Issue 92, 2022

Stimuli-responsive fluorescent nanogel: a nonconventional donor for ratiometric temperature and pH sensing

Abstract

A reactive stimuli responsive fluorescent polyaminoamide nanogel (NANO-PAMAM) is synthesized via an aza-Michael polyaddition reaction in water. In the next stage, doxorubicin (a FRET acceptor) is covalently linked with the nanogel (NANO-PAMAM, a nonconventional FRET donor) to form a ratiometric nanosensor for temperature and pH sensing. MTT assay revealed comparable biocompatibility of the donor nanogels (NANO-PAMAM) and nanosensors (NANO-PAMAM-DOX).

Graphical abstract: Stimuli-responsive fluorescent nanogel: a nonconventional donor for ratiometric temperature and pH sensing

Supplementary files

Article information

Article type
Communication
Submitted
01 sep 2022
Accepted
05 okt 2022
First published
07 okt 2022

Chem. Commun., 2022,58, 12807-12810

Stimuli-responsive fluorescent nanogel: a nonconventional donor for ratiometric temperature and pH sensing

S. Ghosh, M. Avais and S. Chattopadhyay, Chem. Commun., 2022, 58, 12807 DOI: 10.1039/D2CC04852C

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