Minoo Dabiri, Noushin Farajinia Lehi, Siyavash Kazemi Movahed and Hamid Reza Khavasi
Org. Biomol. Chem., 2017,15, 6264-6268
DOI:
10.1039/C7OB01534H,
Paper
A Pd-catalyzed ortho-selective halogenation of benzoxazinone and quinazolinone scaffolds has been described employing N-halosuccinimide as both a halogen source and an oxidant reagent via C–H bond activation. This transformation shows high chemo- and regioselectivities and demonstrates a broad range of benzoxazinone and quinazolinone substrates with different functional groups and has been scaled up to the gram level.
