The straightforward approach involving a [1,2]-aryl shift provides access to a wide range of aryl-substituted naphtho[2,1-b]furans. Switching of the regioselectivity of acid-catalyzed reactions of arylnaphtho[2,1-b]furans has been demonstrated.
Novel carbamothioate-mediated sulfonyl fluoride synthesis enables chalcone functionalization without Michael addition side reactions.
In this review, we present six methodologies for the synthesis of cyclooctyne derivatives, which are important reactants in bioorthogonal chemistry. Key aspects like the broad applicability and feasibility of these synthetic pathways are discussed.
To allow interaction studies using both 77Se and 19F-NMR, doubly Se/F-substituted compounds were synthesised. Interglycosidic seleno-linkages were formed by reactions between glycosyl selenoates, obtained from selenouronium salts, and triflates.
This review highlights key advances in the synthesis and biomolecular applications of sulfur(VI)-fluorides.