Issue 3, 2024

Protein-based bioactive coatings: from nanoarchitectonics to applications

Abstract

Protein-based bioactive coatings have emerged as a versatile and promising strategy for enhancing the performance and biocompatibility of diverse biomedical materials and devices. Through surface modification, these coatings confer novel biofunctional attributes, rendering the material highly bioactive. Their widespread adoption across various domains in recent years underscores their importance. This review systematically elucidates the behavior of protein-based bioactive coatings in organisms and expounds on their underlying mechanisms. Furthermore, it highlights notable advancements in artificial synthesis methodologies and their functional applications in vitro. A focal point is the delineation of assembly strategies employed in crafting protein-based bioactive coatings, which provides a guide for their expansion and sustained implementation. Finally, the current trends, challenges, and future directions of protein-based bioactive coatings are discussed.

Graphical abstract: Protein-based bioactive coatings: from nanoarchitectonics to applications

Article information

Article type
Review Article
Submitted
18 Ful 2023
First published
03 Ama 2024

Chem. Soc. Rev., 2024,53, 1514-1551

Protein-based bioactive coatings: from nanoarchitectonics to applications

C. Fu, Z. Wang, X. Zhou, B. Hu, C. Li and P. Yang, Chem. Soc. Rev., 2024, 53, 1514 DOI: 10.1039/D3CS00786C

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