A step-ladder manganese(iii) metallacrown hosting mefenamic acid and a manganese(ii)–mefanamato complex: synthesis, characterization and cytotoxic activity

Alketa Tarushi, George D. Geromichalos, Kostas Lafazanis, Catherine P. Raptopoulou, Vassilis Psycharis, Nikolia Lalioti, Anastasia A. Pantazaki, Dimitris P. Kessissoglou, Vassilis Tangoulis and George Psomas

New J. Chem., 2018, 42, 6955
DOI: 10.1039/C8NJ01182F

Investigation of novel Mn(ii) fenamato complexes with neocuproine and their effects on endometrial cell lines

Zuzana Klepcová, Ivana Špaková, Corina T. Madreiter-Sokolowski, Wolfgang Graier, Katarína Kalinová, Erika Samoľová, Romana Smolková, Lukáš Smolko and Miroslava Rabajdová

New J. Chem., 2023, 47, 13088
DOI: 10.1039/D3NJ00412K

Novel mefenamic acid PVC membrane sensor based on a new Cd Schiff's base complex containing a phenanthroline unit

Mohammad Noroozi and Hassan Keypour

RSC Adv., 2017, 7, 39118
DOI: 10.1039/C7RA06821B

Manganese(ii) complexes with the non-steroidal anti-inflammatory drugs naproxen and mefenamic acid: synthesis, structure, antioxidant capacity, and interaction with albumins and DNA

Filitsa Dimiza, Catherine P. Raptopoulou, Vassilis Psycharis, Athanasios N. Papadopoulos and George Psomas

New J. Chem., 2018, 42, 16666
DOI: 10.1039/C8NJ03226B

Ruthenium(ii) arene NSAID complexes: inhibition of cyclooxygenase and antiproliferative activity against cancer cell lines

Poulami Mandal, Bidyut Kumar Kundu, Komal Vyas, Vidya Sabu, A. Helen, Sandeep Singh Dhankhar, C. M. Nagaraja, Debojit Bhattacherjee, Krishna Pada Bhabak and Suman Mukhopadhyay

Dalton Trans., 2018, 47, 517
DOI: 10.1039/C7DT03637J

Ruthenium–arene complexes with NSAIDs: synthesis, characterization and bioactivity

Ana Tadić, Jelena Poljarević, Milena Krstić, Marijana Kajzerberger, Sandra Aranđelović, Siniša Radulović, Chrisoula Kakoulidou, Athanasios N. Papadopoulos, George Psomas and Sanja Grgurić-Šipka

New J. Chem., 2018, 42, 3001
DOI: 10.1039/C7NJ04416J

Synthesis and characterization of quantum dots for application in laser soft desorption/ionization mass spectrometry to detect labile metal–drug interactions and their antibacterial activity

Hani Nasser Abdelhamid and Hui-Fen Wu

RSC Adv., 2015, 5, 76107
DOI: 10.1039/C5RA11301F

Synthesis, characterisation, crystal structure and biological activity of metal(II) complexes with theophylline

Michał Gacki, Karolina Kafarska, Anna Pietrzak, Izabela Korona-Glowniak and Wojciech M. Wolf

Journal of Saudi Chemical Society, 2019, 23, 346
DOI: 10.1016/j.jscs.2018.08.006

Intercalation of manganese-mefenamic acid complex into double stranded of calf thymus DNA

Nahid Shahabadi, Zeinab jamshidi, Saba Hadidi, Farshad Shiri and Navid Fatahi

Nucleosides, Nucleotides and Nucleic Acids, 2019, 38, 901
DOI: 10.1080/15257770.2019.1625379

New Mn(II) Mefenamates Appended by Substituted Bipyridine Linkers: Structural, Thermal, Magnetic, and Biological Investigations

Beena Kanta Vernekar, Luann Romayne D'souza, Kedar Umakant Narvekar, Sanket Krishnanath Gaonkar and Pradip Kumar Bhowmik

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202502302

The future of drug Monitoring: Highly selective ratiometric sensing of mefenamic acid by simple AIEE active probe supported through Extensive fluorometric and DFT studies

Abdul Majeed, Mohammed A. Assiri, Hasher Irshad, Khadija, Muhammad Zahid Ullah and Sohail Anjum Shahzad

Microchemical Journal, 2024, 201, 110640
DOI: 10.1016/j.microc.2024.110640

Synthesis, structure and biological activity of nickel(II) complexes with mefenamato and nitrogen-donor ligands

Xanthippi Totta, Aikaterini A. Papadopoulou, Antonios G. Hatzidimitriou, Athanasios Papadopoulos and George Psomas

Journal of Inorganic Biochemistry, 2015, 145, 79
DOI: 10.1016/j.jinorgbio.2015.01.009

Silver(I) Complexes with Mefenamic Acid and Nitrogen Heterocyclic Ligands: Synthesis, Characterization, and Biological Evaluation

Lu-Lin Zhang, Xiang Huang, Mohammad Azam, Hua-Xin Yuan, Feng-Jie Ma, Yuan-Zheng Cheng, Li-Ping Zhang and Di Sun

Inorg. Chem., 2024, 63, 12624
DOI: 10.1021/acs.inorgchem.4c01766

Ibuprofenato cobalt complexes: Structural insights, DNA interaction studies, and biological evaluation

Beena K. Vernekar, Jaxon R. Breckell, Raymond J. Butcher, Deepika Maliwal, Raghuvir R.S. Pissurlenkar, Sanket K. Gaonkar, Delicia A. Barretto, Saurav D. Sattarker and Christopher Richardson

Journal of Molecular Structure, 2026, 1349, 143635
DOI: 10.1016/j.molstruc.2025.143635

Computational insight into the phthalocyanine-DNA binding via docking and molecular dynamics simulations

Lalehan Ozalp, Safiye Sağ Erdem, Başak Yüce-Dursun, Özal Mutlu and Mehmet Özbil

Computational Biology and Chemistry, 2018, 77, 87
DOI: 10.1016/j.compbiolchem.2018.09.009

Cobalt(II) complexes containing mefenamic acid with imidazole and pyridine based auxiliary ligands: Synthesis, structural investigation and cytotoxic evaluation

Ginikachukwu Grace Nnabuike, Sunita Salunke-Gawali, Archana S. Patil, Ray J. Butcher, Joshua Ayoola Obaleye, Harsha Ashtekar and Bharathi Prakash

Journal of Molecular Structure, 2023, 1285, 135519
DOI: 10.1016/j.molstruc.2023.135519

Cobalt(II) complexes with non-steroidal anti-inflammatory drugs and α-diimines

Sofia Tsiliou, Lida-Aikaterini Kefala, Antonios G. Hatzidimitriou, Dimitris P. Kessissoglou, Franc Perdih, Athanasios N. Papadopoulos, Iztok Turel and George Psomas

Journal of Inorganic Biochemistry, 2016, 160, 125
DOI: 10.1016/j.jinorgbio.2015.12.015

Synthesis, characterization and thermal behavior of solid state of some mefenamate of trivalent lanthanides (La, Ce, Pr and Nd)

Francisco X. Campos, André L. C. S. Nascimento, Tiago A. D. Colman, Diogo A. Gálico, Oswaldo Treu-Filho, Flávio J. Caires, Adriano B. Siqueira and Massao Ionashiro

J Therm Anal Calorim, 2016, 123, 91
DOI: 10.1007/s10973-015-4956-7

Manganese(II) Complexes with Non-Steroidal Anti-Inflammatory Drugs: Structure and Biological Activity

Filitsa Dimiza, Antonios G. Hatzidimitriou and George Psomas

IJMS, 2024, 25, 13457
DOI: 10.3390/ijms252413457

Synthesis, Crystal Structures and Binding Studies of Flufenamic‐ Acid‐Based Metal Complexes

Vineet Kumar, Shailabh Tewari, Balendra, Sandip Karmakar and Arunachalam Ramanan

ChemistrySelect, 2018, 3, 7689
DOI: 10.1002/slct.201800992

Complexes of aminobenzoic acids: A comprehensive review concerning synthesis, physical chemistry, structure and application

Jan Kalembkiewicz, Małgorzata Kosińska and Lidia Zapała

Coordination Chemistry Reviews, 2017, 348, 25
DOI: 10.1016/j.ccr.2017.07.004

Synthesis, structural, thermal elucidation and in vitro anticancer activity of novel silver(I) complexes with non-steroidal anti-inflammatory drugs diclofenac and mefenamic acid including picoline derivatives

Ahmet Altay, Sema Caglar, Bulent Caglar and Onur Sahin

Polyhedron, 2018, 151, 160
DOI: 10.1016/j.poly.2018.05.038

Design, Synthesis, In vitro and In silico Alpha Glucosidase and Lipoxygenase Inhibition Studies of Copper(II) Oxamide Complexes

Naseema Perveen Malik, Uzma Ashiq, Rifat Ara Jamal, Sana Gul and Mehreen Lateef

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202400398

Synthesis, crystal structure, spectroscopy, thermal properties and carbonic anhydrase activities of new metal(II) complexes with mefenamic acid and picoline derivatives

Esra Dilek, Sema Caglar, Nesrin Dogancay, Bulent Caglar, Onur Sahin and Ahmet Tabak

Journal of Coordination Chemistry, 2017, 70, 2833
DOI: 10.1080/00958972.2017.1366996

Biological evaluation of copper(II) complex with nalidixic acid and 2,2′-bipyridine (bpy)

Manish Kumar, Navin Kumar Mogha, Gyanendra Kumar, Firasat Hussain and Dhanraj T. Masram

Inorganica Chimica Acta, 2019, 490, 144
DOI: 10.1016/j.ica.2019.03.011

A dual pH/Redox responsive copper-ligand nanoliposome bioactive complex for the treatment of chronic inflammation

Simphiwe Mavuso, Yahya E. Choonara, Thashree Marimuthu, Pradeep Kumar, Lisa C. du Toit, Pierre P.D. Kondiah and Viness Pillay

International Journal of Pharmaceutics, 2016, 509, 348
DOI: 10.1016/j.ijpharm.2016.05.069

Invitro cytotoxicity and DNA interaction studies of nickel(II) mefenamato compounds with substituted α-diimines

Beena K. Vernekar, Nikita N. Harmalkar, Sanket K. Gaonkar, Delicia A. Barretto, Deepika Maliwal, Raghuvir R. Pissurlenkar, Pradip K. Bhowmik and Sunder N. Dhuri

Journal of Molecular Structure, 2025, 1345, 141694
DOI: 10.1016/j.molstruc.2025.141694

Co(II) fenamato, tolfenamato and niflumato complexes with neocuproine: Synthesis, crystal structure, spectral characterization and biological activity

Romana Smolková, Lukáš Smolko, Erika Samoľová and Michal Dušek

Journal of Molecular Structure, 2023, 1272, 134172
DOI: 10.1016/j.molstruc.2022.134172

New fluorescent probe for sensing of mefenamic acid in aqueous medium: An integrated experimental and theoretical analysis

Sanwa Rafique, Abdullah Yahya Abdullah Alzahrani, Khadija, Hasher Irshad, Asad Muhammad Khan and Sohail Anjum Shahzad

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 300, 122946
DOI: 10.1016/j.saa.2023.122946

Crystal structures, in vitro and in silico biological studies of copper mefenamato complexes with aliphatic diamines

Beena K. Vernekar, Pradnya S. Sawant, Jaxon Breckell, Gayatri Kotkar, Luann R. D’souza, Raymond J. Butcher and Christopher Richardson

Journal of Molecular Structure, 2026, 1349, 143585
DOI: 10.1016/j.molstruc.2025.143585

Double Palindrome Water Chain in Cu(II) Theophylline Complex. Synthesis, Characterization, Biological Activity of Cu(II), Zn(II) Complexes with Theophylline

Michał Gacki, Karolina Kafarska, Anna Pietrzak, Izabela Korona-Głowniak and Wojciech M. Wolf

Crystals, 2020, 10, 97
DOI: 10.3390/cryst10020097

Manganese coordination compounds of mefenamic acid: In vitro screening and in silico prediction of biological activity

Alketa Tarushi, George D. Geromichalos, Dimitris P. Kessissoglou and George Psomas

Journal of Inorganic Biochemistry, 2019, 190, 1
DOI: 10.1016/j.jinorgbio.2018.09.017

Manganese (II)-imidazole complexes of the non-steroidal anti-inflammatory drug mefenamic acid: Synthesis, and structural studies

Aarti Borkar, Ginikachukwu G. Nnabuike, Joshua Ayoola Obaleye, Shital Harihar, Archana S. Patil, Ray J. Butcher and Sunita Salunke-Gawali

Inorganica Chimica Acta, 2020, 512, 119878
DOI: 10.1016/j.ica.2020.119878

Synthesis, spectral and thermal study of La(III), Nd(III), Sm(III), Eu(III), Gd(III) and Tb(III) complexes with mefenamic acid

Lidia Zapała, Małgorzata Kosińska, Elżbieta Woźnicka, Łukasz Byczyński and Wojciech Zapała

J Therm Anal Calorim, 2016, 124, 363
DOI: 10.1007/s10973-015-5120-0

Targeting of the intracellular redox balance by metal complexes towards anticancer therapy

María Isabel Murillo, Christian Gaiddon and Ronan Le Lagadec

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.967337

In vitro and in silico study of the biological activity of manganese(III) inverse-[9-MC-3]-metallacrowns and manganese(II) complexes with the anti-inflammatory drugs diclofenac or indomethacin

George D. Geromichalos, Alketa Tarushi, Konstantinos Lafazanis, Anastasia A. Pantazaki, Dimitris P. Kessissoglou and George Psomas

Journal of Inorganic Biochemistry, 2018, 187, 41
DOI: 10.1016/j.jinorgbio.2018.07.007

Trinuclear and tetranuclear iron(III) complexes with fenamates: Structure and biological profile

Filitsa Dimiza, Antonios G. Hatzidimitriou, Yiannis Sanakis, Athanasios N. Papadopoulos and George Psomas

Journal of Inorganic Biochemistry, 2021, 218, 111410
DOI: 10.1016/j.jinorgbio.2021.111410

Non‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) in Metal Complexes and Their Effect at the Cellular Level

Christina N. Banti and Sotiris K. Hadjikakou

Eur J Inorg Chem, 2016, 2016, 3048
DOI: 10.1002/ejic.201501480

Synthesis, Spectroscopic, and Thermal Investigations of Metal Complexes with Mefenamic Acid

Karolina Kafarska, Michał Gacki and Wojciech M. Wolf

Journal of Chemistry, 2017, 2017, 1
DOI: 10.1155/2017/6172626

Cytotoxic Effects of Diclofenac and Ibuprofen Zinc (II)-Nicotinamide Ternary Complexes in Breast Cancer Cell Lines

Emanuelle Fraga da Silva, Paulo Roberto dos Santos, Krist Helen Antunes Fernandes, Deise do Nascimento de Freitas, Rafael Fernandes Zanin, Pablo Machado, Sidnei Moura and Ana Paula Duarte de Souza

Braz. arch. biol. technol., 2021, 64
DOI: 10.1590/1678-4324-2021210019

Calcium Complexes of Oxicams: New Dimensions in Rheumatoid Arthritis Treatment

Aatika Sadia, Tahira Yasmin, Muhammad Imran, Malka M Samra and Muhammad Asim Raza Basra

Future Med. Chem., 2022, 14, 1771
DOI: 10.4155/fmc-2022-0032

Manganese(II) complexes of tolfenamic acid or naproxen in polymeric structures or encapsulated in [15-MC-5] manganese(III) metallacrowns: Structure and biological activity

Alketa Tarushi, Marianthi Zampakou, Spyros Perontsis, Konstantinos Lafazanis, Anastasia A. Pantazaki, Antonios G. Hatzidimitriou, George D. Geromichalos and George Psomas

Inorganica Chimica Acta, 2018, 483, 579
DOI: 10.1016/j.ica.2018.09.001

Novel silver(I) complexes bearing mefenamic acid and pyridine derivatives: Synthesis, chemical characterization and in vitro anticancer evaluation

Ahmet Altay, Sema Caglar, Bulent Caglar and Zarife Sibel Sahin

Inorganica Chimica Acta, 2019, 493, 61
DOI: 10.1016/j.ica.2019.05.008

Synthesis, characterization, and in vitro effect of the Cu(II) complex with niflumic acid and 3‐picoline on paraoxanase‐I

Esra Dilek, Sema Caglar, Seda Çardak, Barış Karakoç, Bülent Caglar and Onur Sahin

Archiv der Pharmazie, 2019, 352
DOI: 10.1002/ardp.201900007

Quasi-Isostructural Co(II) and Ni(II) Complexes with Mefenamato Ligand: Synthesis, Characterization, and Biological Activity

Michał Gacki, Karolina Kafarska, Anna Pietrzak, Izabela Korona-Głowniak and Wojciech M. Wolf

Molecules, 2020, 25, 3099
DOI: 10.3390/molecules25133099

New Apoptosis Inducers Containing Anti-inflammatory Drugs and Pnictogen Derivatives: A New Strategy in the Development of Mitochondrial Targeting Chemotherapeutics

Christina N. Banti, Constantina Papatriantafyllopoulou, Christina Papachristodoulou, Antonios G. Hatzidimitriou and Sotiris K. Hadjikakou

J. Med. Chem., 2023, 66, 4131
DOI: 10.1021/acs.jmedchem.2c02126

Toward Multifunctional Materials Incorporating Stepladder Manganese(III) Inverse-[9-MC-3]-Metallacrowns and Anti-Inflammatory Drugs

Alketa Tarushi, Antonios G. Hatzidimitriou, Marta Estrader, Dimitris P. Kessissoglou, Vassilis Tangoulis and George Psomas

Inorg. Chem., 2017, 56, 7048
DOI: 10.1021/acs.inorgchem.7b00655