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Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives

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Identification of Unique Quinazolone Thiazoles as Novel Structural Scaffolds for Potential Gram-Negative Bacterial Conquerors

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Pioneering the Photoactive Relevance of Quinazolinone–Fullereropyrrolidine Nanohybrids To Address Chemotherapeutic Resistance in Cancer

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Anticoagulant Activity of Hybrid Molecules Based on 2,2,4-Trimethyl-4-aryl-1,2,3,4-tetrahydroquinoline and Nitrogen-Containing Heterocycles

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Development and Optimization of a Novel Synthetic Route for 2,4-Diamine-quinazoline Containing Ziresovir: A Drug Candidate for the Treatment of Respiratory Syncytial Virus (RSV) Infection

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A Bifurcated Multicomponent Synthesis Approach to Polycyclic Quinazolinones

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One-Pot Synthesis of Isoxazole-Fused Tricyclic Quinazoline Alkaloid Derivatives via Intramolecular Cycloaddition of Propargyl-Substituted Methyl Azaarenes under Metal-Free Conditions

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The Antibacterial Activity of Quinazoline and Quinazolinone Hybrids

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Photocatalysed eosin Y mediated synthesis of biologically potent 4 (3H)-quinazolinone

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Discovery of novel 1,2,3-Triazole hybrids derivatives as vasorelaxant agents: Molecular structure, Hirshfeld surface, in-vivo and in-silico investigation by molecular docking simulation

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Synthesis of Quinazolin-4(3H)-ones via a novel approach

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Visible Light‐Mediated Synthesis of Quinazoline and Quinazolinone Derivatives: A Quadrennial Update

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Recent Progress in Gold‐Catalyzed Reactions of Alkynes for the Construction of Indole Frameworks

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Synthesis and Biological Activities of Novel Quinazoline–Sulfonamide Derivatives Promising for the Treatment of Alzheimer's Disease

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Exploring Substituted Tetrazoloquinazoline: Biological Activities, Molecular Docking Analysis, and Anti‐Breast Cancer MCF7/HER2 Effects

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Synthesis and Theoretical Studies of Biologically Active Thieno Nucleus Incorporated Tri and Tetracyclic Nitrogen Containing Heterocyclics Scaffolds via Suzuki Cross‐Coupling Reaction

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MSCs as Tumor-Specific Vectors for the Delivery of Anticancer Agents—A Potential Therapeutic Strategy in Cancer Diseases: Perspectives for Quinazoline Derivatives

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Design, Synthesis and Biological Evaluation of 2-Phenylquinazolin-4-yl 4-Methylbenzenesulfonate Derivatives as Anticancer Agents via Tubulin Inhibition

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Grindstone Telescopic Approach for Pyrrolodiazepines Through Pictet‐Spengler‐Type Reaction and Solvent‐Free Synthesis of Quinazolines

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Symmetrical Bis-Hydrazone Ligand-Based Binuclear Oxido/Dioxido-Vanadium(IV/V) Complexes: Synthesis, Reactivity, and Catalytic Applications for the Synthesis of Biologically Potent 2-Phenylquinazolin-4-(3H)-ones

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Design and synthesis of N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as potential Werner-dependent antiproliferative agents

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Design and facile synthesis of quinazolinone-based full color-tunable boron difluoride dyes: Efficient solvent/solid-state emission and bioimaging application

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Recent Advances on Quinazoline Derivatives: A Potential Bioactive Scaffold in Medicinal Chemistry

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A Step-By-Step Synthesis of S-Methylene Linker Containing Triazole-Benzoxazole Hybrids by Click Chemistry Approach: Anticancer Activity in Human Cells

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Antibacterial Activity and Antifungal Activity of Monomeric Alkaloids

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Sildenafil (VIAGRATM): A Promising Anticancer Drug Against Certain Human Cancer Cell Lines

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Non-ribosomal peptide synthetase (NRPS)-encoding products and their biosynthetic logics in Fusarium

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Synthesis and antimicrobial evaluation of new quinazolinone derivatives containing thiourea and thiazolidine moieties

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Virtual screening and molecular dynamic simulations of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target

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Unveiling the Therapeutic Potential of Quinazolinone Derivatives in Cancer Treatment: A Comprehensive Exploration

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ChemistrySelect, 2024, 9
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2,3-Dihydroquinazolin-4(1H)-one as a New Class of Anti-Leishmanial Agents: A Combined Experimental and Computational Study

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Sequential Synthesis of Alkenylated Quinazolines Through sp3 C−H Functionalization and Their Photophysical Properties

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ChemistrySelect, 2024, 9
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Bio‐MOF‐11 Derived Amorphous Cobalt Hollow Nanospheres to Access Bioactive Quinazolinone Scaffolds and Aromatic Amines

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Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors

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Hexamethyldisilazane‐Mediated Synthesis of N‐Formamides, Benzimidazoles and Quinazolinones Using N,N‐Dimethylformamide as a C1 Source

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Green and sustainable approaches in the synthesis of pharmaceutically relevant quinazolinones

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Novel Quinazolinone–Isoxazoline Hybrids: Synthesis, Spectroscopic Characterization, and DFT Mechanistic Study

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Design, Synthesis, and Biological Evaluation of Novel Pyrazolo[1,5-a]pyrimidine and 1,3-Benzodiazine Derivatives as Potent Antitumor Agents

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Isatin based 1,2,3-triazole derivatives as antimicrobial agents: Synthesis, in silico docking and molecular dynamics simulations

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Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents

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BMC Chemistry, 2022, 16
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Theoretical and experimental investigation of novel quinazoline derivatives: synthesis, photophysical, reactive properties, molecular docking and selective HSA biointeraction

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One-pot synthesis of quinazolinone heterocyclic compounds using functionalized SBA-15 with natural material ellagic acid as a novel nanocatalyst

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Sci Rep, 2024, 14
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Design, synthesis and antitumor activity evaluation of 2,4,6-trisubstituted quinazoline derivatives containing piperidine moiety

Honglin Dai, Fuqiang Yu, Hao Wang, Lingling Chi, Chao Gao, Xiaojie Si, Yutong Zhang, Zhuo Qian, Peirong Zhao, Yingnan Zhu, Hongmin Liu and Qiurong Zhang

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Metal‐Free, Photoredox‐Catalyzed Synthesis of Quinazolin‐4(3H)‐ones and Benzo[4,5]imidazo[1,2‐c]quinazolines Using Trialkylamines as Alkyl Synthon

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Eur J Org Chem, 2023, 26
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BIOCHEMICAL BASIS OF THE ANTIMICROBIAL ACTIVITY OF QUINAZOLINONE DERIVATIVES IN THE LIGHT OF INSIGHTS INTO THE FEATURES OF THE CHEMICAL STRUCTURE AND WAYS OF BINDING TO TARGET MOLECULES. A REVIEW

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Synthesis, X-ray Structure, Hirshfeld, DFT and Biological Studies on a Quinazolinone-Nitrate Complex

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Synthesis of 2,3-dihydro-4(1 H) quinazolinones using a magnetic pectin-supported deep eutectic solvent

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Fenton‐Like Catalysis: Fe(III)/H2O2‐Mediated Oxidative Scission of Ascorbic Acid to a Sustainable One‐Carbon Approach for Aza‐Heterocycle Synthesis

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Asian J Org Chem, 2025
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A review on Fluoran compounds as widely used leuco dyes

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Design, Synthesis, and Antitumor Activity Evaluation of Novel 2,4,7-Trisubstituted Quinazoline Derivatives Containing an Aminomethyl Piperidine Moiety

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Medicinal Chemistry of Quinazolines as Anticancer Agents Targeting Tyrosine Kinases

Mohamed F. Zayed

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Palladium(II) N^O Chelating Complexes Catalyzed One-Pot Approach for Synthesis of Quinazolin-4(3H)-ones via Acceptorless Dehydrogenative Coupling of Benzyl Alcohols and 2-Aminobenzamide

Sundarraman Balaji, Gunasekaran Balamurugan, Rengan Ramesh and David Semeril

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Spectroscopic properties, crystal structure, Hirshfeld surface analysis and DFT study of a new Cu(II) complex based on quinazolinone O,N,O-donor ligand

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Rhodium-Catalyzed C–H Activation of 2-Arylquinazolinones and Cyclization with Elemental Sulfur via C–S/S–N Bond Formation to Access 7H-Benzo[4,5]isothiazolo[3,2-b]quinazolinones

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Recent advances and prospects in the organocatalytic synthesis of quinazolinones

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Front. Chem., 2022, 10
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Synthesis and bioactivities evaluation of quinazolin-4(3H)-one derivatives as α-glucosidase inhibitors

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BMC Chemistry, 2022, 16
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Pd-catalysed regioselective cross dehydrogenative coupling of quinazolinones with aromatic carboxylic acids

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Introducing Fe3O4@SiO2@KCC-1@MPTMS@CuII catalytic applications for the green one-pot syntheses of 2-aryl(or heteroaryl)-2,3-dihydroquinazolin-4(1H)-ones and 9-aryl-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones

Morteza Hasanpour Galehban, Behzad Zeynizadeh and Hossein Mousavi

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New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study

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C,N‐Diarylformamidines as Valuable Building Blocks in the Synthesis of Heterocyclic Compounds

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Copper-Catalyzed Decarboxylation Cross-Coupling Cascade Reaction for Synthesis of Fused Dihydro-benzoxazinones

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Activity-based protein profiling guided new target identification of quinazoline derivatives for expediting bactericide discovery

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Immobilization of Ni nanoparticles on pyridine-functionalized MWCNTs for indirect synthesis of benzimidazoles and quinazolinones, and their molecular docking studies as effective inhibitors of α-glucosidase

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Microwave Synthesized Hydrophilic 4‐Oxo‐2‐phenylquinazoline‐3(4H)–carboximidamide and –Carboxamide as Privileged Small Molecule Scaffolds with Anti‐HIV‐1 Activities

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ChemistrySelect, 2023, 8
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Base-Promoted [4 + 1 + 1] Multicomponent Tandem Cycloaddition of Ortho-Substituted Nitroarenes, Aldehydes, and Ammonium Salts To Access 2,4-Substituted Quinazoline Frameworks

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Cu‐Catalyzed Synthesis of [1,2,3]triazolo[1,5‐c]quinazolin‐5(6H)‐one Derivatives via Sequential Reaction of Ethyl‐2‐(2‐oxoindolin‐3‐ylidene)acetate with Sodium Azide

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Synthesis and evaluation of linearly fused thiadiazolocoumarins as prospects with broad-spectrum bioactivity

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Synthesis and Cytotoxicity Assay of Aniline Substituted Thienopyrimidines for Anti-Colorectal Cancer Activity

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Thiourea compounds as multifaceted bioactive agents in medicinal chemistry

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Synthesis and photophysical properties of pyridyl- and quinolinyl-substituted 4-(4-aminophenyl)quinazolines

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Synthesis, investigation of the crystal structure, DFT and in silico medicinal potential of nicotinonitrile substituted quinazolindione as potential anticancer scaffold

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Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells

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Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36, 1205
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Synthesis, Characterisation and Antimicrobial Activity of Novel 2-Methyl-3-(2-(substituted ylidene)hydrazinyl)quinazolin-4(3H)-ones

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6‐Bromoquinazoline Derivatives as Potent Anticancer Agents: Synthesis, Cytotoxic Evaluation, and Computational Studies

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Facile One-Pot Synthesis of Functionalized Quinoline-Fused Fluorescent Dihydro/Spiro-quinazolinone Derivatives

Kevin George, Pavithra Elavarasan, Shanmugam Ponnusamy and Kannadasan Sathananthan

ACS Omega, 2022, 7, 20605
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Palladium‐Catalyzed Three‐Component Process to [1,2,3]Triazolo [1,5‐c]quinazolines

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ChemistrySelect, 2024, 9
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New Quinazolinone‐Tethered 1,2,3‐Triazoles aSs Potent Antimicrobial Agents: Design, Synthesis, Biological Evaluation and in silico Docking Study

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ChemistrySelect, 2024, 9
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Synthesis and Evaluation of Antioxidant Properties of 2-Substituted Quinazolin-4(3H)-ones

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Molecules, 2021, 26, 6585
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Synthesis, Antimicrobial Evaluation, Molecular Docking and Dynamics Simulations of Novel 2,3‐Disubstituted Quinazolin‐4(3H)‐one Derivatives

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ChemistrySelect, 2024, 9
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Diversity oriented synthesis and SAR studies of new quinazolinones and related compounds as insecticidal agents against Culex pipiens L. Larvae and associated predator

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Bioorganic Chemistry, 2023, 133, 106436
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A Novel Powerful γ-Fe2O3 @ CPTMS - Diethylene Triamine (DETA) @SO3H as a Heterogeneous Nanocatalyst, Recyclable and Efficient via Microwave-assisted for the Synthesis of Benzoxazinone- 4(3H)-one Derivatives in Green Media

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Cyclizations of Alkenyl(Alkynyl)‐Functionalized Quinazolinones and their Heteroanalogues: A Powerful Strategy for the Construction of Polyheterocyclic Structures

Alla Vaskevych, Maryna Dekhtyar and Mykhailo Vovk

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Advances in the syntheses of alkaloid natural products and bioactive molecules based on ynamide building blocks

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Structure Confirmation of Quinazolinone and Hydroindole Using Residual Dipolar Couplings From Polyarylisocyanide Liquid Crystal

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Synthesis, Characterization, Antibacterial Evaluation, and Molecular Docking of New Quinazolinone-Based Derivatives

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Synthesis and hypoglycemic activity of new nicotinonitrile-furan molecular hybrids

D. A. Tilchenko, E. Yu. Bibik, V. V. Dotsenko, S. G. Krivokolysko, K. A. Frolov, N. A. Aksenov and I. V. Aksenova

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Synthesis and Biological Activities of Selenium/Thioether Quinazoline Compounds

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6-Amino-7-((4-methoxybenzyl)thio)quinazolin-4(3H)-one

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NNO Pincer Ligand-Supported Palladium(II) Complexes: Direct Synthesis of Quinazolines via Acceptorless Double Dehydrogenative Coupling of Alcohols

Balaji Sundarraman, Ramesh Rengan and David Semeril

Organometallics, 2022, 41, 1314
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A 1,2,3-Triazole Derivative of Quinazoline Exhibits Antitumor Activity by Tethering RNF168 to SQSTM1/P62

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Construction and characterization of Fe 3 O 4 @BAAH-CuCl nanomagnetic catalyst: catalysis research in synthesis of 2-aryl quinazolines from prepared benzylamines

Khalid Mujasam Batoo, Mohammed Kadhem Abid, Ayadh Al-Khalidi, Usama S. Altimari, Sajjad Hussain, Ahmed Alawadi, Ali Alsalamy and Hesham S. Mustafa

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Novel N-(3-ethynyl Phenyl)-6,7-bis(2-methoxyethoxy)Quinazoline-4-amine Derivatives: Synthesis, Characterization, Anti-cancer Activity, In-silico and DFT Studies

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Biocompatible chlorocoumarins from harmful chlorophenols, their synthesis and biomedicinal evaluation

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One‐Pot Three‐Component Cascade Synthesis of Pyrazolopyrido[2,3‐h]Quinazolines: Effective Fluorescent Turn‐Off Probes for Sensing Pd2+ Ions

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Study of the antimicrobial activity of new quinazoline derivatives against Staphylococcus aureus

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Quinazoline Derivatives as Potential Therapeutic Agents in Urinary Bladder Cancer Therapy

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Design, synthesis, anticancer activity and docking studies of novel quinazoline-based thiazole derivatives as EGFR kinase inhibitors

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Synthesis of novel quinazolinone-triheterocyclic hybrides as dual inhibition of urease and ache

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Transition-metal-catalyzed synthesis of quinazolines: A review

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Urea-based DES as an amine source to access nitrogen-containing heterocycles

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Medicinal Chemistry of Quinazolines as Analgesic and Anti-Inflammatory Agents

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Synthesis, biological evaluation, and in silico study of novel coumarin-quinazoline analogs as potential Anti-Angiogenesis agents

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Advances in Palladium‐Catalyzed Decarboxylative Cycloadditions of Cyclic Carbonates, Carbamates and Lactones

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Aminothiolation of 2-(2-bromophenyl)quinazolinones with elemental sulfur to access 7H-benzo[4,5]isothiazolo[3,2-b]quinazolinones through C–S/S–N bond formation under metal-free condition

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TFA-mediated nitrogenous heterocyclic assisted aldimine condensation/cyclization for the synthesis of pyrrolo[2′,1′:3,4]quinoxalino[1,2-c]quinazoline derivatives

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Enantioselective PCCP Brønsted acid-catalyzed aminalization of aldehydes

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Design, Synthesis and Pharmacological Evaluation of Novel 4-Phenoxyquinoline Derivatives as VEGFR2 Kinase Inhibitors for Tumor Treatment

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Green Approach for the Synthesis of 2-Phenyl-2H-indazoles and Quinazoline Derivatives Using Sustainable Heterogeneous Copper Oxide Nanoparticles Supported on Activated Carbon and OER Study

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