The mechanism of the Ni-catalysed trifluoromethylthiolation of aryl chlorides using AgSCF3 is studied herein.
A mild silver-mediated cascade trifluoromethylthiolation/cyclization of unactivated alkenes with readily available AgSCF3 as the trifluoromethylthiolating reagent has been explored.
We reported a direct simple trifluoromethylthiolation reaction of various terminal alkynes using a new hypervalent trifluoromethylthio-iodine(III) reagent TFTI in a fluorinated alcohol, either hexafluoro-2-propanol or perfluoro-tert-butanol.
A copper-catalyzed ring-opening trifluoromethylthiolation/trifluoromethylselenolation of cyclopropanols with ArSO2SCF3 or ArSO2SeCF3 is developed.
Using S-trifluoromethyl thioesters as bifunctional reagents, we developed photoredox/copper dual-catalyzed 1,2-acyl-trifluoromethylthiolation of alkenes and 1,4-acyl-trifluoromethylthiolation of 1,3-enynes.