Themed collection In memory of John S. Fossey – CAtalysis and SEnsing (CASE)

Switchable cyclophanes allow capture/release of guests to control their properties.

Gold nanoparticles and gold nanoshells functionalised with a selection of carbohydrates: glyco-nanoparticles towards lectin detection in a dipstick assay.

A novel pillar[5]arene-based supramolecular fluorescent probe was constructed for the real-time monitoring of the nonfluorescent drug gemcitabine delivered to cancer cells.

The synthesis of atropisomeric phosphino-triazoles through a CuAAC approach is disclosed. Gold(I) chloride complexes of single-enantiomer phosphines were then prepared and again demonstrated to be conformationally stable.

An ESIPT-based ratiometric probe with solid-state luminescence enhancement is developed for the sensitive detection of glycosidase activity.

We report the synthesis of a series of fluorophore and alkyne-derived 5,17-difunctionalised calix[4]arenes and their application in the detection of Au³⁺.

A supramolecular NIR nanophotosensitizer for dual-modal imaging and ablation of tumors was constructed by loading disulfiram (DSF) into the vesicle from host–guest complex of lactose-capped pillar[5]arene (LacP5) with aza-BODIPY derivative (BSTA).

Regio- and enantioselective Friedel–Crafts alkylation/N-hemiacetalization and dehydration sequence were reported using Ni(II)-PyBPI complex as catalyst, affording chiral 7-membered-ring-bridged 3,4-fused tricyclic indoles in good results.

Probe BocBDP with a binding unit suitable for penetrating the BBB and imaging Aβ in vivo.

The synthesis of chiral α-amino acid derived (1,2,3-triazol-4-yl)-picolinamide (tzpa) ligands 4–6 designed by combining the coordination properties of two well-known ligand structures within a single unit is described.

Characterization of chiral molecules in solution is paramount for measuring reaction success.

A dissipative self-assembly system based on G1 and G2 was fabricated by using dimethyl sulfate as chemical fuel. The mixed solution rapidly transformed into a hybrid hydrogel upon adding the fuel, accompanied by a significant emission enhancement.

An “indanonalkene” fluorescent chemosensor captured volatile amines via an amine–thiol scrambling reaction, and was applied to prepare portable paper-based sensors and polymeric film sensors for point-of-care detection of amines.

A NIR strong absorbing molecule was constructed by taking the structural advantages of a quinoid and diketopyrrolopyrrole, with an absorption maximum of up to 1039 nm and hole and electron mobilities up to 0.19 and 0.2 cm² V⁻¹ s⁻¹, respectively.

A calix[4]arene (1) functionalized with amidoindole groups on the upper rim and with propyl groups on the lower rim extracts LiCl and LiBr selectively.

THPIC was developed to detect HClO in lysosomes. The results showed that HClO could be used as a biomarker for evaluating drug-induced cardiotoxicity, and THPIC could be applied as a platform for screening drugs to prevent cardiotoxicitys.

An efficient synthesis of methylene-unsubstituted cyclopropane-fused indolines via photoredox catalyzed dearomative cyclopropanation of indole derivatives was developed.

We present a series of sterically demanding Eu(III) complexes and identify the optimal position of the peripheral phenylboronic acid to achieve the multisite recognition of AMP (adenosine monophosphate) in aqueous solution.

A library of 26 electron donor-acceptor organophotocatalysts based on the benzo[c][1,2,5]thiadiazole (BTZ) group has been developed. These visible light organophotocatalysts were then used in a Minisci-type alkylation of heteroarenes under both batch and continuous flow conditions.