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RSC Med. Chem., 2020, 11, 969
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Medicinal Chemistry Insights in the Discovery of Novel LSD1 Inhibitors

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Epigenomics, 2015, 7, 1379
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Drug Discovery Researches on Modulators of Lysine-Modifying Enzymes Based on Strategic Chemistry Approaches

Yukihiro Itoh

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Medicinal Chemistry Research on Targeting Epigenetic Complexes

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Tranylcypromine-derived LSD1 inhibitors: Synthetic strategies, structure-activity relationships, and anticancer potential

Khursheed Ahmad Sheikh, Siddiqui Muzammil, Elaf Raneem, Mymoona Akhter, Tariq Anwer, Meenu, Shyama Charan, Mohammad Kaleem, Md. Khalid Saifullah, M. Mumtaz Alam and M. Shaquiquzzaman

European Journal of Medicinal Chemistry, 2025, 299, 118054
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Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1

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ACS Omega, 2020, 5, 3979
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Development and Structural Evaluation of N‐Alkylated trans‐2‐Phenylcyclopropylamine‐Based LSD1 Inhibitors

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ChemMedChem, 2020, 15, 787
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Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures

Yosuke Ota, Taeko Kakizawa, Yukihiro Itoh and Takayoshi Suzuki

Molecules, 2018, 23, 1099
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Recent Progress in Histone Demethylase Inhibitors

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Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases

Hideaki Niwa and Takashi Umehara

Epigenetics, 2017, 12, 340
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Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity

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Bioorganic & Medicinal Chemistry, 2017, 25, 847
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Pharmacological Inhibition of LSD1 for Cancer Treatment

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Molecules, 2018, 23, 3194
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A Systematic Review of Histone Lysine‐Specific Demethylase 1 and Its Inhibitors

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Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles

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ACS Med. Chem. Lett., 2022, 13, 848
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Histone Lysine Demethylase Inhibitors

Ashwini Jambhekar, Jamie N. Anastas and Yang Shi

Cold Spring Harb Perspect Med, 2017, 7, a026484
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Inhibitors of Protein Methyltransferases and Demethylases

H. Ümit Kaniskan, Michael L. Martini and Jian Jin

Chem. Rev., 2018, 118, 989
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Drug Design Concepts for LSD1‐Selective Inhibitors

Yosuke Ota and Takayoshi Suzuki

The Chemical Record, 2018, 18, 1782
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Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors

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Bioorganic & Medicinal Chemistry, 2018, 26, 775
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Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective

Xing-Jie Dai, Ying Liu, Xiao-Peng Xiong, Lei-Peng Xue, Yi-Chao Zheng and Hong-Min Liu

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Molecular Technology for Controlling Epigenetics: Regulation of Histone Acetylation and Methylation by Small Molecules

Yukihiro Itoh and Takayoshi Suzuki

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Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitors

Taeko Kakizawa, Yosuke Ota, Yukihiro Itoh and Takayoshi Suzuki

Bioorganic & Medicinal Chemistry Letters, 2018, 28, 167
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TCPs: Privileged Scaffolds for Identifying Potent LSD1 Inhibitors for Cancer Therapy

Yi-Chao Zheng, Bin Yu, Zhe-Sheng Chen, Ying Liu and Hong-Min Liu

Epigenomics, 2016, 8, 651
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Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators

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