Issue 39, 2023

Recent theranostic applications of hydrogen peroxide-responsive nanomaterials for multiple diseases

Abstract

It is well established that hydrogen peroxide (H2O2) is associated with the initiation and progression of many diseases. With the rapid development of nanotechnology, the diagnosis and treatment of those diseases could be realized through a variety of H2O2-responsive nanomaterials. In order to broaden the application prospects of H2O2-responsive nanomaterials and promote their development, understanding and summarizing the design and application fields of such materials has attracted much attention. This review provides a comprehensive summary of the types of H2O2-responsive nanomaterials including organic, inorganic and organic-inorganic hybrids in recent years, and focused on their specific design and applications. Based on the type of disease, such as tumors, bacteria, dental diseases, inflammation, cardiovascular diseases, bone injury and so on, key examples for above disease imaging diagnosis and therapy strategies are introduced. In addition, current challenges and the outlook of H2O2-responsive nanomaterials are also discussed. This review aims to stimulate the potential of H2O2-responsive nanomaterials and provide new application ideas for various functional nanomaterials related to H2O2.

Graphical abstract: Recent theranostic applications of hydrogen peroxide-responsive nanomaterials for multiple diseases

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Article information

Article type
Review Article
Submitted
25 jul 2023
Accepted
31 aug 2023
First published
12 sep 2023
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2023,13, 27333-27358

Recent theranostic applications of hydrogen peroxide-responsive nanomaterials for multiple diseases

L. Huang, Y. Su, D. Zhang, Z. Zeng, X. Hu, S. Hong and X. Lin, RSC Adv., 2023, 13, 27333 DOI: 10.1039/D3RA05020C

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