Issue 40, 2017

A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

Abstract

A biotin–rhodamine–TPP conjugate (BiTClO) was reported as a real-time (within 10 s) fluorescent probe for the sensing of mitochondrial hypochlorite with excellent selectivity and high sensitivity (0.21 μM). Moreover, it is the first tumor-specific and mitochondria-targeted fluorescent probe applied in cell imaging.

Graphical abstract: A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

Supplementary files

Article information

Article type
Communication
Submitted
04 mar 2017
Accepted
18 apr 2017
First published
18 apr 2017

Chem. Commun., 2017,53, 5539-5541

A tumor-specific and mitochondria-targeted fluorescent probe for real-time sensing of hypochlorite in living cells

K. Li, J. Hou, J. Yang and X. Yu, Chem. Commun., 2017, 53, 5539 DOI: 10.1039/C7CC01679D

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