Issue 12, 2014

Recent development of direct asymmetric functionalization of inert C–H bonds

Abstract

The area of direct asymmetric functionalization of inert C–H bonds has attracted considerable attention in recent years. To realize this type of challenging but promising transformations, a lot of strategies have emerged including asymmetric C–H bond insertion by metal carbenoids or analogs, cross dehydrogenative coupling, [1,5]-hydride transfer, C–H bond functionalization involving a transient metal–carbon species and other miscellaneous methods. This review is intended to summarize and discuss the most recent developments (contributions mainly after 2009) within this area.

Graphical abstract: Recent development of direct asymmetric functionalization of inert C–H bonds

Article information

Article type
Review Article
Submitted
19 sep 2013
Accepted
05 des 2013
First published
06 des 2013

RSC Adv., 2014,4, 6173-6214

Recent development of direct asymmetric functionalization of inert C–H bonds

C. Zheng and S. You, RSC Adv., 2014, 4, 6173 DOI: 10.1039/C3RA46996D

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