The first asymmetric synthetic route to artificial α-amino acids with a 3,4-dihydroisoquinolone skeleton was elaborated via a straightforward Rh(III)-catalyzed C–H activation/annulation reaction.
Unprecedented free amine-oriented regioselective activations/carbonylations mediated by hexacarbonylmolybdenum have been developed to synthesize 5/6-membered benzolactams respectively.
This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
The enantiomers of an arene ruthenium complex were separated by chromatography using auxiliary chiral phosphine. The resolved planar-chiral complex catalyzed asymmetric C–H activation of N-methoxy-benzamides.
This review demonstrates the redox-neutral synthetic approaches towards valuable heterocycles such as isoquinolines, indoles, isoquinolones, and tetrahydroquinolines via high-valent Cp*Co(III) catalysis.