Issue 47, 2021

A review on convenient synthesis of substituted coumarins using reuseable solid acid catalysts

Abstract

Due to growing concern about chemicals and their impact on the environment, cleaner reaction conditions are needed to be incorporated into chemical synthetic procedures. Recently, the use of heteropolyacid catalysts, mainly reuseable solid acid catalysts, has gained a leading role in organic synthesis due to their environmental and economic considerations and industrial utilization. The high catalytic activity, moisture sensitivity, reusability and inexpensive makes solid supported reagents attractive substituents to conventional Lewis acids. Nowadays synthesis of coumarins and their derivatives has attracted considerable attention from organic and medicinal chemists for many years as a large number of natural products contain this heterocyclic nucleus. In continuation with our investigations into the synthesis of substituted coumarins and due to several advantages of heterogeneous catalysts viz. cost-effective, no side products, high yield of desired products and no toxic waste material, here we report a new approach for the synthesis of substituted coumarins using solid acid catalysts.

Graphical abstract: A review on convenient synthesis of substituted coumarins using reuseable solid acid catalysts

Article information

Article type
Review Article
Submitted
23 jun 2021
Accepted
19 aug 2021
First published
01 sep 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 29130-29155

A review on convenient synthesis of substituted coumarins using reuseable solid acid catalysts

S. Gulati, R. Singh and S. Sangwan, RSC Adv., 2021, 11, 29130 DOI: 10.1039/D1RA04887B

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