Issue 8, 2022

A novel phage display based platform for exosome diversity characterization

Abstract

We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.

Graphical abstract: A novel phage display based platform for exosome diversity characterization

Supplementary files

Article information

Article type
Communication
Submitted
14 okt 2021
Accepted
04 jan 2022
First published
18 jan 2022

Nanoscale, 2022,14, 2998-3003

A novel phage display based platform for exosome diversity characterization

D. Maisano, S. Mimmi, V. Dattilo, F. Marino, M. Gentile, E. Vecchio, G. Fiume, N. Nisticò, A. Aloisio, M. P. de Santo, G. Desiderio, V. Musolino, S. Nucera, F. Sbrana, S. Andò, S. Ferrero, A. Morandi, F. Bertoni, I. Quinto and E. Iaccino, Nanoscale, 2022, 14, 2998 DOI: 10.1039/D1NR06804K

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