Xun Zhang, Zhongle Li, Huaya Yong and Zhixiang Xie
Org. Chem. Front., 2018,5, 3469-3475
DOI:
10.1039/C8QO00772A,
Research Article
Salyunnanin A and hassanane, two C23 terpenoids, were achieved from (+)-carnosic acid in 6 and 5 steps, respectively. The synthetic strategy was primarily inspired by the biogenetic hypothesis and provided access to the natural products via elimination, double Michael-type addition in one pot to prepare the corresponding 6,20-epoxyabietanes, and bismuthonium ylide induced ring expansion of o-quinone to construct 2-acyl-3-hydroxytropone.
