Issue 1, 2024

Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

Abstract

Bacillus anthracis is an extremely dangerous bacterium that causes high morbidity and mortality. Developing a simple and effective sensor to detect its unique biomarker 2,6-pyridine dicarboxylic acid (DPA) is urgently required to prevent anthrax infection. In this work, a ratiometric fluorescence sensor based on lanthanide–metal–organic frameworks (MOFs) was developed for the sensitive and selective recognition of DPA. Eu-MOF was successfully synthesised by Eu3+, 2,5-thiophenedicarboxylic acid, 2-aminoterephthalic acid, and dimethylformamide (DMF) through a simple solvothermal method. The rationally designed Eu-MOF not only exhibited outstanding sensitivity, strong stability and excellent anti-interference ability for DPA detection but also realised an obvious naked-eye colour change from red to blue with the increasing DPA concentration under UV light. Moreover, a possible detection mechanism involving hydrogen bonding, coordination and photoinduced electron transfer between the Eu-MOF and DPA was proposed. More importantly, the application of Eu-MOF probes in fetal calf serum and tap water also obtained satisfactory results, and the Eu-MOF probes were immobolised onto polyvinyl alcohol membrane, achieving a portable and convenient approach to monitoring DPA.

Graphical abstract: Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

Supplementary files

Article information

Article type
Research Article
Submitted
14 sep 2023
Accepted
08 nov 2023
First published
17 nov 2023

Inorg. Chem. Front., 2024,11, 269-277

Eu3+-MOF fluorescence sensor based on a dual-ligand strategy for visualised detection of an anthrax biomarker 2,6-pyridine dicarboxylic acid

R. Wang, H. Zhang, J. Sun and Z. Su, Inorg. Chem. Front., 2024, 11, 269 DOI: 10.1039/D3QI01852K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements