In situ time-resolved monitoring of mixed-ligand metal–organic framework mechanosynthesis

Max Rautenberg, Biswajit Bhattacharya, Julia Witt, Mohit Jain and Franziska Emmerling

CrystEngComm, 2022, 24, 6747
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Single-step synthesis of multicomponent cocrystals and salts: the role of laboratory seeding

Sampurna Nayak and Ashwini K. Nangia

CrystEngComm, 2024, 26, 5699
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In situ monitoring of mechanochemical synthesis of calcium urea phosphate fertilizer cocrystal reveals highly effective water-based autocatalysis

Patrick A. Julien, Luzia S. Germann, Hatem M. Titi, Martin Etter, Robert E. Dinnebier, Lohit Sharma, Jonas Baltrusaitis and Tomislav Friščić

Chem. Sci., 2020, 11, 2350
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Clues from cocrystals: a ternary solid, polymorphism, and rare supramolecular isomerism involving resveratrol and 5-fluorouracil

Celymar Ortiz-de León and Leonard R. MacGillivray

Chem. Commun., 2021, 57, 3809
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Co-crystallization of racemic amino acids with ZnCl2: an investigation of chiral selectivity upon coordination to the metal centre

Oleksii Shemchuk, Fabrizia Grepioni and Dario Braga

CrystEngComm, 2020, 22, 5613
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Mechanical approach for creating different molecular adducts and regulating salt polymorphs: a case study of the anti-inflammatory medication ensifentrine

Ananya Kar, Lopamudra Giri, Gowtham Kenguva, Smruti Rekha Rout and Rambabu Dandela

RSC Mechanochem., 2024, 1, 437
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Controlling polymorphism in molecular cocrystals by variable temperature ball milling

Kevin Linberg, Bettina Röder, Dominik Al-Sabbagh, Franziska Emmerling and Adam A. L. Michalchuk

Faraday Discuss., 2023, 241, 178
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The mechanochemical excitation of crystalline LiN3

Adam A. L. Michalchuk

Faraday Discuss., 2023, 241, 230
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Enhancing the stability of active pharmaceutical ingredients by the cocrystal strategy

Liyu Liu, Jian-Rong Wang and Xuefeng Mei

CrystEngComm, 2022, 24, 2002
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Kinetics of the mechanically induced ibuprofen–nicotinamide co-crystal formation by in situ X-ray diffraction

Lucia Casali, Maria Carta, Adam A. L. Michalchuk, Francesco Delogu and Franziska Emmerling

Phys. Chem. Chem. Phys., 2024, 26, 22041
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Green Mechanochemical Preparation of Cocrystal Polymorphs: Significant Effect of Intermediates and Solvents

Luguang Qi, Chang Li, Xiaowei Cheng, Hongxun Hao and Chuang Xie

Crystal Growth & Design, 2024, 24, 6196
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Multicomponent Crystals with Competing Intermolecular Interactions: In Situ X‐ray Diffraction and Luminescent Features Reveal Multimolecular Assembly under Mechanochemical Conditions

Yoshio Yano, Hidetaka Kasai, Yanyan Zheng, Eiji Nishibori, Yoshio Hisaeda and Toshikazu Ono

Angew Chem Int Ed, 2022, 61
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Structural and computational insights into ternary cocrystals of succinimide with 3-nitrophthalic acid and urea

Jyothi K. L, Udaya Kumar A. H, Karthik Kumara, Vallabh S. Ghantasala, Arya Viswanath M and Lokanath N. K

Journal of Molecular Structure, 2026, 1359, 145400
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Zeitaufgelöste In‐Situ‐Untersuchungen von mechanochemischen Reaktionen

Adam A. L. Michalchuk and Franziska Emmerling

Angewandte Chemie, 2022, 134
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Multicomponent Crystals with Competing Intermolecular Interactions: In Situ X‐ray Diffraction and Luminescent Features Reveal Multimolecular Assembly under Mechanochemical Conditions

Yoshio Yano, Hidetaka Kasai, Yanyan Zheng, Eiji Nishibori, Yoshio Hisaeda and Toshikazu Ono

Angewandte Chemie, 2022, 134
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Mechanochemical Synthesis of Cocrystal: From Mechanism to Application

Yuntian Xiao, Chuanhua Wu, Xingchen Hu, Kui Chen, Luguang Qi, Pingping Cui, Ling Zhou and Qiuxiang Yin

Crystal Growth & Design, 2023, 23, 4680
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An integrated experimental and theoretical research on ternary salt-cocrystal of anti-heart failure medicine milrinone with different substituted benzoic acids

Fan-Zhi Bu, Su-Su Meng, Ling-Yang Wang, Zhi-Yong Wu and Yan-Tuan Li

Journal of Molecular Structure, 2024, 1304, 137685
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Energetic Cocrystallization as the Most Significant Crystal Engineering Way to Create New Energetic Materials

Guangrui Liu, Rupeng Bu, Xin Huang, Kai Zhong, Fangbao Jiao, Su-Huai Wei, Hongzhen Li and Chaoyang Zhang

Crystal Growth & Design, 2022, 22, 954
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Trimesic Acid as a Building Block for Ternary and Quaternary Salts and Salt Cocrystals

Lamis Alaa Eldin Refat, Marwah Aljohani and Andrea Erxleben

Crystal Growth & Design, 2024, 24, 9403
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Outstanding Advantages, Current Drawbacks, and Significant Recent Developments in Mechanochemistry: A Perspective View

Silvina Pagola

Crystals, 2023, 13, 124
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Cocrystals “Divorce and Marriage”: When a Binary System Meets an Active Multifunctional Synthon in a Ball Mill

Marta K. Dudek, Justyna Śniechowska, Aneta Wróblewska, Sławomir Kaźmierski and Marek J. Potrzebowski

Chemistry A European J, 2020, 26, 13264
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Cocrystallization-Driven Double-Optimized Stratagem toward Directional Self-Assembly for the First Ternary Salt Cocrystal of Cardiotonic Drug Milrinone with Different Phenolic Acids Exhibits Optimal In Vitro/Vivo Biopharmaceutical Peculiarities

Su-Su Meng, Yue-Ming Yu, Fan-Zhi Bu, Cui-Wei Yan, Zhi-Yong Wu and Yan-Tuan Li

Mol. Pharmaceutics, 2023, 20, 3598
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Mechanochemical Metathesis between AgNO3 and NaX (X = Cl, Br, I) and Ag2XNO3 Double-Salt Formation

Stipe Lukin, Tomislav Stolar, Ivor Lončarić, Igor Milanović, Nikola Biliškov, Marco di Michiel, Tomislav Friščić and Ivan Halasz

Inorg. Chem., 2020, 59, 12200
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Green Mechanochemical Strategy for the Construction of a New Bio-based Nylon 524T Ternary Salt

Pengpeng Yang, Xiaojie Li, Zihan Li, Xincao Fang, Keke Zhang, Wei Zhuang, Jinglan Wu, Chenjie Zhu and Hanjie Ying

ACS Sustainable Chem. Eng., 2022, 10, 3513
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Raman spectroscopy for real-time and in situ monitoring of mechanochemical milling reactions

Stipe Lukin, Krunoslav Užarević and Ivan Halasz

Nat Protoc, 2021, 16, 3492
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Real-Time Spectroscopic and Microscopic Investigations of Solid-State Reaction of Schiff Bases and Their Optical-Waveguiding Properties

Bhargav Jyoti Bora, Vuppu Vinay Pradeep, Tanari Pratap, Akella Sai Radha Aishwarya and Mari Annadhasan

ACS Appl. Opt. Mater., 2025, 3, 1057
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Time‐Resolved In Situ Monitoring of Mechanochemical Reactions

Adam A. L. Michalchuk and Franziska Emmerling

Angew Chem Int Ed, 2022, 61
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Mechanosynthesis of Eutectics of Anti‐Inflammatory Drug Ethenzamide – A Comparison with Analogous Cocrystals

Trishna Rajbongshi, Kashyap Kumar Sarmah, Ramesh Ganduri, Suryanarayan Cherukuvada, Mihails Arhangelskis and Ranjit Thakuria

Chemistry Methods, 2021, 1, 408
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Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals

Aneta Wróblewska, Justyna Śniechowska, Sławomir Kaźmierski, Ewelina Wielgus, Grzegorz D. Bujacz, Grzegorz Mlostoń, Arkadiusz Chworos, Justyna Suwara and Marek J. Potrzebowski

Pharmaceutics, 2020, 12, 359
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Efficient cocrystal coformer screening based on a Machine learning Strategy: A case study for the preparation of imatinib cocrystal with enhanced physicochemical properties

Xiaoxiao Liang, Shiyuan Liu, Zebin Li, Yuehua Deng, Yanbin Jiang and Huaiyu Yang

European Journal of Pharmaceutics and Biopharmaceutics, 2024, 196, 114201
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Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals

Mizraín Solares-Briones, Guadalupe Coyote-Dotor, José C. Páez-Franco, Miriam R. Zermeño-Ortega, Carmen Myriam de la O Contreras, Daniel Canseco-González, Alcives Avila-Sorrosa, David Morales-Morales and Juan M. Germán-Acacio

Pharmaceutics, 2021, 13, 790
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Dispersive x-ray absorption spectroscopy for time-resolved in situ monitoring of mechanochemical reactions

Ana Guilherme Buzanich, C. Tufan Cakir, Martin Radtke, M. Bilal Haider, Franziska Emmerling, Paulo F. M. de Oliveira and Adam A. L. Michalchuk

The Journal of Chemical Physics, 2022, 157
DOI: 10.1063/5.0130673