A biodegradable block polyurethane nerve-guidance scaffold enhancing rapid vascularization and promoting reconstruction of transected sciatic nerve in Sprague-Dawley rats

Yuqing Niu and Massimiliano Galluzzi

J. Mater. Chem. B, 2020, 8, 11063
DOI: 10.1039/D0TB02069A

Natural-Based Biomaterials for Peripheral Nerve Injury Repair

Benedetta E. Fornasari, Giacomo Carta, Giovanna Gambarotta and Stefania Raimondo

Front. Bioeng. Biotechnol., 2020, 8
DOI: 10.3389/fbioe.2020.554257

Material advancement in tissue-engineered nerve conduit

Wufei Dai, Yating Yang, Yumin Yang and Wei Liu

Nanotechnology Reviews, 2021, 10, 488
DOI: 10.1515/ntrev-2021-0028

Silk fibroin-hyaluronic acid nanofibers for peripheral nerve regeneration

Madeline R Badrak, Judy Senanayake, Ahmad Zunnu Rain and Harini G Sundararaghavan

J Biomater Appl, 2025, 40, 307
DOI: 10.1177/08853282251329315

Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis

Silvia Biggi, Giulia A. Bassani, Valentina Vincoli, Daniele Peroni, Valerio Bonaldo, Marco Biagiotti, Romina Belli, Antonio Alessandrino, Emiliano Biasini and Giuliano Freddi

ACS Appl. Bio Mater., 2020, 3, 8361
DOI: 10.1021/acsabm.0c00613

Use of Bombyx mori silk fibroin in tissue engineering: From cocoons to medical devices, challenges, and future perspectives

Alessio Bucciarelli and Antonella Motta

Biomaterials Advances, 2022, 139, 212982
DOI: 10.1016/j.bioadv.2022.212982

Nanopore structure of PLA@SF aligned composite electrospun fiber membrane enhances growth behavior of peripheral nerve cells

Tao Feng, Yanfang Liu, Yehua Lv, Yang Shao, Lifeng Niu and Daguo Mi

Front. Mater., 2025, 12
DOI: 10.3389/fmats.2025.1570738

Digital nerve reconstruction with a new composite silk fibroin nerve conduit

Olga Politikou, Florian S. Frueh, Martina Greminger, Inga S. Besmens, Giuliano Freddi, Antonio Alessandrino and Maurizio Calcagni

J Peripheral Nervous Sys, 2025, 30
DOI: 10.1111/jns.12675

Novel genipin-crosslinked acellular biogenic conduits for tissue engineering applications

Óscar Darío García-García, Sandra Escalante-Quirós, Claudia Llinares-Monllor, Paula Ávila-Fernández, David Sánchez-Porras, Miguel Etayo-Escanilla, Fernando Campos, Jesús Chato-Astrain and Víctor Carriel

Biomedicine & Pharmacotherapy, 2025, 187, 118064
DOI: 10.1016/j.biopha.2025.118064

Biodegradable polymeric conduits: Platform materials for guided nerve regeneration and vascular tissue engineering

Uzma Hayat, Ali Raza, Muhammad Bilal, Hafiz M.N. Iqbal and Jin-Ye Wang

Journal of Drug Delivery Science and Technology, 2022, 67, 103014
DOI: 10.1016/j.jddst.2021.103014

The progress of biomaterials in peripheral nerve repair and regeneration

Yimeng Wang, Yuan Zhang, Xuemin Li and Qiqing Zhang

Journal of Neurorestoratology, 2020, 8, 252
DOI: 10.26599/JNR.2020.9040022

Silk fibroin-based scaffolds for tissue engineering

Li Ma, Wenyuan Dong, Enping Lai and Jiamian Wang

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1381838

Two Sides of Electrospun Fiber in Promoting and Inhibiting Biomedical Processes

Zhen Wang and Wenguo Cui

Advanced Therapeutics, 2021, 4
DOI: 10.1002/adtp.202000096

Biomaterials and tissue engineering strategies for management of neurodegeneration: A critical perspective

Suraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Javedh Shareef and Tarun Wadhwa

Medicine in Novel Technology and Devices, 2025, 26, 100369
DOI: 10.1016/j.medntd.2025.100369

Biomaterials for Regenerative Medicine in Italy: Brief State of the Art of the Principal Research Centers

Francesca Camponogara, Federica Zanotti, Martina Trentini, Elena Tiengo, Ilaria Zanolla, Elham Pishavar, Elisa Soliani, Marco Scatto, Paolo Gargiulo, Ylenia Zambito, Luca De Stefano, Letizia Ferroni and Barbara Zavan

IJMS, 2022, 23, 8245
DOI: 10.3390/ijms23158245

Facilitation of Cell Cycle and Cellular Migration of Rat Schwann Cells by O‐Carboxymethyl Chitosan to Support Peripheral Nerve Regeneration

Zhiwen Jiang, Wei Zhang, Chenqi Liu, Lixin Xia, Shuo Wang, Yanting Wang, Kai Shao and Baoqin Han

Macromolecular Bioscience, 2023, 23
DOI: 10.1002/mabi.202300025

Fabrication of PBS/PLA/Fibroin-Agarose nerve guidance conduit with sandwich compression resistant wall structure for repairment of 10 mm-sciatic nerve defect

Wen Zhang, Meng-Fei Hao, Hao Peng, Dong-Yi Wei, Jing-Jing Yao, Tian Guo, Li-Min Yang and Hua-Jie Wang

Chemical Engineering Journal, 2025, 505, 159312
DOI: 10.1016/j.cej.2025.159312

Graphene oxide and electroactive reduced graphene oxide-based composite fibrous scaffolds for engineering excitable nerve tissue

Adrián Magaz, Xu Li, Julie E. Gough and Jonny J. Blaker

Materials Science and Engineering: C, 2021, 119, 111632
DOI: 10.1016/j.msec.2020.111632

Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport

Hao Bai, Siqi Zhang, Huiran Yang, Jing Wang, Hongli Chen, Jia Li, Lin Li, Qian Yang, Bo Peng, Ziyi Zhu, Siyuan Ni, Keyin Liu, Wei Lei, Tiger H. Tao and Yafei Feng

Bioactive Materials, 2024, 39, 287
DOI: 10.1016/j.bioactmat.2024.05.033

Studies on effect of temperature on carbonization of silk (Bombyx mori) and its application as proximity sensor

Shubhanth Jain, R.V. Prajwal, V. Vedavyas, S. Vishwas and Govindaraj Achutharao

Carbon Trends, 2023, 13, 100314
DOI: 10.1016/j.cartre.2023.100314

Implantable nerve guidance conduits: Material combinations, multi-functional strategies and advanced engineering innovations

Yixin Yan, Ruotong Yao, Jingyuan Zhao, Kaili Chen, Lirong Duan, Tian Wang, Shujun Zhang, Jinping Guan, Zhaozhu Zheng, Xiaoqin Wang, Zekun Liu, Yi Li and Gang Li

Bioactive Materials, 2022, 11, 57
DOI: 10.1016/j.bioactmat.2021.09.030

Preclinical Validation of SilkBridgeTM for Peripheral Nerve Regeneration

Federica Fregnan, Luisa Muratori, Giulia A. Bassani, Alessandro Crosio, Marco Biagiotti, Valentina Vincoli, Giacomo Carta, Pasquale Pierimarchi, Stefano Geuna, Antonio Alessandrino, Giuliano Freddi and Giulia Ronchi

Front. Bioeng. Biotechnol., 2020, 8
DOI: 10.3389/fbioe.2020.00835

Advancements in Silkworm-Derived Silk Fibroin Biomaterials for Peripheral Nerve Regeneration

Jitu Mani Das, Isha Behere, Jnanendra Upadhyay, Rajiv Borah and Ganesh Ingavle

OBM Neurobiol, 2025, 09, 1
DOI: 10.21926/obm.neurobiol.2501265

Evaluation of Viability and Cell Attachment of Human Endometrial Stem Cells on Electrospun Silk Scaffolds Prepared Under Different Degumming Conditions and Solvents

Jamileh Saremi, Zeinab Zarei-Behjani, Elham Vojoudi and Somayeh Ebrahimi-Barough

Regen. Eng. Transl. Med., 2022, 8, 593
DOI: 10.1007/s40883-022-00258-x

Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze–thaw process

Tomoki Matsuo, Hiroo Kimura, Takayuki Nishijima, Yasuhiro Kiyota, Taku Suzuki, Narihito Nagoshi, Shinsuke Shibata, Tomoko Shindo, Nobuko Moritoki, Makoto Sasaki, Sarara Noguchi, Yasushi Tamada, Masaya Nakamura and Takuji Iwamoto

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-88221-y

Advanced Bioactive Polymers and Materials for Nerve Repair: Strategies and Mechanistic Insights

Nidhi Puranik, Shraddha Tiwari, Meenakshi Kumari, Shiv Kumar Yadav, Thakur Dhakal and Minseok Song

JFB, 2025, 16, 255
DOI: 10.3390/jfb16070255

The Materiobiology of Silk: Exploring the Biophysical Influence of Silk Biomaterials on Directing Cellular Behaviors

Dakshi Kochhar, Megan K. DeBari and Rosalyn D. Abbott

Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.697981

Emerging polymeric biomaterials and manufacturing-based tissue engineering approaches for neuro regeneration-A critical review on recent effective approaches

Amna Akhtar, Vahideh Farzam Rad, Ali-Reza Moradi, Muhammad Yar and Masoomeh Bazzar

Smart Materials in Medicine, 2023, 4, 337
DOI: 10.1016/j.smaim.2022.11.007

Perspective Insights to Bio-Nanomaterials for the Treatment of Neurological Disorders

Johra Khan, Mithun Rudrapal, Eijaz Ahmed Bhat, Ahmad Ali, Mohammad Alaidarous, Bader Alshehri, Saeed Banwas, Randa Ismail and Chukwuebuka Egbuna

Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.724158

Tissue-Engineered Core–Shell Silk-Fibroin/Poly-l-Lactic Acid Nerve Guidance Conduit Containing Encapsulated Exosomes of Human Endometrial Stem Cells Promotes Peripheral Nerve Regeneration

Mojdeh Salehi Namini, Somayeh Ebrahimi-Barough, Jafar Ai, Hossein Kargar Jahromi, Elmira mikaeiliagah, Mahmoud Azami, Naghmeh Bahrami, Nasrin Lotfibakhshaiesh, Jamileh Saremi and Sadegh Shirian

ACS Biomater. Sci. Eng., 2023, 9, 3496
DOI: 10.1021/acsbiomaterials.3c00157

Modulation of Neuronal Cell Affinity on PEDOT–PSS Nonwoven Silk Scaffolds for Neural Tissue Engineering

Adrián Magaz, Ben F. Spencer, John G. Hardy, Xu Li, Julie E. Gough and Jonny J. Blaker

ACS Biomater. Sci. Eng., 2020, 6, 6906
DOI: 10.1021/acsbiomaterials.0c01239

Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction

Marco Biagiotti, Giulia Alessandra Bassani, Anna Chiarini, Valentina Teodolinda Vincoli, Ilaria Dal Prà, Cesare Cosentino, Antonio Alessandrino, Paola Taddei and Giuliano Freddi

Front. Bioeng. Biotechnol., 2022, 10
DOI: 10.3389/fbioe.2022.833157

Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival

Zhiwen Jiang, Yijie Zhang, Yanting Wang, Shuo Wang, Jing Chang, Wanshun Liu and Baoqin Han

Carbohydrate Polymers, 2023, 301, 120327
DOI: 10.1016/j.carbpol.2022.120327

Exploration of biomaterial and stem cell-based strategies for promoting neuronal regeneration and creating engineered 3D in-vitro disease models

Gopal Khodve, Sayani Banerjee, Mamta Kumari, Velayutham Ravichandiran, Sugato Banerjee and Subhadeep Roy

J Transl Med, 2025, 23
DOI: 10.1186/s12967-025-07266-9

A brief review on the mechanisms and approaches of silk spinning-inspired biofabrication

Xuan Mu, Reza Amouzandeh, Hannah Vogts, Elise Luallen and Milad Arzani

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1252499

A Route to Translate a Silk-Based Medical Device from Lab to Clinic: The Silk Biomaterials Srl Experience

Giulia Alessandra Bassani, Valentina Vincoli, Marco Biagiotti, Elisa Valsecchi, Marta Virginia Zucca, Claudia Clavelli, Antonio Alessandrino and Giuliano Freddi

Insects, 2022, 13, 212
DOI: 10.3390/insects13020212