Issue 49, 2018

Beyond a solvent: triple roles of dimethylformamide in organic chemistry

Abstract

N,N-Dimethylformamide (DMF) is frequently used as an aprotic solvent in chemical transformations in laboratories of academia as well as in those of chemical industry. In the present review, we will reveal that DMF is actually something much more than a solvent. It is a unique chemical since, as well as being an effective polar aprotic solvent, it can play three other important roles in organic chemistry. It can be used as a reagent, a catalyst, and a stabilizer.

Graphical abstract: Beyond a solvent: triple roles of dimethylformamide in organic chemistry

Article information

Article type
Review Article
Submitted
11 jun 2018
Accepted
23 jul 2018
First published
03 aug 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 27832-27862

Beyond a solvent: triple roles of dimethylformamide in organic chemistry

Majid M. Heravi, M. Ghavidel and L. Mohammadkhani, RSC Adv., 2018, 8, 27832 DOI: 10.1039/C8RA04985H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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