Issue 19, 2016

Pyrene-based heparin sensors in competitive aqueous media – the role of self-assembled multivalency (SAMul)

Abstract

Amine-functionalised pyrene derivatives are reported and their ability to detect heparin via a fluorescent response determined – different responses are observed dependent on whether self-assembled multivalent binding between sensor and analyte takes place, and ratiometric heparin sensors which can detect this surgically-relevant polyanion in competitive media are reported.

Graphical abstract: Pyrene-based heparin sensors in competitive aqueous media – the role of self-assembled multivalency (SAMul)

Supplementary files

Article information

Article type
Communication
Submitted
08 jan 2016
Accepted
01 feb 2016
First published
08 feb 2016

Chem. Commun., 2016,52, 3785-3788

Author version available

Pyrene-based heparin sensors in competitive aqueous media – the role of self-assembled multivalency (SAMul)

C. W. Chan and D. K. Smith, Chem. Commun., 2016, 52, 3785 DOI: 10.1039/C6CC00163G

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