Issue 12, 2024

Biological fate, functional properties, and design strategies for oral delivery systems for cinnamaldehyde

Abstract

Cinnamaldehyde (CA) is the main bioactive component extracted from the internal bark of cinnamon trees with many health benefits. In this paper, the bioavailability and biological activities of cinnamaldehyde, and the underlying molecular mechanism are reviewed and discussed, including antioxidant, cardioprotective, anti-inflammatory, anti-obesity, anticancer, and antibacterial properties. Common delivery systems that could improve the stability and bioavailability of CA are also summarized and evaluated, such as micelles, microcapsules, liposomes, nanoparticles, and nanoemulsions. This work provides a comprehensive understanding of the beneficial functions and delivery strategies of CA, which is useful for the future application of CA in the functional food industry.

Graphical abstract: Biological fate, functional properties, and design strategies for oral delivery systems for cinnamaldehyde

Article information

Article type
Review Article
Submitted
05 feb 2024
Accepted
08 mai 2024
First published
09 mai 2024

Food Funct., 2024,15, 6217-6231

Biological fate, functional properties, and design strategies for oral delivery systems for cinnamaldehyde

X. Weng, C. Ho and M. Lu, Food Funct., 2024, 15, 6217 DOI: 10.1039/D4FO00614C

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