In Vivo Study of Local and Systemic Responses to Clinical Use of Mg–1Ca Bioresorbable Orthopedic Implants

Răzvan Adam, Iulian Antoniac, Silviu Negoiță, Cosmin Moldovan, Elena Rusu, Carmen Orban, Sorin Tudorache and Tudor Hârșovescu

Diagnostics, 2022, 12, 1966
DOI: 10.3390/diagnostics12081966

Microstructure refinement and in vivo evaluation of biodegradable magnesium metal matrix composites

Pedram Sotoudehbagha, Alison Grise, Andrew Romero, Andres Larraza, Sun Latt, Abel Córdova Flores, Kayley Romero, John Lovejoy and Mehdi Razavi

Journal of Materials Research and Technology, 2025, 39, 243
DOI: 10.1016/j.jmrt.2025.09.116

Property Variation of Extruded Mg-Gd Alloys by Mn Addition and Processing

Björn Wiese, Jochen Harmuth, Regine Willumeit-Römer and Jan Bohlen

Crystals, 2022, 12, 1036
DOI: 10.3390/cryst12081036

Magnesium alloys as extremely promising alternatives for temporary orthopedic implants – A review

C.A. Niranjan, T. Raghavendra, Madhuri P. Rao, C. Siddaraju, M. Gupta, Vikram Kumar S. Jain and R. Aishwarya

Journal of Magnesium and Alloys, 2023, 11, 2688
DOI: 10.1016/j.jma.2023.08.002

Inflammatory response toward a Mg-based metallic biomaterial implanted in a rat femur fracture model

Sana Riyaz, Yu Sun, Heike Helmholz, Tuula Penate Medina, Oula Penate Medina, Björn Wiese, Olga Will, Tamadur Albaraghtheh, Farhad Haj Mohamad, Jan-Bernd Hövener, Claus Christian Glüer and Regine Willumeit Römer

Acta Biomaterialia, 2024, 185, 41
DOI: 10.1016/j.actbio.2024.06.040

Development of Polymer–Metal Screw System for Bone Fracture Repair: Combining Strength and Biocompatibility

Ranveer Kaur, Sunil Kumar Yadav, Vivek Yadav, Arnab Sikidar, Sanyog Jain and Dinesh Kalyanasundaram

ACS Biomater. Sci. Eng., 2025, 11, 6561
DOI: 10.1021/acsbiomaterials.5c00191

Prospective evaluation of ultrasound features of magnesium-based bioabsorbable screw resorption in pediatric fractures

Stephan L. Waelti, Jozef Fandak, Stefan Markart, Erik P. Willems, Simon Wildermuth, Tim Fischer, Tobias J. Dietrich, Christoph Matissek and Thomas Krebs

Eur Radiol, 2023, 34, 1556
DOI: 10.1007/s00330-023-10091-7

Arginine–Silicate–Inositol Promotes Femoral Fracture Healing in Rats

Sukru Demir, Kazim Sahin, Ibrahim Hanifi Ozercan, Gokhan Once, Sefa Key and Murat Gurger

Biol Trace Elem Res, 2026
DOI: 10.1007/s12011-026-05085-7

Prospective Evaluation of Magnetic Resonance Imaging Features of Magnesium-Based Alloy Screw Resorption in Pediatric Fractures

Stephan L. Waelti, Simon Wildermuth, Erik P. Willems, Tim Fischer, Tobias J. Dietrich, Sebastian Leschka, Christoph Matissek, Thomas Krebs and Stefan Markart

JCM, 2023, 12, 3016
DOI: 10.3390/jcm12083016

Peri‐implant gas accumulation in response to magnesium‐based musculoskeletal biomaterials: Reframing current evidence for preclinical research and clinical evaluation

Yu Sun, Heike Helmholz and Regine Willumeit-Römer

Journal of Magnesium and Alloys, 2024, 12, 59
DOI: 10.1016/j.jma.2024.01.023

Insight into synergetic effects of serum albumin and glucose on the biodegradation behavior of WE43 alloy in simulated body fluid

Amin Imani, Amanda M Clifford, R K Singh Raman and Edouard Asselin

Biomed. Mater., 2023, 18, 015011
DOI: 10.1088/1748-605X/aca3e8

Systemic modulation of skeletal mineralization by magnesium implant promoting fracture healing: Radiological exploration enhanced with PCA-based machine learning in a rat femoral model

Yu Sun, Heike Helmholz and Regine Willumeit-Römer

Journal of Magnesium and Alloys, 2024, 12, 1009
DOI: 10.1016/j.jma.2024.01.012

Advancements in magnesium-based alloys for orthopedic implants: balancing corrosion, mechanical properties, and biological effects (part 1) – a review

L. Prawin Babu and R. Radha

Canadian Metallurgical Quarterly, 2025, 64, 2039
DOI: 10.1080/00084433.2024.2427455

The Recent Developments of Thermomechanical Processing for Biomedical Mg Alloys and Their Clinical Applications

Hui Zhao, Jing Cheng, Chaochao Zhao, Min Wen, Rui Wang, Di Wu, Zhaoying Wu, Fang Yang and Liyuan Sheng

Materials, 2025, 18, 1718
DOI: 10.3390/ma18081718

Degradation characteristics of high-purity magnesium implants under single static and cyclic compressive loads in vivo and in vitro

Long Guo, Xuanbin Zhang, Zhishan Zhang and Zhixiu Hao

Journal of Magnesium and Alloys, 2025, 13, 1480
DOI: 10.1016/j.jma.2024.12.014

Bone Response to Biodegradable Metals and In Vitro Evaluation of the Cytocompatibility

Edgar B. Montufar

JOM, 2025, 77, 4473
DOI: 10.1007/s11837-025-07353-8

Surgical Classification for Preclinical Rat Femoral Bone Defect Model: Standardization Based on Systematic Review, Anatomical Analysis and Virtual Surgery

Yu Sun, Heike Helmholz and Regine Willumeit-Römer

Bioengineering, 2022, 9, 476
DOI: 10.3390/bioengineering9090476

Effect of mechanical stresses on degradation behavior of high-purity magnesium in bone environments

Yan Yao, Jie Xia, Lizhen Wang, Yuanming Gao, Xili Ding, Chao Wang and Yubo Fan

Journal of Materials Science & Technology, 2024, 171, 252
DOI: 10.1016/j.jmst.2023.07.043

Multicolor Histochemical Staining for Identification of Mineralized and Non-Mineralized Musculoskeletal Tissue: Immunohistochemical and Radiological Validation in Decalcified Bone Samples

Yu Sun, Heike Helmholz and Regine Willumeit-Römer

Bioengineering, 2022, 9, 488
DOI: 10.3390/bioengineering9100488

Research progress of metal-based additive manufacturing in medical implants

Yun Zhai, Hao Zhang, Jianchuan Wang and Dewei Zhao

REVIEWS ON ADVANCED MATERIALS SCIENCE, 2023, 62
DOI: 10.1515/rams-2023-0148

Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys

Khurram Munir, Jixing Lin, Xian Tong, Arne Biesiekierski, Yuncang Li and Cuie Wen

Journal of Magnesium and Alloys, 2024, 12, 546
DOI: 10.1016/j.jma.2024.02.002