Issue 8, 2022

Controllable high-performance liquid marble micromixer

Abstract

A liquid marble is a liquid droplet coated with a shell of microparticles. Liquid marbles have served as a unique microreactor for chemical reactions and cell culture. Mixing is an essential task for liquid marbles as a microreactor. However, the potential of liquid marble-based microreactors is significantly limited due to the lack of effective mixing strategies. Most mixing strategies used manual and contact-based actuation schemes. This paper reports the development of a manipulation scheme that induces fluid motion into a liquid marble, leading to enhanced mixing. By inducing rotation on a horizontal axis, we significantly increased the mixing rate by 27.6 times compared to a non-actuated liquid marble and reduced the reaction time by more than 10 times. The proposed method provides a simple, continuous, precise, and controllable high-performance mixing strategy on a liquid marble platform.

Graphical abstract: Controllable high-performance liquid marble micromixer

Supplementary files

Article information

Article type
Paper
Submitted
07 jan 2022
Accepted
17 mar 2022
First published
20 mar 2022

Lab Chip, 2022,22, 1508-1518

Controllable high-performance liquid marble micromixer

N. Nguyen, P. Singha, Y. Dai, K. Rajan Sreejith, D. T. Tran, H. Phan, N. Nguyen and C. H. Ooi, Lab Chip, 2022, 22, 1508 DOI: 10.1039/D2LC00017B

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