Issue 50, 2018

A chiral aluminum solvating agent (CASA) for 1H NMR chiral analysis of alcohols at low temperature

Abstract

A chiral aluminum solvating agent (CASA) was demonstrated to be a general and efficient reagent for 1H NMR chiral analysis of alcohols. The sodium salt of the CASA (CASA-Na) showed a complete baseline peak separation of the hydroxyl group for various chiral alcohols including primary, secondary, and tertiary alcohols with alkyl and aryl substituents in CD3CN. Due to the weak intermolecular interaction, 1H NMR measurement at low temperature (−40 to 10 °C) was required.

Graphical abstract: A chiral aluminum solvating agent (CASA) for 1H NMR chiral analysis of alcohols at low temperature

Supplementary files

Article information

Article type
Communication
Submitted
23 jan 2018
Accepted
05 mar 2018
First published
06 mar 2018

Chem. Commun., 2018,54, 6804-6807

A chiral aluminum solvating agent (CASA) for 1H NMR chiral analysis of alcohols at low temperature

M. Seo, S. Jang and H. Kim, Chem. Commun., 2018, 54, 6804 DOI: 10.1039/C8CC00574E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements