Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

Davin Tan, Leigh Loots and Tomislav Friščić

Chem. Commun., 2016, 52, 7760
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Diversity of felodipine solvates: structure and physicochemical properties

Artem O. Surov, Katarzyna A. Solanko, Andrew D. Bond, Annette Bauer-Brandl and German L. Perlovich

CrystEngComm, 2015, 17, 4089
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Crystallisation, thermal analysis and acetal protection activity of new layered Zn(ii) hybrid polymorphs

Salem Saïd, Houcine Naïli, Thierry Bataille and Raquel P. Herrera

CrystEngComm, 2016, 18, 5365
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Designing a new cocrystal of olanzapine drug and observation of concomitant polymorphism in a ternary cocrystal system

Jagadeesh Babu Nanubolu and Krishnan Ravikumar

CrystEngComm, 2017, 19, 355
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Prediction of solubility of two-component molecular crystals

German L. Perlovich

CrystEngComm, 2022, 24, 2217
DOI: 10.1039/D2CE00105E

Exploring molecular reorientations in amorphous and recrystallized felodipine at the microscopic level

A. Pajzderska, J. Jenczyk, J. P. Embs and J. Wąsicki

RSC Adv., 2020, 10, 37346
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Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals

Anne Marie Healy, Zelalem Ayenew Worku, Dinesh Kumar and Atif M. Madi

Advanced Drug Delivery Reviews, 2017, 117, 25
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Can vacuum morphologies predict solubility and intrinsic dissolution rate? A case study with felodipine polymorph form IV

Dinesh Kumar, Rajesh Thipparaboina and Nalini R. Shastri

Journal of Computational Science, 2015, 10, 178
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Synthesis, characterization, solubility and photostability enhancement of felodipine co-crystals featuring a novel single-crystal structure

Zhong-hua Sun, Zhao Yang, Yan Zhang, Hong Xu, Ru-mei Liu, Da-zhong Ding, Yang Li, Yun-jie Zhu, Min Li and Ping Leng

Journal of Molecular Structure, 2025, 1345, 141678
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Pharmaceutical Cocrystals of Diflunisal and Diclofenac with Theophylline

Artem O. Surov, Alexander P. Voronin, Alex N. Manin, Nikolay G. Manin, Lyudmila G. Kuzmina, Andrei V. Churakov and German L. Perlovich

Mol. Pharmaceutics, 2014, 11, 3707
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Novel perchlorate and phosphate salts of vinpocetine: Characterization, relative solid-state stability evaluation and Hirshfeld surface analysis

Yu-heng Ma, Shu-wang Ge, Wei Wang, Qiang Zheng, Yun-wei Zuo, Chang-jiang Zhong and Bai-wang Sun

Journal of Molecular Structure, 2016, 1105, 1
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Melting points of one- and two-component molecular crystals as effective characteristics for rational design of pharmaceutical systems

German Perlovich

Acta Crystallogr B Struct Sci Cryst Eng Mater, 2020, 76, 696
DOI: 10.1107/S2052520620007362

Rational Design of the Carbamazepine Ternary Cocrystals

Denis E. Boycov, Ksenia V. Drozd, Alex N. Manin, Andrey V. Churakov and German L. Perlovich

Crystal Growth & Design, 2024, 24, 4862
DOI: 10.1021/acs.cgd.4c00529

Celecoxib–Nicotinamide Cocrystal Revisited: Can Entropy Control Cocrystal Formation?

Si-Wei Zhang, Andrew P. J. Brunskill, Eric Schwartz and Shuwen Sun

Crystal Growth & Design, 2017, 17, 2836
DOI: 10.1021/acs.cgd.7b00308

Hesperetin–4,4′-bipyridine cocrystal: Polymorphism, crystal structures, and thermodynamic relationship

Yujing Zhu, Lin Wang, Jiangying Li, Xiaoju Shi, Zongwu Deng and Hailu Zhang

Journal of Molecular Structure, 2025, 1320, 139719
DOI: 10.1016/j.molstruc.2024.139719

Monoclinic Paracetamol vs. Paracetamol-4,4′-Bipyridine Co-Crystal; What Is the Difference? A Charge Density Study

Jonathan Du, Felcia Lai, Linda Váradi, Peter Williams, Paul Groundwater, James Platts, David Hibbs and Jacob Overgaard

Crystals, 2018, 8, 46
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Polymorphism and stability of ibuprofen/nicotinamide cocrystal: The effect of the crystalline synthesis method

M. Guerain, Y. Guinet, N.T. Correia, L. Paccou, F. Danède and A. Hédoux

International Journal of Pharmaceutics, 2020, 584, 119454
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Vibrational Response of Felodipine in the THz Domain: Optical and Neutron Spectroscopy Versus Plane-Wave DFT Modeling

Katarzyna Łuczyńska, Kacper Drużbicki, Tomasz Runka, Norbert Pałka and Jan Węsicki

J Infrared Milli Terahz Waves, 2020, 41, 1301
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Fenamate Cocrystals with 4,4′-Bipyridine: Structural and Thermodynamic Aspects

Artem O. Surov, Anna A. Simagina, Nikolay G. Manin, Lyudmila G. Kuzmina, Andrei V. Churakov and German L. Perlovich

Crystal Growth & Design, 2015, 15, 228
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Zaltoprofen/4,4′-Bipyridine: A Case Study to Demonstrate the Potential of Differential Scanning Calorimetry (DSC) in the Pharmaceutical Field

Giovanna Bruni, Lauretta Maggi, Francesco Monteforte, Chiara Ferrara, Doretta Capsoni, Vittorio Berbenni, Chiara Milanese, Alessandro Girella, Valeria Friuli, Piercarlo Mustarelli and Amedeo Marini

Journal of Pharmaceutical Sciences, 2021, 110, 3690
DOI: 10.1016/j.xphs.2021.08.009

Using Electron Density to Predict Synthon Formation in a 4-Hydroxybenzoic Acid: 4,4′-Bipyridine Cocrystal

Jonathan J. Du, Stephen A. Stanton, Peter A. Williams, Jennifer A. Ong, Paul W. Groundwater, Jacob Overgaard, James A. Platts and David E. Hibbs

Crystal Growth & Design, 2018, 18, 1786
DOI: 10.1021/acs.cgd.7b01676

Cocrystal screening of anticancer drug p-toluenesulfonamide and preparation by supercritical antisolvent process

Salal Hasan Khudaida, Yu-Tse Yen and Chie-Shaan Su

The Journal of Supercritical Fluids, 2024, 204, 106106
DOI: 10.1016/j.supflu.2023.106106

Solid-State Characterization and Relative Formation Enthalpies To Evaluate Stability of Cocrystals of an Antidiabetic Drug

Naga Kiran Duggirala, Heather L. Frericks Schmidt, Zhaohui Lei, Michael J. Zaworotko, Joseph F. Krzyzaniak and Kapildev K. Arora

Mol. Pharmaceutics, 2018, 15, 1901
DOI: 10.1021/acs.molpharmaceut.8b00061

Cocrystal Polymorphs and Solvates of the Anti-Trypanosoma cruzi Drug Benznidazole with Improved Dissolution Performance

Beatriz Pinheiro Bezerra, Dorota Pogoda, Miranda L. Perry, Laura M. T. Vidal, Michael J. Zaworotko and Alejandro P. Ayala

Crystal Growth & Design, 2020, 20, 4707
DOI: 10.1021/acs.cgd.0c00490

Multicomponent solid forms of felodipine: preparation, characterisation, physicochemical and in-vivo studies

Renu Chadha, Mohit Sharma and Jamshed Haneef

Journal of Pharmacy and Pharmacology, 2017, 69, 254
DOI: 10.1111/jphp.12685

Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov and German L. Perlovich

Crystal Growth & Design, 2022, 22, 2569
DOI: 10.1021/acs.cgd.2c00044

DRUG DEVELOPMENT BASED ON PHARMACEUTICAL ALTERNATIVES

A. A Spasov and V. A Kosolapov

Journal of Volgograd State Medical University, 2018, 15, 3
DOI: 10.19163/1994-9480-2018-3(67)-3-7