Issue 13, 2024

Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy

Abstract

Live chicken egg embryos offer new opportunities for evaluation and continuous monitoring of tumour growth for in vivo studies compared to traditional rodent models. Here, we report the first use of surface enhanced Raman scattering (SERS) mapping and surface enhanced spatially offset Raman scattering (SESORS) for the detection and localisation of targeted gold nanoparticles in live chicken egg embryos bearing a glioblastoma tumour.

Graphical abstract: Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy

Supplementary files

Article information

Article type
Communication
Submitted
26 apr 2024
Accepted
02 jun 2024
First published
04 jun 2024
This article is Open Access
Creative Commons BY license

Analyst, 2024,149, 3513-3517

Live chicken egg embryos as an alternative in vivo tumour model for deep surface enhanced Raman spectroscopy

S. M. McCabe, H. Gardiner, C. Mullen, G. Q. Wallace, N. C. Shand, A. B. Mullen, L. Horan, D. Graham, K. Faulds and M. Boyd, Analyst, 2024, 149, 3513 DOI: 10.1039/D4AN00617H

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