Issue 28, 2022

Liposome triggered content release through molecular recognition of inositol trisphosphate

Abstract

A stimuli-responsive liposomal platform that is selectively activated by inositol 1,4,5-trisphosphate (IP3) over eleven other phosphorylated metabolites is reported. Dye release assays validated dose-dependent release of both hydrophilic and hydrophobic cargo driven by IP3, showcasing the potential of this platform for triggered release and sensing applications.

Graphical abstract: Liposome triggered content release through molecular recognition of inositol trisphosphate

Supplementary files

Article information

Article type
Communication
Submitted
15 feb 2022
Accepted
14 mar 2022
First published
14 mar 2022

Chem. Commun., 2022,58, 4520-4523

Author version available

Liposome triggered content release through molecular recognition of inositol trisphosphate

S. E. Bottcher, J. Lou and M. D. Best, Chem. Commun., 2022, 58, 4520 DOI: 10.1039/D2CC00951J

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