Issue 8, 2024

Nanotechnology-enabled sonodynamic therapy against malignant tumors

Abstract

Sonodynamic therapy (SDT) is an emerging approach for malignant tumor treatment, offering high precision, deep tissue penetration, and minimal side effects. The rapid advancements in nanotechnology, particularly in cancer treatment, have enhanced the efficacy and targeting specificity of SDT. Combining sonodynamic therapy with nanotechnology offers a promising direction for future cancer treatments. In this review, we first systematically discussed the anti-tumor mechanism of SDT and then summarized the common nanotechnology-related sonosensitizers and their recent applications. Subsequently, nanotechnology-related therapies derived using the SDT mechanism were elaborated. Finally, the role of nanomaterials in SDT combined therapy was also introduced.

Graphical abstract: Nanotechnology-enabled sonodynamic therapy against malignant tumors

Article information

Article type
Review Article
Submitted
05 sep 2023
Accepted
09 feb 2024
First published
26 mar 2024
This article is Open Access
Creative Commons BY-NC license

Nanoscale Adv., 2024,6, 1974-1991

Nanotechnology-enabled sonodynamic therapy against malignant tumors

Y. Huang, W. Ouyang, Z. Lai, G. Qiu, Z. Bu, X. Zhu, Q. wang, Y. Yu and J. Liu, Nanoscale Adv., 2024, 6, 1974 DOI: 10.1039/D3NA00738C

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