, 195
DOI: 10.1146/annurev-pathol-012414-040418

Microfluidics chip design analysis and control
Ismet Unalli, Sezgin Ersoy and Ishak Ertugrul
J. mechatron., artif. intell., eng., 2020, 1, 2
DOI: 10.21595/jmai.2020.21470

Integration Concepts for Multi-Organ Chips: How to Maintain Flexibility?!
Julia Rogal, Christopher Probst and Peter Loskill
Future Sci. OA, 2017, 3
DOI: 10.4155/fsoa-2016-0092

Multi-organ-on-a-chip for pharmacokinetics and toxicokinetic study of drugs
Jong Hwan Sung
Expert Opinion on Drug Metabolism & Toxicology, 2021, 17, 969
DOI: 10.1080/17425255.2021.1908996

Allometric scaling in-vitro
Arti Ahluwalia
Sci Rep, 2017, 7
DOI: 10.1038/srep42113

3D gut-liver chip with a PK model for prediction of first-pass metabolism
Dong Wook Lee, Sang Keun Ha, Inwook Choi and Jong Hwan Sung
Biomed Microdevices, 2017, 19
DOI: 10.1007/s10544-017-0242-8

Sizing it up: The mechanical feedback hypothesis of organ growth regulation
Amy Buchmann, Mark Alber and Jeremiah J. Zartman
Seminars in Cell & Developmental Biology, 2014, 35, 73
DOI: 10.1016/j.semcdb.2014.06.018

Self-contained, low-cost Body-on-a-Chip systems for drug development
Ying I Wang, Carlota Oleaga, Christopher J Long, Mandy B Esch, Christopher W McAleer, Paula G Miller, James J Hickman and Michael L Shuler
Exp Biol Med (Maywood), 2017, 242, 1701
DOI: 10.1177/1535370217694101

EmergingIn VitroLiver Technologies for Drug Metabolism and Inter-Organ Interactions
Shyam Sundhar Bale, Laura Moore, Martin Yarmush and Rohit Jindal
Tissue Engineering Part B: Reviews, 2016, 22, 383
DOI: 10.1089/ten.teb.2016.0031

Bringing 3D tumor models to the clinic – predictive value for personalized medicine
Kathrin Halfter and Barbara Mayer
Biotechnology Journal, 2017, 12
DOI: 10.1002/biot.201600295

Optical glucose sensor for microfluidic cell culture systems
Stefanie Fuchs, Veronika Rieger, Anders Ø. Tjell, Sarah Spitz, Konstanze Brandauer, Roland Schaller-Ammann, Jürgen Feiel, Peter Ertl, Ingo Klimant and Torsten Mayr
Biosensors and Bioelectronics, 2023, 237, 115491
DOI: 10.1016/j.bios.2023.115491

Advances and Challenges in Recapitulating Human Pulmonary Systems: At the Cusp of Biology and Materials
Piyush Bajaj, Jennifer F. Harris, Jen-Huang Huang, Pulak Nath and Rashi Iyer
ACS Biomater. Sci. Eng., 2016, 2, 473
DOI: 10.1021/acsbiomaterials.5b00480

In vitromicrofluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
Altug Ozcelikkale, Hye‐ran Moon, Michael Linnes and Bumsoo Han
WIREs Nanomed Nanobiotechnol, 2017, 9
DOI: 10.1002/wnan.1460

Mimicking the Kidney: A Key Role in Organ-on-Chip Development
Roberto Paoli and Josep Samitier
Micromachines, 2016, 7, 126
DOI: 10.3390/mi7070126

Membrane‐Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions
Richard H. Barnes, Takeshi Akama, Miina K. Öhman, Moon‐Sook Woo, Julian Bahr, Stephen J. Weiss, Daniel T. Eitzman and Tae‐Hwa Chun
JAHA, 2017, 6
DOI: 10.1161/JAHA.116.003693

Thinking in 3 dimensions: philosophies of the microenvironment in organoids and organs-on-chip
Silvia Caianiello, Marta Bertolaso and Guglielmo Militello
HPLS, 2023, 45
DOI: 10.1007/s40656-023-00560-z

2021 update on thyroid-associated ophthalmopathy
E. J. Neag and T. J. Smith
J Endocrinol Invest, 2022, 45, 235
DOI: 10.1007/s40618-021-01663-9

In-plane microvortices micromixer-based AC electrothermal for testing drug induced death of tumor cells
Qi Lang, Yukun Ren, Divia Hobson, Ye Tao, Likai Hou, Yankai Jia, Qingming Hu, Jiangwei Liu, Xin Zhao and Hongyuan Jiang
Biomicrofluidics, 2016, 10
DOI: 10.1063/1.4967455

A pumpless multi‐organ‐on‐a‐chip (MOC) combined with a pharmacokinetic–pharmacodynamic (PK–PD) model
Hyuna Lee, Dae Shik Kim, Sang Keun Ha, Inwook Choi, Jong Min Lee and Jong Hwan Sung
Biotech & Bioengineering, 2017, 114, 432
DOI: 10.1002/bit.26087

A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices
Seyed Ali Mousavi Shaegh, Fabio De Ferrari, Yu Shrike Zhang, Mahboubeh Nabavinia, Niema Binth Mohammad, John Ryan, Adel Pourmand, Eleanor Laukaitis, Ramin Banan Sadeghian, Akhtar Nadhman, Su Ryon Shin, Amir Sanati Nezhad, Ali Khademhosseini and Mehmet Remzi Dokmeci
Biomicrofluidics, 2016, 10
DOI: 10.1063/1.4955155

Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Guoyou Huang, Fei Li, Xin Zhao, Yufei Ma, Yuhui Li, Min Lin, Guorui Jin, Tian Jian Lu, Guy M. Genin and Feng Xu
Chem. Rev., 2017, 117, 12764
DOI: 10.1021/acs.chemrev.7b00094

Tissue chips as headway model and incitement technology
Prerna Suchitan Modi, Abhishek Singh, Awyang Chaturvedi, Shailly Agarwal, Raghav Dutta, Ranu Nayak and Alok Kumar Singh
Synthetic and Systems Biotechnology, 2025, 10, 86
DOI: 10.1016/j.synbio.2024.08.007

Construction of pancreas–muscle–liver microphysiological system (MPS) for reproducing glucose metabolism
Dong Wook Lee, Seung Hwan Lee, Nakwon Choi and Jong Hwan Sung
Biotech & Bioengineering, 2019, 116, 3433
DOI: 10.1002/bit.27151

Microphysiological Systems: Design, Fabrication, and Applications
Kai Wang, Kun Man, Jiafeng Liu, Yang Liu, Qi Chen, Yong Zhou and Yong Yang
ACS Biomater. Sci. Eng., 2020, 6, 3231
DOI: 10.1021/acsbiomaterials.9b01667

Organ-on-a-chip platforms for studying drug delivery systems
Nupura S. Bhise, João Ribas, Vijayan Manoharan, Yu Shrike Zhang, Alessandro Polini, Solange Massa, Mehmet R. Dokmeci and Ali Khademhosseini
Journal of Controlled Release, 2014, 190, 82
DOI: 10.1016/j.jconrel.2014.05.004

Microfabricated Physiological Models for In Vitro Drug Screening Applications
Giovanni Ugolini, Daniela Cruz-Moreira, Roberta Visone, Alberto Redaelli and Marco Rasponi
Micromachines, 2016, 7, 233
DOI: 10.3390/mi7120233

High-Content Assessment of Cardiac Function Using Heart-on-a-Chip Devices as Drug Screening Model
Genevieve Conant, Benjamin Fook Lun Lai, Rick Xing Ze Lu, Anastasia Korolj, Erika Yan Wang and Milica Radisic
Stem Cell Rev and Rep, 2017, 13, 335
DOI: 10.1007/s12015-017-9736-2

Organ‐on‐a‐Chip Systems for Women's Health Applications
Janna Nawroth, Julia Rogal, Martin Weiss, Sara Y. Brucker and Peter Loskill
Adv Healthcare Materials, 2018, 7
DOI: 10.1002/adhm.201700550

Lab-on-a-chip workshop activities for secondary school students
Mohammad M. N. Esfahani, Mark D. Tarn, Tahmina A. Choudhury, Laura C. Hewitt, Ashley J. Mayo, Theodore A. Rubin, Mathew R. Waller, Martin G. Christensen, Amy Dawson and Nicole Pamme
Biomicrofluidics, 2016, 10
DOI: 10.1063/1.4940884

3D engineered tissue models for studying human-specific infectious viral diseases
Kyeong Seob Hwang, Eun U Seo, Nakwon Choi, Jongbaeg Kim and Hong Nam Kim
Bioactive Materials, 2023, 21, 576
DOI: 10.1016/j.bioactmat.2022.09.010

A liver-on-a-chip platform with bioprinted hepatic spheroids
Nupura S Bhise, Vijayan Manoharan, Solange Massa, Ali Tamayol, Masoumeh Ghaderi, Mario Miscuglio, Qi Lang, Yu Shrike Zhang, Su Ryon Shin, Giovanni Calzone, Nasim Annabi, Thomas D Shupe, Colin E Bishop, Anthony Atala, Mehmet R Dokmeci and Ali Khademhosseini
Biofabrication, 2016, 8, 014101
DOI: 10.1088/1758-5090/8/1/014101

Microfluidic trends in drug screening and drug delivery
Jianguo Feng, Jiri Neuzil, Andreas Manz, Ciprian Iliescu and Pavel Neuzil
TrAC Trends in Analytical Chemistry, 2023, 158, 116821
DOI: 10.1016/j.trac.2022.116821

Human-Derived Organ-on-a-Chip for Personalized Drug Development
Yasamin A. Jodat , Min G. Kang, Kiavash Kiaee, Gyeong J. Kim, Angel F.H. Martinez, Aliza Rosenkranz, Hojae Bae and Su R. Shin
CPD, 2019, 24, 5471
DOI: 10.2174/1381612825666190308150055

Microphysiological systems: What it takes for community adoption
Passley Hargrove-Grimes, Lucie A Low and Danilo A Tagle
Exp Biol Med (Maywood), 2021, 246, 1435
DOI: 10.1177/15353702211008872

Advances in organ-on-a-chip engineering
Boyang Zhang, Anastasia Korolj, Benjamin Fook Lun Lai and Milica Radisic
Nat Rev Mater, 2018, 3, 257
DOI: 10.1038/s41578-018-0034-7

Microfluidic systems for studying dynamic function of adipocytes and adipose tissue
Xiangpeng Li and Christopher J. Easley
Anal Bioanal Chem, 2018, 410, 791
DOI: 10.1007/s00216-017-0741-8

Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips
Rachelle Prantil-Baun, Richard Novak, Debarun Das, Mahadevabharath R. Somayaji, Andrzej Przekwas and Donald E. Ingber
Annu. Rev. Pharmacol. Toxicol., 2018, 58, 37
DOI: 10.1146/annurev-pharmtox-010716-104748

Studying Adipose Tissue in the Breast Tumor Microenvironment In Vitro: Progress and Opportunities
David Mertz, Jason Sentosa, Gary Luker and Shuichi Takayama
Tissue Eng Regen Med, 2020, 17, 773
DOI: 10.1007/s13770-020-00299-9

The relevance and potential roles of microphysiological systems in biology and medicine
John P Wikswo
Exp Biol Med (Maywood), 2014, 239, 1061
DOI: 10.1177/1535370214542068

Targeted Cancer Therapy‐on‐A‐Chip
Heba Abed, Remya Radha, Shabana Anjum, Vinod Paul, Nour AlSawaftah, William G. Pitt, Nureddin Ashammakhi and Ghaleb A. Husseini
Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202400833

High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches
Huagui Zhang, Richard D Whalley, Ana Marina Ferreira and Kenneth Dalgarno
Prog. Biomed. Eng., 2020, 2, 022001
DOI: 10.1088/2516-1091/ab7cc4

Patient‐Specific Organoid and Organ‐on‐a‐Chip: 3D Cell‐Culture Meets 3D Printing and Numerical Simulation
Fuyin Zheng, Yuminghao Xiao, Hui Liu, Yubo Fan and Ming Dao
Advanced Biology, 2021, 5
DOI: 10.1002/adbi.202000024

Manufacturing of Microfluidic Sensors Utilizing 3D Printing Technologies: A Production System
Danial Khorsandi, Mehrab Nodehi, Tayyab Waqar, Majid Shabani, Behnam Kamare, Ehsan Nazarzadeh Zare, Sezgin Ersoy, Mohsen Annabestani, Mehmet Fatih Çelebi, Abdullah Kafadenk and Jianbo Yin
Journal of Nanomaterials, 2021, 2021, 1
DOI: 10.1155/2021/5537074

Organ‐on‐a‐Chip Technology for Reproducing Multiorgan Physiology
Seung Hwan Lee and Jong Hwan Sung
Adv Healthcare Materials, 2018, 7
DOI: 10.1002/adhm.201700419

Have microfluidics delivered for drug discovery?
Arvind Chandrasekaran, Marwan Abduljawad and Christopher Moraes
Expert Opinion on Drug Discovery, 2016, 11, 745
DOI: 10.1080/17460441.2016.1193485

Pharmacokinetic Analysis of Epithelial/Endothelial Cell Barriers in Microfluidic Bilayer Devices with an Air–Liquid Interface
Timothy S. Frost, Linan Jiang and Yitshak Zohar
Micromachines, 2020, 11, 536
DOI: 10.3390/mi11050536

The feasible application of microfluidic tissue/organ-on-a-chip as an impersonator of oral tissues and organs: a direction for future research
Nima Farshidfar, Sahar Assar, Mohammad Amin Amiri, Sarina Sahmeddini, Shahram Hamedani, Moein Zarei and Lobat Tayebi
Bio-des. Manuf., 2023, 6, 478
DOI: 10.1007/s42242-023-00235-5

HIF2A–LOX Pathway Promotes Fibrotic Tissue Remodeling in Thyroid-Associated Orbitopathy
Fumihito Hikage, Stephen Atkins, Alon Kahana, Terry J Smith and Tae-Hwa Chun
Endocrinology, 2019, 160, 20
DOI: 10.1210/en.2018-00272

Allometric Scaling and Cell Ratios in Multi-Organ in vitro Models of Human Metabolism
Nadia Ucciferri, Tommaso Sbrana and Arti Ahluwalia
Front. Bioeng. Biotechnol., 2014, 2
DOI: 10.3389/fbioe.2014.00074

Microfluidic-Based Multi-Organ Platforms for Drug Discovery
Ahmad Rezaei Kolahchi, Nima Khadem Mohtaram, Hassan Pezeshgi Modarres, Mohammad Mohammadi, Armin Geraili, Parya Jafari, Mohsen Akbari and Amir Sanati-Nezhad
Micromachines, 2016, 7, 162
DOI: 10.3390/mi7090162

Liver-on-chips for drug discovery and development
Viraj Mehta, Guruswamy Karnam and Vamsi Madgula
Materials Today Bio, 2024, 27, 101143
DOI: 10.1016/j.mtbio.2024.101143

Mimicking the Human Physiology with Microphysiological Systems (MPS)
Jong Hwan Sung, Jamin Koo and Michael L. Shuler
BioChip J, 2019, 13, 115
DOI: 10.1007/s13206-019-3201-z

Building an experimental model of the human body with non-physiological parameters
Joseph M. Labuz, Christopher Moraes, David R. Mertz, Brendan M. Leung and Shuichi Takayama
Technology, 2017, 05, 42
DOI: 10.1142/S2339547817500029

Predictive Design and Analysis of Drug Transport by Multiscale Computational Models Under Uncertainty
Ali Aykut Akalın, Barış Dedekargınoğlu, Sae Rome Choi, Bumsoo Han and Altug Ozcelikkale
Pharm Res, 2023, 40, 501
DOI: 10.1007/s11095-022-03298-8